Results 11 to 20 of about 6,314 (218)
Effect on callus growth was studied for Citrus grandis cultured with feeding of exogenous mevalonic acid (MVA) at concentrations of 0.04, 0.08, 0.38, 0.77, 1.15 and 1.54 mM.
ZARINA ZAKARIA +2 more
doaj +3 more sources
Mevalonic Acid as A Precursor in the Biogenesis of Digitoxigenin
Abstract (±)-Mevalonic acid-2-14C has been injected into a growing plant of Digitalis lanata L. to test if this acid serves as a precursor in the biosynthesis of cardenolides. After nine days a portion of the leaves was extracted and the constituents submitted to paper chromatography followed by autoradiography.
E, RAMSTAD, J L, BEAL
openaire +3 more sources
Priming by Hexanoic acid induce activation of mevalonic and linolenic pathways and promotes the emission of plant volatiles. [PDF]
Hexanoic acid is a short natural monocarboxylic acid present in some fruits and plants. Previous studies reported that soil drench application of this acid induces effective resistance in tomato plants against Botrytis cinerea and Pseudomonas syringae ...
Eugenio eLlorens +3 more
doaj +2 more sources
Effect on callus growth was studied for Citrus grandis cultured with feeding of exogenous mevalonic acid (MVA) at concentrations of 0.04, 0.08, 0.38, 0.77, 1.15 and 1.54 mM.
ZARINA ZAKARiA +2 more
doaj +2 more sources
Diagnostic Value of Urinary Mevalonic Acid Excretion in Patients with a Clinical Suspicion of Mevalonate Kinase Deficiency (MKD). [PDF]
In patients suffering from mevalonate kinase deficiency (MKD), the reduced enzyme activity leads to an accumulation of mevalonic acid which is excreted in the urine.
Jeyaratnam J +5 more
europepmc +2 more sources
missense variants in mevalonic aciduria [PDF]
Mevalonic aciduria (MVA) and hyperimmunoglobulinemia D syndrome (MKD/HIDS) are disorders of cholesterol biosynthesis caused by variants in the MVK gene and characterized by increased urinary excretion of mevalonic acid.
Martini, S. +31 more
core +2 more sources
HMGCS1 variants cause rigid spine syndrome amenable to mevalonic acid treatment in an animal model. [PDF]
The data and constructs generated by this study are available upon request. Zebrafish experiment data are available from the Monash University Bridges data repository (https://doi.org/10.26180/c.7354282).Rigid spine syndrome is a rare childhood-onset ...
Dofash LNH +40 more
europepmc +2 more sources
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K. +5 more
core +1 more source
Inhibition of cholesterol biogenesis by arsenite: preparation of labeled lanosterol*
When mevalonic acid-2-C14 was incubated with rat liver homogenate with the usual cofactors plus 10−3 M arsenite, the formation of labeled cholesterol was inhibited and labeled lanosterol accumulated.
Mary L. Moller, T.T. Tchen
doaj +1 more source
SummarySynthetic isovalthine (S-(isopropyl-carboxymethyl)-cysteine) was added to urine from hypercholesterolemic patients that had received mevalonic acid-2-C14 intravenously. Isovalthine recovered from the urine was found to be devoid of radioactivity thus indicating that either (a) mevalonic acid is not a precursor of isovalthine, or (b) mevalonic ...
L D, WRIGHT, W P, HOLLANDER
openaire +2 more sources

