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ChemInform Abstract: Synthesis of Benzimidazo(2,1‐a)isoquinolines and 5,6‐ Dihydrobenzimidazo(2,1‐a)isoquinolines.

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Qun Sun, Edmond J. LaVoie
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Cyanochlorination and cyanation of isoquinolines

Journal of the Chemical Society, Perkin Transactions 1, 1979
Treatment of isoquinoline with sulphuryl chloride and potassium cyanide gave, in one preparative step, 4-chloro-1-cyanoisoquinoline and 1-carbamoyl-3-cyanoisoquinoline in yields dependent upon the proportions of reagents. 4-Chloroisoquinoline, 1,3-dicyanoisoquinoline, 3-cyanoisoquinoline, and 1-cyanoisoquinoline were also produced under different ...
Seng Leong Tan   +2 more
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Jet spectroscopy of isoquinoline

Chemical Physics Letters, 1983
The jet-cooled spectra of isoquinoline and an isoquinoline-methanol complex are reported. The lifetimes, dispered fluorescence and excitation spectra are all discussed in terms of excited state interactions. Methanol complexation is found to be a useful probe of excited state level structure and dynamics.
Felker, Peter M., Zewail, Ahmed H.
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Isoquinoline and its derivatives

1991
Publisher Summary This chapter covers the chemistry on isoquinoline for the period of 10 years (1985 to 1995). Excellent reviews are published for isoquinoline chemistry, the structure, reactivity, and synthesis of some isoquinolines and hydroisoquinolines that have been reviewed under pyridines and their benzo derivatives in a more concise form in ...
Marudai Balasubramanian   +1 more
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Pictet–Gams isoquinoline synthesis

2002
The isoquinoline framework is derived from the corresponding acyl derivatives of β-hydroxy-β-phenylethylamines. Upon exposure to a dehydrating agent such as phosphorus pentoxide, or phosphorus oxychloride, under reflux and in an inert solvent such as decalin, isoquinoline frameworks are formed.
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The reductive alkylation of isoquinoline

Journal of the Chemical Society C: Organic, 1966
Reductive alkylation of isoquinoline with benzaldehyde in acetic acid gives a mixture of 2-benzyl-, 4-benzyl-, and 2,4-dibenzyl-1,2,3,4-tetrahydroisoquinolines and 4-benzylisoquinoline. Contrary to earlier reports, the major product is 2-benzyl-1,2,3,4-tetrahydroisoquinoline, not the 4-isomer.
P. Garside, A. C. Ritchie
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The Biosynthesis of Isoquinoline Alkaloids

1985
The tetrahydroisoquinoline skeleton occurs in numerous plant alkaloids. The simplest bearers of this structural unit are exemplified by anhalonidine (12) (Sect. 2). Slightly more elaborate are the benzylisoquinoline alkaloids exemplified at their simplest by reticuline (25) and papaverine (27) (Sect. 3).
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Some Substituted Isoquinolines

Journal of the American Chemical Society, 1947
Henry Gilman, Gordon C. Gainer
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Isoquinolines in Parkinson’s Disease

2000
1,2,3,4-Tetrahydroisoquinoline (TIQ) derivatives, which chemically resemble MPTP, exist in mammals and have been proposed as candidates for endogenous parkinsonogenic compounds. TIQ, l-benzyl-l,2,3,4-tetrahydroisoquinoline (1-benzyl-TIQ) could induce parkinsonism in rodents and a primate.
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Isoquinoline Alkaloids and Chemotaxonomy

2019
The isoquinoline alkaloids are a class of secondary metabolites classified into different groups, being the aporphinoids the most representative class. They are considered the second-largest class of alkaloids in terms of structural diversity staying behind only of indole alkaloids.
Nelissa P. Vaz   +1 more
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