Results 21 to 30 of about 10,880 (220)
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]
, 2004 Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S. +5 more
core +1 more source
Studies on a mevaldic acid reductase of rat liver*
Journal of Lipid Research, 1962 A TPNH-specific mevaldic reductase of rat liver has been partially purified. This enzyme fraction catalyzes the reduction of both optical isomers of mevaldic acid to isomeric mevalonic acids.
Harold J. Knauss +2 more
doaj +1 more source
Медицинская иммунология, 2014 . Collagen type II (Col II) is among the proposed candidate autoantigens initiaiting rheumatoid arthritis (RA). Statins have been shown to have anti-inflammatory and immunomodulating properties. Mechanisms of statin effects upon the autoantigen-induced T
I. V. Shirinsky, V. S. Shirinsky
doaj +1 more source
Autoinflammatory disease syndrome of hyperimmunoglobulinemia D
Медицинский вестник Юга России, 2022 Objective: present a clinical case of a rare autoinflammatory disease. Materials and methods: an analysis of a clinical case of mevalonate kinase deficiency syndrome in an 8-year-old girl was carried out.
T. M. Somova
doaj +1 more source
Quantification of Urinary Mevalonic Acid as a Biomarker of HMG-CoA Reductase Activity by a Novel Translational LC-MS/MS Method [PDF]
, 2014 Background: Mevalonic acid (MVA), as a product of 3-hydroxy-3-methylglutaryl coenzyme A reductase, represents a potential multipurpose biomarker in health and disease. A translational urinary MVA quantification method was developed, validated and used to
Antoine, Daniel J +7 more
core +1 more source
Journal of Lipid Research, 1973 Homogenates and subcellular fractions of the intima–media of hog aorta have been prepared and examined for the presence of the enzymes catalyzing the conversion of acetyl CoA to squalene.
Linda L. Slakey +3 more
doaj +1 more source
Ribonuclease Inhibition of Mevalonic Acid Utilization.
Experimental Biology and Medicine, 1958 SummaryUtilization of mevalonic acid as determined by incorporation of the 2-C14-labeled compound into non-saponifiable material or into cholesterol or by disappearance of microbiological activity attributable to mevalonic acid in rat liver homogenates was found to be abolished by a preliminary digestion with ribonuclease.
L D, WRIGHT, M, CLELAND, B N, DUTTA
openaire +2 more sources
Acta Societatis Botanicorum Poloniae, 2015 Incorporation of the following lipid precursors: DL-mevalonic acid-2 3H, 3H palmitic acid and acetic acid-3H sodium salt, into the anther cells of Muscari comosum (L.) Mili. has been investigated.
Barbara Gabara
doaj +1 more source
Experimental Biology and Medicine, 1961 SummarySynthetic isovalthine (S-(isopropyl-carboxymethyl)-cysteine) was added to urine from hypercholesterolemic patients that had received mevalonic acid-2-C14 intravenously. Isovalthine recovered from the urine was found to be devoid of radioactivity thus indicating that either (a) mevalonic acid is not a precursor of isovalthine, or (b) mevalonic ...
L D, WRIGHT, W P, HOLLANDER
openaire +2 more sources
Biosynthesis of cholesterol in rabbit reticulocytes and its exchange with plasma
Journal of Lipid Research, 1970 When rabbit reticulocytes were incubated in normal blood plasma containing mevalonic acid-2-(14)C, radioactivity was incorporated into cholesterol, cholesteryl esters, and squalene in the cells.
H.A. Sloviter, V. Janic, T. Cirkovic
doaj +1 more source