Results 11 to 20 of about 5,897 (180)

Multi-Target Anti-Obesity Potential of <i>Coula edulis</i> Nut Extract in High-Fat Diet-Induced Obesity in Rats. [PDF]

open access: yesFood Sci Nutr
This study evaluated the multi‐target anti‐obesity effects of Coula edulis nut extract (CEE) in high‐fat diet‐induced obese Wistar rats. Following 4 weeks of obesity induction, rats received oral CEE at 1 or 2 g/kg body weight, or orlistat for 5 weeks under continued high‐fat diet or normal diet conditions.
Ibeneme CE   +9 more
europepmc   +2 more sources

Production of Mevalonic Acid by Fermentation [PDF]

open access: yesApplied Microbiology, 1968
The purpose of this investigation was to select microorganisms that produce substantial quantities of mevalonic acid and to develop an economic fermentation process. To screen for mevalonic acid-producing microorganisms, it was necessary to improve the method for the quantitative determination of this acid.
G, Tamura, K, Ando, K, Kodama, K, Arima
openaire   +2 more sources

Bacterial Metabolism of Mevalonic Acid [PDF]

open access: yesJournal of Bacteriology, 1967
Soluble cell-free extracts of actinomycete S4 grown on media containing mevalonate catalyze acetoacetate formation from mevalonate, mevaldate, and β-hydroxy-β-methylglutaryl-coenzyme A (CoA). Conversion of mevalonate to acetoacetate involves formation of free β-hydroxy-β-methylglutaryl-CoA, but not free mevaldate.
M A, Siddiqi, V W, Rodwell
openaire   +2 more sources

Urinary Metabolites of Mevalonic Acid: Evidence That Mevalonic Acid is not a Precursor of Isovalthine

open access: yesExperimental Biology and Medicine, 1961
SummarySynthetic isovalthine (S-(isopropyl-carboxymethyl)-cysteine) was added to urine from hypercholesterolemic patients that had received mevalonic acid-2-C14 intravenously. Isovalthine recovered from the urine was found to be devoid of radioactivity thus indicating that either (a) mevalonic acid is not a precursor of isovalthine, or (b) mevalonic ...
L D, WRIGHT, W P, HOLLANDER
openaire   +2 more sources

Studies on a mevaldic acid reductase of rat liver*

open access: yesJournal of Lipid Research, 1962
A TPNH-specific mevaldic reductase of rat liver has been partially purified. This enzyme fraction catalyzes the reduction of both optical isomers of mevaldic acid to isomeric mevalonic acids.
Harold J. Knauss   +2 more
doaj   +1 more source

EFFECTS OF STATINS UPON ANTIGEN-SPECIFIC LYMPHOCYTE ACTIVATION IN PATIENTS WITH RHEUMATOID ARTHRITIS: AN IN VITRO STUDY

open access: yesМедицинская иммунология, 2014
. Collagen type II (Col II) is among the proposed candidate autoantigens initiaiting rheumatoid arthritis (RA). Statins have been shown to have anti-inflammatory and immunomodulating properties. Mechanisms of statin effects upon the autoantigen-induced T
I. V. Shirinsky, V. S. Shirinsky
doaj   +1 more source

Autoinflammatory disease syndrome of hyperimmunoglobulinemia D

open access: yesМедицинский вестник Юга России, 2022
Objective: present a clinical case of a rare autoinflammatory disease. Materials and methods: an analysis of a clinical case of mevalonate kinase deficiency syndrome in an 8-year-old girl was carried out.
T. M. Somova
doaj   +1 more source

Biosynthesis of Abscisic Acid by the Non-mevalonate Pathway in Plants, and by the Mevalonate Pathway in Fungi [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 2000
The biosynthetic pathways to abscisic acid (ABA) were investigated by feeding [1-(13)C]-D-glucose to cuttings from young tulip tree shoots and to two ABA-producing phytopathogenic fungi. 13C-NMR spectra of the ABA samples isolated showed that the carbons at 1, 5, 6, 4', 7' and 9' of ABA from the tulip tree were labeled with 13C, while the carbons at 2,
HIRAI, Nobuhiro   +3 more
openaire   +2 more sources

Occurrence of the enzymes effecting the conversion of acetyl CoA to squalene in homogenates of hog aorta

open access: yesJournal of Lipid Research, 1973
Homogenates and subcellular fractions of the intima–media of hog aorta have been prepared and examined for the presence of the enzymes catalyzing the conversion of acetyl CoA to squalene.
Linda L. Slakey   +3 more
doaj   +1 more source

Radioautographic visualization of incorporation of lipid precursors into anthers of Muscari comosum (L.) Mili.

open access: yesActa Societatis Botanicorum Poloniae, 2015
Incorporation of the following lipid precursors: DL-mevalonic acid-2 3H, 3H palmitic acid and acetic acid-3H sodium salt, into the anther cells of Muscari comosum (L.) Mili. has been investigated.
Barbara Gabara
doaj   +1 more source

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