Results 51 to 60 of about 9,595 (219)
Beilstein Journal of Organic Chemistry, 2020 Two kinds of [3 + 2] cycloaddition intermediates generated from the three-component reactions of 2-bromobenzaldehydes and maleimides with amino esters or amino acids were used for a one-pot N-allylation and intramolecular Heck reactions to form ...
Xiaoming Ma +6 more
doaj +1 more source
Benzo[de]naphtho[1,8-gh]quinolines: synthesis, photophysical studies and nitro explosives detection
Chimica Techno Acta, 2021 A rational synthetic approach to substituted naphtho[1,8-gh]quinolines using intramolecular cyclization in the presence of potassium in the series of (naphthalen-1-yl)isoquinolines is described. The photophysical properties of the obtained compounds were
Igor L. Nikonov +8 more
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Animal Research and One Health, EarlyView.Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian +8 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2014 An efficient one-pot tandem cyclization/[3 + 2] cycloaddition reaction of N’-(2-alkynylbenzylidene)hydrazides with ethyl 4,4,4-trifluorobut-2-ynoate under silver triflate-catalyzed or electrophile-mediated conditions is described.
Xiaoli Zhou +5 more
doaj +1 more source
Cobalt-Catalyzed ortho-C−H functionalization/alkyne annulation of benzylamine derivatives: Access to dihydroisoquinolines [PDF]
, 2017 A practical picolinamide-directed C−H functionalization/alkyne annulation of benzylamine derivatives enabling access to the previously elusive 1,4-dihydroisoquinoline skeleton was developed using molecular O2as the sole oxidant and Co(OAc)2as precatalyst.
Carretero, Juan C. +3 more
core +2 more sources
European Journal of Organic Chemistry, EarlyView.Resin‐supported tripeptide achieved the dynamic kinetic resolution in the catalytic aldol reaction of formylated heterobiaryl N‐oxides with high efficiency and enantioselectivity. The system features a broad substrate scope and a recyclable catalyst.
Jiaqi Tian +3 more
wiley +1 more source
Isoquinoline Alkaloids from the Leaves of
Natural Product Communications, 2007 This study was aimed at investigating the alkaloids present in the leaves of Dehaasia hainanensis. Thirteen isoquinolines were isolated and characterized.
Chien-Kuang Chen +3 more
doaj +1 more source
The Cyclisation of l-Aryl-2-Benzamidoalkan-l-Ols to 4,5-DihydroOxazoles or Isoquinolines [PDF]
, 1990 The cyclisation of several N-benzoyl derivatives of 2-amino-l-phenylpropan-l-ol w~e carried out employing the Pictet-Cams modification ofthe BischlerNapieralski reaction. The formation of4, 5-dihydro-oxazoles orisoquinolines depends on the substituents
Md. Sharif, Atan, O. Fitton, Alan
core
Rapid Discovery of Pyrido[3,4- d ]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach [PDF]
, 2016 Monopolar spindle 1 (MPS1) plays a central role in the transition of cells from metaphase to anaphase and is one of the main components of the spindle assembly checkpoint.
Baker, R +25 more
core +2 more sources