Results 191 to 200 of about 13,872 (224)

Biosynthesis of Isoprenoids

1984
Isoprenoids (= terpenoids or terpenes) are constructed from isoprene (2-methyl-butadiene) units: Open image in new ...
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Biosynthesis and engineering of isoprenoid small molecules

Applied Microbiology and Biotechnology, 2007
Isoprenoid secondary metabolites are a rich source of commercial products that have not been fully explored. At present, there are isoprenoid products used in cancer therapy, the treatment of infectious diseases, and crop protection. All isoprenoids share universal prenyl diphosphate precursors synthesized via two distinct pathways.
Sydnor T, Withers, Jay D, Keasling
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Genetics of isoprenoid biosynthesis in Paracoccus zeaxanthinifaciens

Gene, 2002
The genes coding for all the enzymes involved in the conversion of acetyl-CoA to farnesyl diphosphate (FPP) in the zeaxanthin-producing bacterium Paracoccus zeaxanthinifaciens were cloned and characterized. Two genes encoding enzymes catalysing the condensation of two acetyl-CoA molecules to acetoacetyl-CoA were found.
Hümbelin, M., Thomas, A., Lin, J., Li, J., Jore, J., Berry, A.   +5 more
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Biosynthesis of isoprenoid compounds in Schistosoma mansoni

Molecular and Biochemical Parasitology, 1993
The isoprenoid biosynthetic capacity of digenetic trematodes was investigated by following the fate of [14C]mevalonic acid incorporated by Schistosoma mansoni during maintenance in axenic culture. Isoprenoid compounds were analyzed by thin-layer chromatography and high-performance liquid chromatography.
J M, Foster, J F, Pennock, I, Marshall, H H, Rees   +3 more
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Isoprenoid Biosynthesis of the Apicoplast as Drug Target

Current Drug Targets, 2007
In Plasmodium falciparum the biosynthesis of isoprenoids is achieved by the mevalonate-independent 1-deoxy-d-xylulose 5-phosphate (DOXP) pathway. The enzymes of the DOXP pathway are localised inside the plastid-like organelle (apicoplast). Fosmidomycin inhibits DOXP reductoisomerase, the second enzyme of this pathway.
Jochen, Wiesner, Hassan, Jomaa
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Biosynthesis of Isoprenoid Compounds

Annual Review of Biochemistry, 1961
Sir Alexander Todd has recently stated (1): "The unravelling of the actual biosyn thetic pathway to the terpen ids and the sterols is one of the outstand­ ing achievements of recent years." It is now possible to write every reaction and name every intermediate in the biosynthesis of cholesterol from acetate with a reasonable degree of certainty.
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Isoprenoid-like alkylations in polyketide biosynthesis

Natural Product Reports, 2008
Polyketides are secondary metabolites biosynthesized by the iterative Claisen condensation of malonate units. Despite utilizing only a small set of biochemical transformations, the polyketide biosynthetic machinery yields products of striking structural complexity and diversity.
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Organization of isoprenoid biosynthesis

Biochemical Society Transactions, 1996
I, Parmryd, G, Dallner
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Isoprenoid Biosynthesis in Prokaryotic Organisms

2012
Isoprenoids are ubiquitous compounds found in all living organisms. In spite of their remarkable diversity of structures and functions, all isoprenoids derive from a basic five-carbon precursor unit, isopentenyl diphosphate (IPP), and its isomer dimethylallyl diphosphate (DMAPP).
Manuel Rodríguez-Concepción, Albert Boronat   +1 more
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The Role Of Plastids In Isoprenoid Biosynthesis

Annual Review of Plant Physiology and Plant Molecular Biology, 1989
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