Results 71 to 80 of about 7,156 (173)

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Synthesis of ([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)phosphonates and their benzo derivatives via 5-exo-dig cyclization

Beilstein Journal of Organic Chemistry, 2019
A series of novel 3-methylphosphonylated [1,2,4]triazolo[4,3-a]pyridines was accessed through a 5-exo-dig-type cyclization of chloroethynylphosphonates and commercially available N-unsubstituted 2-hydrazinylpyridines. In addition, 3-methylphosphonylated [
Aleksandr S. Krylov, Artem A. Petrosian, Julia L. Piterskaya, Nataly I. Svintsitskaya, Albina V. Dogadina   +4 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Electrochemical Skeletal Editing via Manganese‐Catalyzed Nitrogen Atom Insertion Scalable by Electroflow

ChemistryEurope
Molecular editing and atom insertion are powerful tools for the late‐stage construction of complex molecular architectures, especially in medicinal chemistry.
Simon L. Homölle, Tristan Bauch, Aboubakr Hamad, Bo‐Sheng Zhang, Lutz Ackermann   +4 more
doaj   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Constructing High‐Performance PVDF‐Based Piezoelectric Composites via Hydrogen Bond Anchoring Strategy for Flexible Sensing Applications

Transformative Chemistry, EarlyView.
This work proposes a full‐surface hydrogen bonding anchoring strategy to construct a high‐performance piezoelectric sensor for intelligent sensing. ABSTRACT Fluoropolymers are crucial for next‐generation lightweight, portable, and human–computer interactive devices.
Yuying Wu, Si Chen, Zijie Luo, Gang Zhou, Lei Zhu, Xinyuan Zhu, Youfu Wang, Xin Jin   +7 more
wiley   +1 more source

Aryl Radical Cyclizations of 1-(2‘-Bromobenzyl)isoquinolines with AIBN−Bu₃SnH:  Formation of Aporphines and Indolo[2,1-a]isoquinolines

, 2016
Radical cyclization of alkoxy-substituted 1-(2‘-bromobenzyl)-3,4-dihydroisoquinolines 1 with AIBN−Bu3SnH gave 6a,7-dehydroaporphines 2 preferentially.
Shiho Uchiito (2476501), Kazuhiko Orito (2358016), Rika Harada (3062520), Yoshitaka Satoh (1889563), Masao Tokuda (2358013), Takashi Tatsuzawa (3075573)   +5 more
core   +1 more source

Seasonal Dynamics of Community and Function of Gut Microbiome in Taihangshan Macaque (Macaca mulatta tcheliensis): Inferred From Metagenomic Data

Integrative Zoology, EarlyView.
A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou, Qi Shao, Chunbo Liu, Jundong Tian, Xiaowen Guan, Xi Zhang, Jiqi Lu   +6 more
wiley   +1 more source

Harnessing the reactivity of ortho-formyl-arylketones: base-promoted regiospecific synthesis of functionalized isoquinolines

, 2019
An efficient and base-mediated one-pot regiospecific synthesis of structurally diversified isoquinolines and benzo[h] isoquinolines from easily accessible ortho-formyl-arylketones and aryl/(het)arylmethanamines has been described.
Verma, S., Mishra, Pawan K, Verma, Shalini, Verma, A. K., Kumar, Manoj, Kumar, M., Verma, Akhilesh K, Kumar, Ankit, Kumar, A., Mishra, P. K.   +9 more
core   +1 more source

Insights Into the Origin and Local Adaptation Evolution of the Cultivated Sesame With Telomere‐to‐Telomere High‐Quality Genome

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sesame (Sesamum indicum L., 2n = 26) is one of the oldest oilseed crops and is often called the ‘queen of oilseeds’ due to its high content of unsaturated fatty acids and natural antioxidants. Despite its long history, the origin and global spread of cultivated sesame remain unresolved.
Weifei Yang, Hengchun Cao, Hui Guo, Hongmei Miao, Guiting Li, Yinghui Duan, Ming Ju, Qiuzhen Tian, Qin Ma, Pengjie Chang, Zhanyou Zhang, Cong Mu, Xiaoxu Feng, Libin Wei, Weixiu Hou, Andrew H. Paterson, Haiyang Zhang   +16 more
wiley   +1 more source