Results 171 to 180 of about 26,794 (255)

De Novo Design of Multivalent α/β‐Peptides Mimicking Transcription Factors Targeting the CBP KIX Domain

Chemistry – A European Journal, EarlyView.
A modular, de novo α/β‐peptide design strategy allows fine‐tuning of ligand properties, resulting in multivalent ligands that simultaneously target separate binding sites on the protein surface. ABSTRACT Protein‐protein interactions that regulate gene expression in the nucleus are increasingly recognized as potential therapeutic targets but present ...
Márk V. Tresztián, Vencel L. Petrovicz, Edit Wéber, Tamás A. Martinek, Zsófia Hegedüs   +4 more
wiley   +1 more source

Linker Symmetry Lowering as a Strategy to Tune Electronic Properties in Two‐Dimensional Conductive MOFs

Chemistry – A European Journal, EarlyView.
We present a two‐dimensional conductive metal‐organic framework (2D cMOF) constructed from an organic linker with lower symmetry than those commonly used in related systems. The resulting reduction in lattice symmetry lifts band degeneracies, reshapes the electronic structure, and opens a larger band gap.
Bowen Tan, Tianyang Chen, Mingyu Jeon, Julius J. Oppenheim, Mircea Dincă   +4 more
wiley   +1 more source

Rapid and visual detection of Tacheng tick virus 1 using loop-mediated isothermal amplification technique. [PDF]

Front Cell Infect Microbiol
Guo Q, Gui Z, Ren Y, Liu Z, Liu N, Li L, Wang Z, Yu J.   +7 more
europepmc   +1 more source

Nano MIPs (Molecularly Imprinted Polymers) Prepared From a “Frustrated” Gold Nanoparticle‐Based Pre‐Imprinting Matrix: Enhancing Binding Affinity and Selectivity

Chemistry – A European Journal, EarlyView.
A comparative study across ligand‐stabilized gold nanoparticles and surfactant micelles reveals that molecular imprinting strongly depends on the nanoplatform used for imprinting. “Frustrated” noncovalent interactions within the monolayer on gold nanoparticle surface can be exploited to improve both the binding affinity and selectivity for ...
Mansi Sharma, Dashaunette D. Wallace, Yan Zhao   +2 more
wiley   +1 more source

A universal kinetic framework for quantitative isothermal amplification governed by polymerase speed, amplicon size, and binding efficiency. [PDF]

Nucleic Acids Res
Tang L, Guo Z, Wu J, Li Y, Yang K.
europepmc   +1 more source

An Analytical Design Model of a Vacuum Pressure Swing Adsorption Process for Biogas Upgrading

Chemie Ingenieur Technik, EarlyView.
A steady‐state model was developed for a vacuum pressure swing adsorption (VPSA) process comprising adsorption, depressurization, and evacuation steps. The resulting analytical plant design model provides the optimal adsorber height required to achieve a target product purity with maximum bed utilization.
Thomas Welter, Jan Mackel, Niklas Döring, Hilario Vidal   +3 more
wiley   +1 more source

Impact of Trace Water on the Macroscopic Activity of Commercial Ammonia Cracking Catalysts Under Process‐Relevant Conditions

Chemie Ingenieur Technik, EarlyView.
This study evaluates how small water impurities—typical in ammonia cracking feedstock—affect catalyst performance at elevated pressures and temperatures. By decoupling permanent degradation from reversible inhibition, the findings highlight trace water as a significant factor for reliable catalyst screening and industrial ammonia cracking scale‐up ...
Bruno V. P. Lago, Sebastian Wodak, Marianne Ponceau, Axel Behrens, Jan‐Peter Bohn, Sebastian Rehfeldt, Harald Klein   +6 more
wiley   +1 more source

Loop-mediated isothermal amplification combined with a Pyrococcus furiosus argonaute system for the rapid detection of goose astrovirus. [PDF]

Poult Sci
Yang F, Liu Z, Ye J, Xie Q, Wu C, Jiang C, Wu H, Gu Q, Song D, Zhang F.   +9 more
europepmc   +1 more source

Comparative assessment of volume‐of‐fluid (VOF) multiphase solvers for viscoplastic flow over grooved patterned surfaces

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Accurately simulating multiphase flows at low capillary numbers remains challenging due to spurious currents and interface discretization errors. We present a systematic comparison of four volume‐of‐fluid (VOF) solvers within the OpenFOAM framework for pressure‐driven Poiseuille–Bingham flow over grooved surfaces: interFoam with classical ...
Amir Joulaei, Alice Villette, Seyed Mohammad Taghavi   +2 more
wiley   +1 more source

Comparative analysis of diagnostic efficacy of loop-mediated isothermal amplification (LAMP) and CBNAAT in children with suspected tubercular meningitis: a cross-sectional study. [PDF]

BMJ Paediatr Open
Jain S, Dayal R, Kamal R, Singh D, Yadav N, Nayak M, Khan A, Gupta S, Lawaniya S, Awasthi AK.   +9 more
europepmc   +1 more source