Results 41 to 50 of about 6,314 (218)
Probing cataractogenesis associated with mevalonic aciduria
, 1998 Purpose. Mevalonic aciduria in humans results from a genetic deficiency of mevalonate kinase and is characterized by very high plasma mevalonic acid levels, developmental malformations and cataracts.
Cenedella, Richard J. +1 more
core +1 more source
METABOLISM OF MEVALONIC ACID BY LACTOBACILLUS PLANTARUM [PDF]
Journal of Bacteriology, 1964 Durr , I. F. (American University of Beirut, Beirut, Lebanon), and A. N. Shwayri . Metabolism of mevalonic acid by Lactobacillus plantarum . J. Bacteriol. 88: 361–366. 1964.— Lactobacillus plantarum strain 8014-H 2
I F, DURR, A N, SHWAYRI
openaire +2 more sources
Acta Societatis Botanicorum Poloniae, 2015 Tecoma stans Juss. callus tissue grown on Murashige-Mei Lie Lin (M-L) and Murashige-Skoog (RT-k) medium supplemented with Tecoma alkaloid precursors like lysine, mevalonic acid lactone and quinolinic acid, were investigated for their alkaloid content by ...
Barbara Dohnal
doaj +1 more source
Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome
Orphanet Journal of Rare Diseases, 2006 Mevalonic aciduria (MVA) and hyperimmunoglobulinemia D syndrome (HIDS) represent the two ends of a clinical spectrum of disease caused by deficiency of mevalonate kinase (MVK), the first committed enzyme of cholesterol biosynthesis.
Hoffmann Georg F, Haas Dorothea
doaj +1 more source
Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host
Reviews in Medical Virology, Volume 36, Issue 4, July 2026.ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini +4 more
wiley +1 more source
Diastereoselective and enantioselective preparation of nor-mevaldic acid surrogates through desymmetrisation methodology. Enantioselective synthesis of (+) and (-) nor-mevalonic lactones [PDF]
, 2015 Solvent-free desymmetrisation of a meso-dialdehyde with chiral alcohols, led to preparation of 4-silyloxy-6-alkyloxytetrahydro-2H-pyran-2-one derivatives with a 96% de.
Macías-Sánchez, Antonio José +11 more
core +1 more source
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.L‐malic acid, a natural TCA cycle intermediate, attenuates the virulence of Staphylococcus aureus through dual metabolic and regulatory mechanisms. It redirects central carbon flux away from the mevalonate pathway and inhibits the key enzyme CrtO, suppressing staphyloxanthin biosynthesis and impairing bacterial resistance to oxidative stress ...
Li Shen +11 more
wiley +1 more source
Journal of Lipid Research, 1980 Highly purified human granulocytes synthesize [14C]farnesol and [14C]squalene but not [14C]sterols from [14C]mevalonic acid. Dimethylsulfoxide was found to be an excellent vehicle for carrying [3H]squalene-2, 3-oxide into the intact cells.
I Shechter, A M Fogelman, G Popják
doaj +1 more source
New Phytologist, Volume 250, Issue 5, Page 2966-2987, June 2026.Summary The oleoresin defense system of loblolly pine (Pinus taeda) protects trees from insects and pathogens and is an important source of renewable biofuels and chemicals, but the genetic basis of oleoresin production is poorly understood. We characterized the genetic architecture of oleoresin flow, resin canal number, stem wood terpene content, and ...
Mallory M. Morgan +13 more
wiley +1 more source
Diverse genetic error modes constrain large-scale bio-based production
Nature Communications, 2018 The declining performance of scale-up bioreactor cultures is commonly attributed to phenotypic and physical heterogeneities. Here, the authors reveal multiple recurring intra-pathway error modes that limit engineered E.
Peter Rugbjerg +4 more
doaj +1 more source