Results 71 to 80 of about 9,595 (219)

Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro‐Organic Synthesis

The Chemical Record, EarlyView.
Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe, Johannes Schneider, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Occurrence and Washout of Health‐Hazardous Chemicals in Children's Clothing

Contact Dermatitis, EarlyView.
A survey of 60 children's garments from the Swedish market showed a varying, often highly complex chemical content. The highest levels were generally found in synthetic materials and the lowest in light‐coloured cotton. Further, the washout effect by laundry and sweat migration of textile chemicals was investigated.
Awat Dostberg, Tim Åström, Ioannis Sadiktsis, Conny Östman, Ulrika Nilsson   +4 more
wiley   +1 more source

2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19 [PDF]

, 2016
We demonstrate a designed scaffold-hop approach to the discovery of 2,8-disubstituted-1,6-naphthyridine- and 4,6-disubstituted-isoquinoline-based dual CDK8/19 ligands.
Blagg, Julian, Burke, Rosemary, Busch, Michael, Clarke, Paul A., Czodrowski, Paul, Eccles, Suzanne A., Esdar, Christina, Honey, Mark A., Mallinger, Aurélie, Musil, Djordje, Poeschke, Oliver, Raynaud, Florence I., Rink, Christian, Rohdich, Felix, Schiemann, Kai, Schneider, Richard, Schwartz, Daniel, Sejberg, Jimmy, Stubbs, Mark, Urbahns, Klaus, Wienke, Dirk, Workman, Paul   +21 more
core   +5 more sources

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

1,3-Dien-5-ynes: Versatile Building Blocks for the Synthesis of Carbo- and Heterocycles [PDF]

, 2016
1,3-Dien-5-ynes have been extensively used as starting materials for the synthesis of a wide number of different carbo- and heterocycles. The aim of this review is to give an overview of their utility in organic synthesis, highlighting the variety of ...
Aguilar, Enrique, Fernández Rodríguez, Manuel A., García García, Patricia, Sanz Díez, Roberto   +3 more
core   +1 more source

Dopaminergic isoquinolines with hexahydrocyclopenta[ ij ]-isoquinolines as D 2 -like selective ligands

European Journal of Medicinal Chemistry, 2016
Dopamine receptors (DR) ligands are potential drug candidates for treating neurological disorders including schizophrenia or Parkinson's disease. Three series of isoquinolines: (E)-1-styryl-1,2,3,4-tetrahydroisoquinolines (series 1), 7-phenyl-1,2,3,7,8,8a-hexahydrocyclopenta[ij]-IQs (HCPIQs) (series 2) and (E)-1-(prop-1-en-1-yl)-1,2,3,4 ...
Párraga, Javier, Andujar, Sebastian Antonio, Rojas, Sebastian, Gutierrez, Lucas Joel, El Aouad, Noureddine, Sanz, M. Jesús, Enriz, Ricardo Daniel, Cabedo, Nuria, Cortes, Diego   +8 more
openaire   +5 more sources

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, EarlyView.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire, Wesley J. Olivier, Debabrata Maiti, Alex C. Bissember   +3 more
wiley   +2 more sources

Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010

Molecules, 2011
Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010.
Margareth de Fátima Formiga Melo Diniz, José Maria Barbosa Filho, Petrônio Filgueiras de Athayde-Filho, Marcelo Sobral da Silva, Josean Fechine Tavares, Augusto Lopes Souto   +5 more
doaj   +1 more source

Chiral Bronsted Acid-Catalyzed Enantioselective alpha-Amidoalkylation Reactions: A Joint Experimental and Predictive Study, [PDF]

, 2016
Enamides with a free NH group have been evaluated as nucleophiles in chiral Bronsted acid-catalyzed enantioselective alpha-amidoalkylation reactions of bicyclic hydroxylactams for the generation of quaternary stereocenters.
Aranzamendi Uruburu, Eider, Arrasate Gil, Sonia, González Díaz, Humberto, Lete Expósito, María Esther, Sotomayor Anduiza, María Nuria   +4 more
core   +3 more sources