Results 51 to 60 of about 6,314 (218)

Ent-homocyclopiamine B, a Prenylated Indole Alkaloid of Biogenetic Interest from the Endophytic Fungus Penicillium concentricum

Molecules, 2019
Ent-homocyclopiamine B (1), a new prenylated indole alkaloid bearing an alicyclic nitro group along with 2-methylbutane-1,2,4-triol (2) were isolated from an endophytic fungus Penicillium concentricum of the liverwort Trichocolea tomentella ...
Tehane Ali, Tiffany M. Pham, Kou-San Ju, Harinantenaina L. Rakotondraibe   +3 more
doaj   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4204-4220, June 2026.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts [PDF]

, 2012
Background Carotenoids are the most widespread group of pigments found in nature. In addition to their role in the physiology of the plant, carotenoids also have nutritional relevance as their incorporation in the human diet provides health benefits.
Pateraki, Irini, Boronat Albert, Rocco Petrizzo, Boronat, Albert, Pateraki, Irene, Albert Boronat, Busquets, Montserrat, Pateraki Irene, Boronat i Margosa, Albert, Hernández-Gras Francesc, Irene Pateraki, Francesc Hernández-Gras, Carmen Romero-Segura, Djédoux Angaman, Montserrat Busquets, Angaman, Djedoux Maxime, Petrizzo Rocco, Busquets Montserrat, Busquets Abió, Montserrat, Romero-Segura, Carmen, Angaman Djédoux, Hernández-Gras, Francesc, Hernández Gras, Francesc, Petrizzo, Rocco, Romero Segura, Carmen, Romero-Segura Carmen   +25 more
core   +1 more source

Turnover of cholesteryl esters of plasma lipoproteins in the rat

Journal of Lipid Research, 1967
Turnover of individual classes of cholesteryl esters (classified on the basis of the degree of unsaturation of the fatty acid moiety) in rat plasma lipoproteins and liver was studied after the administration of mevalonic acid-5-3H and mevalonic acid-2 ...
Lewis I. Gidez, Paul S. Roheim, Howard A. Eder   +2 more
doaj   +1 more source

Preoperative Beta‐Hydroxy‐Beta‐Methyl‐Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
A. L. Vieira‐da‐Silva, M. V. Esteca, F. A. Silva, I. A. Divino, F. S. Carneiro, E. R. Ropelle, A. S. Torsoni, I. L. Baptista   +7 more
wiley   +1 more source

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

, 2012
Microbial production can be advantageous over the extraction of phytoterpenoids from natural plant sources, but it remains challenging to rationally and rapidly access efficient pathway variants.
Jin, Guojie, HuangLuqi, Zhou, Yongjin J., Zhu, Zhiwei, Gao, Wei, Chu, Huiying, Li, Guohui, Liu, Wujun, Yang, Wei, Huang, Luqi, Zhao, Zongbao K., Rong, Qixian, Zhu, Guofeng   +12 more
core   +1 more source

Acceleration of hepatic sterol synthesis after a single dose of the porphyrogenic chemical allylisopropylacetamide

Journal of Lipid Research, 1974
Hepatic sterol synthesis is accelerated in animals after a single dose of allylisopropylacetamide, a chemical known to be porphyrogenic. Evidence is provided to show that enhanced sterol biosynthesis is due to an increased formation of mevalonic acid ...
Luigi Taddeini, Ivan Frantz, Jr., Ajit Sanghvi   +2 more
doaj   +1 more source

Environmental Circulation of Aspergillus fumigatus With Reduced Susceptibility to Agricultural Triazole in Brazil: Clonal Dissemination of Potentially Resistant Genotypes

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Aspergillus fumigatus resistance to triazole antifungals poses an increasing global health concern. Moreover, the cross‐resistance between azole antifungal agents used in clinical settings and those applied in agriculture has become an important emerging issue.
Dality Keffelen de Barros Rodrigues, Manuel Leeuwerik, Balázs Brankovics, Wellington Santos Fava, James Venturini, Wieland Meyer, Teppei Arai, Hidetaka Majima, Akira Watanabe, Marcia de Souza Carvalho Melhem   +9 more
wiley   +1 more source

EnzRetro: Enzymatic Retrosynthetic Planning With Site‐Specific Reaction Edits Based on Sequence Generative Architecture

Exploration, Volume 6, Issue 2, April 2026.
EnzRetro bridges retrosynthesis planning and enzymatic engineering through site‐specific reaction edits. This end‐to‐end framework integrates pathway synthesis and enzyme identification into a unified process, achieving superior accuracy and enabling the efficient reconstruction of diverse biosynthetic pathways.
Yahui Cao, Haoshu Chen, Tao Zhang, Xin Zhao, Bingzhi Li, Xiangrui Zheng   +5 more
wiley   +1 more source

Cell density dependent uptake of chylomicron remnants in rat hepatocyte monolaayers. Effects of compactin and mevalonic acid.

, 1987
In rat hepatocytes cultured in lipoprotein-deficient serum, the uptake and degradation of chylomicron remnant cholesteryl ester per mg cell protein varies inversely with cell density.
Florén, Claes-Henrik, Jensen, Elmo, Nilsson, Åke   +2 more
core   +2 more sources