Results 11 to 20 of about 7,392 (228)
Two mutually complementary synthetic approaches towards 3-substituted 3,4-disubstituted and 1-(2-pyridyl)-substituted isoquinolines [PDF]
Two mutually complementary synthetic approaches towards 3- and 3,4-disubstituted 1-(2-pyridyl) isoquinolines were studied. The aryne-based method was successfully used for the obtaining of the corresponding the 3-cyano-1-(2-pyridyl)isoquinolines in one ...
I. L. Nikonov +10 more
doaj +2 more sources
THE SYNTHESIS OF SOME ISOQUINOLINES
A number of new isoquinolines substituted in the benzene nucleus have been prepared. The substituents include hydrazine-, chloro-, nitro-, and some combinations of these.
R H F, MANSKE, M, KULKA
openaire +3 more sources
A variety of thieno[3,2-f]isoquinolines were prepared by combination of Pd catalysed cross-coupling reactions with Brønsted acid mediated cycloisomerisations. The reactions tolerate various functional groups and proceed with high selectivity. In addition,
Maria Ines Mangione +11 more
core +1 more source
Nitrogen atom insertion into indenes to access isoquinolines [PDF]
We report a convenient protocol for a nitrogen atom insertion into indenes to afford isoquinolines. The reaction uses a combination of commercially available (diacetoxy¬iodo)benzene (PIDA) and ammonium carbamate to furnish a wide range of isoquinolines ...
Ori, Green +5 more
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Oxidation and hydrogenation of benzo[g]isoquinolines
The oxidation of methyl-substituted (in the pyridine and benzene rings) benzo[g]isoquinolines to substituted 2-azaanthraquinones was realized. It was established that the pyridine ring is partially reduced to give 1,2,3,4-tetrahydrobenzo[g]isoquinolines ...
Kirillova L.M. +3 more
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A Concise Total Synthesis of the Fungal Isoquinoline Alkaloid TMC-120B
Recent reports of antiepileptic activity of the fungal alkaloid TMC-120B have renewed the interest in this natural product. Previous total syntheses of TMC-120B comprise many steps and have low overall yields (11–17 steps, 1.5–2.9% yield).
Ahmad K. Haidar +6 more
doaj +1 more source
Nitration of Pyrrolo[2,1‑a]isoquinolines
We have successfully modified a series of pyrrolo[2,1-a]isoquinolines via direct nitration under mild reaction conditions. Easily accessible nitrates including CAN, Cu(NO3)2·H2O, and Fe(NO3)3·9H2O all can serve as effective nitrating reagents for ...
Xiao-Hui Chen (543865) +6 more
core +1 more source
Recent Advances in the Synthesis of Isoquinoline-Fused Benzimidazoles
This review includes recent developments in the synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines with particular attention given to categorizing protocols based on the structural features of the ring architecture and crystallographically characterized ...
Dylan J. Twardy +3 more
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Silver-Mediated Electrosynthesis of Substituted Isoquinolines via Cyclization of 2‑Ethynylbenzaldehydes [PDF]
Eliakin S. de Borba +7 more
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Studies concerning bridged isoquinolines and related compounds
This report describes studies concerning bridged isoquinolines and related compounds, Four aspects have been studied, Firstly, Diels-Alder reactions between heterarynes and different dienes have been carried out to provide 5,8-bridged isoquinolines.
Angela S. Mallard (7166759)
core +3 more sources

