Results 1 to 10 of about 5,596 (182)

Isoprenoid biosynthesis regulation in poplars by methylerythritol phosphate and mevalonic acid pathways [PDF]

open access: yesFrontiers in Plant Science, 2022
It is critical to develop plant isoprenoid production when dealing with human-demanded industries such as flavoring, aroma, pigment, pharmaceuticals, and biomass used for biofuels.
Ali Movahedi   +11 more
doaj   +2 more sources

Mevalonic acid exerts procoagulant effect by potentiating factor Xa [PDF]

open access: yesNatural Products and Bioprospecting
Thrombosis pathogenesis is closely linked to dysregulated lipid metabolism and inflammatory processes. However, the direct regulatory role of mevalonate pathway within the coagulation cascade is still not well understood.
Liyuan Niu   +12 more
doaj   +2 more sources

An ultrasensitive enzymatic method for measuring mevalonic acid in serum [PDF]

open access: yesJournal of Lipid Research, 2012
We have developed a simple, precise, and ultrasensitive enzymatic method for measuring serum mevalonic acid (MVA) concentration, which is thought to be a good indicator of the in vivo cholesterol biosynthesis rate.
Takeshi Matsuoka   +3 more
doaj   +2 more sources

Case Report: Early-onset mevalonic aciduria in neonates with inflammatory marker elevated [PDF]

open access: yesFrontiers in Immunology
PurposeThe aim of this study was to present a case of early-onset mevalonic aciduria (MA) in a neonate and summarize the relevant phenotypic and genotypic spectra of MA.Methods and resultsWe describe a neonate who presented with elevated inflammatory ...
Shanshan Xue   +7 more
doaj   +2 more sources

A Distinct Phenotype of Mevalonic Acidemia with Absence of Pathogenic Mutations of Mevalonate Kinase Gene [PDF]

open access: yesمجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2016
Mevalonic aciduria is an autosomal recessive disorder caused by deficiency of mevalonate kinase and characterized by recurrent febrile crisis, ophthalmic and neurological manifestations.
Imad Dweikat, Nadera Damsa, Enas Naser
doaj   +1 more source

Production of Mevalonic Acid by Fermentation [PDF]

open access: yesApplied Microbiology, 1968
The purpose of this investigation was to select microorganisms that produce substantial quantities of mevalonic acid and to develop an economic fermentation process. To screen for mevalonic acid-producing microorganisms, it was necessary to improve the method for the quantitative determination of this acid.
G, Tamura, K, Ando, K, Kodama, K, Arima
openaire   +2 more sources

Bacterial Metabolism of Mevalonic Acid [PDF]

open access: yesJournal of Bacteriology, 1967
Soluble cell-free extracts of actinomycete S4 grown on media containing mevalonate catalyze acetoacetate formation from mevalonate, mevaldate, and β-hydroxy-β-methylglutaryl-coenzyme A (CoA). Conversion of mevalonate to acetoacetate involves formation of free β-hydroxy-β-methylglutaryl-CoA, but not free mevaldate.
M A, Siddiqi, V W, Rodwell
openaire   +2 more sources

Mevalonate metabolism by renal tissue in vitro

open access: yesJournal of Lipid Research, 1974
Previous studies from this laboratory have demonstrated that the kidneys rather than the liver play the major role in the in vivo metabolism of circulating mevalonic acid.
Philip Raskin, Marvin D. Siperstein
doaj   +1 more source

Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis

open access: yesJournal of Lipid Research, 1996
Urinary excretion of mevalonic acid was investigated as an indicator of cholesterol synthesis. In normolipemic volunteers, excretion of mevalonic acid averaged 3.51 +/- 0.59 (SD) micrograms/kg x day1; (n = 24) and was not different from patients with ...
B Lindenthal   +5 more
doaj   +1 more source

INFLUENCE OF MEVALONIC ACID AND LINALOOL ON LIMONENE ACCUMULATION IN CALLUS TISSUES OF CITRUS GRANDIS OSBECK

open access: yesBiotropia: The Southeast Asian Journal of Tropical Biology, 2011
Effect on callus growth was studied for Citrus grandis  cultured with feeding of exogenous mevalonic acid (MVA) at concentrations of 0.04, 0.08, 0.38, 0.77, 1.15 and 1.54 mM.
ZARINA ZAKARIA   +2 more
doaj   +1 more source

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