Results 61 to 70 of about 5,897 (180)

Preoperative Beta‐Hydroxy‐Beta‐Methyl‐Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice

open access: yesActa Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
A. L. Vieira‐da‐Silva   +7 more
wiley   +1 more source

Environmental Circulation of Aspergillus fumigatus With Reduced Susceptibility to Agricultural Triazole in Brazil: Clonal Dissemination of Potentially Resistant Genotypes

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Aspergillus fumigatus resistance to triazole antifungals poses an increasing global health concern. Moreover, the cross‐resistance between azole antifungal agents used in clinical settings and those applied in agriculture has become an important emerging issue.
Dality Keffelen de Barros Rodrigues   +9 more
wiley   +1 more source

Molecular Characterization of Trypanosoma evansi Mevalonate Kinase (TeMVK)

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The mevalonate pathway is an essential part of isoprenoid biosynthesis leading to production of a diverse class of >30,000 biomolecules including cholesterol, heme, and all steroid hormones.
Daniel P. Duarte   +8 more
doaj   +1 more source

EnzRetro: Enzymatic Retrosynthetic Planning With Site‐Specific Reaction Edits Based on Sequence Generative Architecture

open access: yesExploration, Volume 6, Issue 2, April 2026.
EnzRetro bridges retrosynthesis planning and enzymatic engineering through site‐specific reaction edits. This end‐to‐end framework integrates pathway synthesis and enzyme identification into a unified process, achieving superior accuracy and enabling the efficient reconstruction of diverse biosynthetic pathways.
Yahui Cao   +5 more
wiley   +1 more source

Metabolic engineering of Escherichia coli for the utilization of ethanol

open access: yesJournal of Biological Research - Thessaloniki, 2020
Background The fuel ethanol industry has made tremendous progress in the last decades. Ethanol can be obtained by fermentation using a variety of biomass materials as the feedstocks.
Yujin Cao   +7 more
doaj   +1 more source

A Plant‐Based Platform for the Production of Bark Beetle Pheromones

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 2442-2456, April 2026.
ABSTRACT Bark beetle species of the genera Ips and Dendroctonus represent a threat to forests in both North America and Europe. Under normal circumstances, these beetles recycle dying trees into nutrients, but under certain conditions, growing populations can overcome healthy tree defenses and cause severe economic loss in forestry.
Abraham Ontiveros‐Cisneros   +7 more
wiley   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, Volume 4, Issue 1, March 2026.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

CHEMICAL INDEXES CALCULATED FOR 8,11,13-TRIENABIETANE DITERPENOIDS ISOLATED FROM SWARTZIA SPECIES

open access: yesEclética Química, 2018
The disparity found in the molecular structures of compounds isolated from nine plants of the Swartzia genus indicates that the Swartzia species that furnished cassane diterpenoids and triterpenoidal saponins are more recent, since these metabolites have
Aderbal Farias Magalhães   +3 more
doaj   +1 more source

Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin

open access: yesJournal of Lipid Research, 1997
HMG-CoA reductase inhibitors or statins are effective in both the primary and secondary prevention of coronary heart disease, the extent of benefit being proportional to the reduction in low density lipoprotein (LDL) cholesterol achieved. Atorvastatin, a
R P Naoumova   +7 more
doaj   +1 more source

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