Jurnal Ilmu Kesehatan Indonesia, 2022 Background. Brain edema is swelling in the brain due to excessive accumulation of fluid in the brain. This condition is triggered by a decrease in cerebral blood flow (CBF) due to heart damage or isoproterenol administraion.
Muhammad Arief Ansyar +2 more
doaj +1 more source
β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]
, 2014 Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L +5 more
core +3 more sources
Alterations of medial prefrontal cortex bioelectrical activity in experimental model of isoprenaline-induced myocardial infarction [PDF]
, 2020 Background Clinical and animal studies have found that anxiety and depression are significantly more common after acute myocardial infarction (AMI).
Hrnčić, Dragan +7 more
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Current Issues in Molecular Biology, 2022 Therapeutic and/or preventive interventions using phytochemical constituents for ischemic heart disease have gained considerable attention worldwide, mainly due to their antioxidant activity.
Taseer Ahmad +9 more
doaj +1 more source
Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes
PLoS ONE, 2015 Beta-adrenergic activation stimulates uncoupling protein 1 (UCP1), enhancing metabolic rate. In vitro, most work has studied brown adipocytes, however, few have investigated more established adipocyte lines such as the murine 3T3-L1 line.
C. Miller +5 more
semanticscholar +1 more source
The Egyptian Heart Journal, 2012 Objectives: In recent years, fucoidan is being marketed as a nutraceutical and food supplement because of its various pharmacological activity.
Krishnamoorthy Mohankumar +3 more
doaj +1 more source
Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production [PDF]
, 2018 The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown to counter experimental HF, including doxorubicin cardiotoxicity (a condition characterized by ...
Carlo G. Tocchetti +16 more
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Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
Advanced Healthcare Materials, EarlyView.We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
Biology, 2020 Cardiotoxicity remains a challenging concern both in drug development and in the management of various clinical situations. There are a lot of examples of drugs withdrawn from the market or stopped during clinical trials due to unpredicted cardiac ...
Matthieu Dallons +4 more
doaj +1 more source
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells - Activation of protein kinase B by wortmannin-sensitive and -insensittve mechanisms [PDF]
, 1997 Previous studies using L6 myotubes have suggested that glycogen synthase kinase-3 (GSK-3) is phosphoryl ated and inactivated in response to insulin by protein kinase B (PKB, also known as Akt or RAG) (Cross, D, A, E., Alessi, D, R., Cohen, P ...
Denton, Richard M. +5 more
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