Results 21 to 30 of about 6,314 (218)

Studies on a mevaldic acid reductase of rat liver*

open access: yesJournal of Lipid Research, 1962
A TPNH-specific mevaldic reductase of rat liver has been partially purified. This enzyme fraction catalyzes the reduction of both optical isomers of mevaldic acid to isomeric mevalonic acids.
Harold J. Knauss   +2 more
doaj   +1 more source

EFFECTS OF STATINS UPON ANTIGEN-SPECIFIC LYMPHOCYTE ACTIVATION IN PATIENTS WITH RHEUMATOID ARTHRITIS: AN IN VITRO STUDY

open access: yesМедицинская иммунология, 2014
. Collagen type II (Col II) is among the proposed candidate autoantigens initiaiting rheumatoid arthritis (RA). Statins have been shown to have anti-inflammatory and immunomodulating properties. Mechanisms of statin effects upon the autoantigen-induced T
I. V. Shirinsky, V. S. Shirinsky
doaj   +1 more source

Autoinflammatory disease syndrome of hyperimmunoglobulinemia D

open access: yesМедицинский вестник Юга России, 2022
Objective: present a clinical case of a rare autoinflammatory disease. Materials and methods: an analysis of a clinical case of mevalonate kinase deficiency syndrome in an 8-year-old girl was carried out.
T. M. Somova
doaj   +1 more source

Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta

open access: yesJournal of Lipid Research, 1973
Homogenates and subcellular fractions of the intima–media of hog aorta have been prepared and examined for the presence of the enzymes catalyzing the conversion of acetyl CoA to squalene.
Linda L. Slakey   +3 more
doaj   +1 more source

Radioautographic visualization of incorporation of lipid precursors into anthers of Muscari comosum (L.) Mili.

open access: yesActa Societatis Botanicorum Poloniae, 2015
Incorporation of the following lipid precursors: DL-mevalonic acid-2 3H, 3H palmitic acid and acetic acid-3H sodium salt, into the anther cells of Muscari comosum (L.) Mili. has been investigated.
Barbara Gabara
doaj   +1 more source

Biosynthesis of cholesterol in rabbit reticulocytes and its exchange with plasma

open access: yesJournal of Lipid Research, 1970
When rabbit reticulocytes were incubated in normal blood plasma containing mevalonic acid-2-(14)C, radioactivity was incorporated into cholesterol, cholesteryl esters, and squalene in the cells.
H.A. Sloviter, V. Janic, T. Cirkovic
doaj   +1 more source

Chromatographic separation of allylic alcohols on silicic acid columns: Analysis of the nonsaponifiable lipids of an ascites tumor derived from a benzpyrene-induced sarcoma

open access: yesJournal of Lipid Research, 1963
Chromatographic separations of dimethyl allyl alcohol, geraniol, nerol, nerolidol, and trans-trans-farnesol were achieved on silicic acid-Super Cel columns.
George J. Schroepfer, Jr.   +1 more
doaj   +1 more source

Ribonuclease Inhibition of Mevalonic Acid Utilization.

open access: yesExperimental Biology and Medicine, 1958
SummaryUtilization of mevalonic acid as determined by incorporation of the 2-C14-labeled compound into non-saponifiable material or into cholesterol or by disappearance of microbiological activity attributable to mevalonic acid in rat liver homogenates was found to be abolished by a preliminary digestion with ribonuclease.
L D, WRIGHT, M, CLELAND, B N, DUTTA
openaire   +2 more sources

Decreased production of low density lipoprotein by atorvastatin after apheresis in homozygous familial hypercholesterolemia

open access: yesJournal of Lipid Research, 1997
Apheresis only partially controls raised low density lipoprotein cholesterol levels in patients with homozygous familial hypercholesterolemia, who usually respond poorly to lipid-lowering drugs.
A D Marais   +5 more
doaj   +1 more source

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved

open access: yesViruses, 2021
Statin derivatives can inhibit the replication of a range of viruses, including hepatitis C virus (HCV, Hepacivirus), dengue virus (Flavivirus), African swine fever virus (Asfarviridae) and poliovirus (Picornaviridae).
Fauziah Mohd Jaafar   +4 more
doaj   +1 more source

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