Results 71 to 80 of about 5,602 (181)
BMEMat, Volume 4, Issue 1, March 2026.The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang +7 more
wiley +1 more source
Molecular Characterization of Trypanosoma evansi Mevalonate Kinase (TeMVK)
Frontiers in Cellular and Infection Microbiology, 2018 The mevalonate pathway is an essential part of isoprenoid biosynthesis leading to production of a diverse class of >30,000 biomolecules including cholesterol, heme, and all steroid hormones.
Daniel P. Duarte +8 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.ABSTRACT In this study, bioassay‐guided fractionation of the ethanolic extract from Eremanthus crotonoides leaves enabled the isolation of two bioactive sesquiterpene lactones, centratherin and goyazensolide, which were evaluated for their antimycobacterial and anti‐inflammatory properties.
Natalie Giovanna da Rocha Ximenes +7 more
wiley +1 more source
Metabolic engineering of Escherichia coli for the utilization of ethanol
Journal of Biological Research - Thessaloniki, 2020 Background The fuel ethanol industry has made tremendous progress in the last decades. Ethanol can be obtained by fermentation using a variety of biomass materials as the feedstocks.
Yujin Cao +7 more
doaj +1 more source
Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi +2 more
wiley +1 more source
New Zealand Journal of Marine and Freshwater Research, Volume 60, Issue 1, March 2026.Green‐lipped mussel (Perna canaliculus) aquaculture is vulnerable to environmental changes, which are increasingly being studied to pinpoint physiological, economic and ecological threats. This study utilised a targeted liquid chromatography‐mass spectrometry metabolomics approach, focusing on the central carbon metabolism, to examine the metabolic ...
Leonie Venter +6 more
wiley +1 more source
CHEMICAL INDEXES CALCULATED FOR 8,11,13-TRIENABIETANE DITERPENOIDS ISOLATED FROM SWARTZIA SPECIES
Eclética Química, 2018 The disparity found in the molecular structures of compounds isolated from nine plants of the Swartzia genus indicates that the Swartzia species that furnished cassane diterpenoids and triterpenoidal saponins are more recent, since these metabolites have
Aderbal Farias Magalhães +3 more
doaj +1 more source
Chemistry of mevalonic acid [PDF]
Biochemical Journal, 1969 J W, Cornforth, R H, Cornforth
openaire +3 more sources
Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin
Journal of Lipid Research, 1997 HMG-CoA reductase inhibitors or statins are effective in both the primary and secondary prevention of coronary heart disease, the extent of benefit being proportional to the reduction in low density lipoprotein (LDL) cholesterol achieved. Atorvastatin, a
R P Naoumova +7 more
doaj +1 more source
THE BIOSYNTHESIS OF MEVALONIC ACID [PDF]
Proceedings of the National Academy of Sciences, 1959 J J, Ferguson, I F, Durr, H, Rudney
openaire +2 more sources