Results 11 to 20 of about 258,689 (296)

Anti-Cancer and Medicinal Potentials of Moringa Isothiocyanate

Molecules, 2021
Moringa oleifera (M. oleifera), which belongs to the Moringaceae family, is a common herb, rich in plant compounds. It has a variety of bioactive compounds that can act as antioxidants, antibiotics, anti-inflammatory and anti-cancer agents, etc., which ...
Yu-Yao Wu, Yan-Ming Xu, Andy T. Y. Lau
semanticscholar   +1 more source

Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells

Frontiers in Pharmacology, 2021
The latest research shows that current chemotherapeutics are ineffective because of the development of resistance in cervical cancer cells, and hence, their scope of use is limited.
Shoaib Shoaib, Saba Tufail, M. Sherwani, N. Yusuf, N. Islam   +4 more
semanticscholar   +1 more source

The phytopathogenic fungus Sclerotinia sclerotiorum detoxifies plant glucosinolate hydrolysis products via an isothiocyanate hydrolase

Nature Communications, 2020
Brassicales plants produce glucosinolates and myrosinases that generate toxic isothiocyanates conferring broad resistance against pathogens and herbivorous insects.
Jingyuan Chen, C. Ullah, M. Reichelt, F. Beran, Zhi-Ling Yang, J. Gershenzon, A. Hammerbacher, D. G. Vassão   +7 more
semanticscholar   +1 more source

Anti‐pruritic effect of isothiocyanates: Potential involvement of toll‐like receptor 3 signaling

Pharmacology Research & Perspectives, 2022
The innate immune system has an emerging role as a mediator of neuro‐immune communication and a therapeutic target for itch. Toll‐like receptor 3 (TLR3) plays an important role in itch, as shown in TLR3 knock‐out mice.
Masaki Moriyama, Mitsuhiro Konno, Kanako Serizawa, Natsumi Yuzawa, Yuki Majima, Ikuo Hayashi, Tomohiko Suzuki, Mie Kainoh   +7 more
doaj   +1 more source

Moringin, A Stable Isothiocyanate from Moringa oleifera, Activates the Somatosensory and Pain Receptor TRPA1 Channel In Vitro

Molecules, 2020
Moringa oleifera Lam. is a tropical plant widely used in traditional medicines and as a food supplement. It is characterized by the presence of glucosinolates and isothiocyanates; the stable isothiocyanate 4-[(α-l-rhamnosyloxy)benzyl]isothiocyanate ...
Gigliola Borgonovo, L. De Petrocellis, A. Schiano Moriello, S. Bertoli, A. Leone, A. Battezzati, S. Mazzini, A. Bassoli   +7 more
semanticscholar   +1 more source

Crystal structure of (diethyl ether-κO)[5,10,15,20-tetrakis(2-isothiocyanatophenyl)porphyrinato-κ4N]zinc diethyl ether solvate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The crystal structure of the title compound, [Zn(C48H24N8S4)(C4H10O)]·C4H10O, consists of discrete porphyrin complexes that are located on a twofold rotation axis.
Lisa Leben, Eike Schaub, Christian Näther, Rainer Herges   +3 more
doaj   +1 more source

New crystal packing arrangements in radical cation salts of BEDT-TTF with [Cr(NCS)6]3− and [Cr(NCS)5(NH3)]2− [PDF]

, 2015
BEDT-TTF forms three packing arrangement styles in its radical cation salts with [Cr(NCS)6]3− in two of which two trans-oriented isothiocyanate ligands penetrate the BEDT-TTF layers either at the point where a solvent (nitrobenzene) is incorporated in a ...
Akutsu, Allen, Andrew C. Brooks, Avarvari, Barbour, Bolm, Bérézovsky, Carlson, Coles, Coronado, Coronado, Day, Guionneau, Gómez-García, John D. Wallis, Kepert, Kepert, Kurmoo, Le Magueres, Lee Martin, Lequan, Macrae, Mallah, Martin, Martin, Martin, Martin, Martin, Martin, Martin, Mas-Torrent, Mori, Mori, Mori, Peppel, Peter Day, Pop, Prokhorova, Rikken, Riobé, Ross W. Harrington, Saito, Sheldrick, Singleton, Spek, Thétiot, Triki, Turner, Turner, Urayama, Wang, William Clegg   +51 more
core   +1 more source

Isothiocyanate from Broccoli, Sulforaphane, and Its Properties.

Journal of Medicinal Food, 2019
Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially in broccoli sprouts.
A. Vanduchová, P. Anzenbacher, E. Anzenbacherová   +2 more
semanticscholar   +1 more source

A Combined Approach of NMR and Mass Spectrometry Techniques Applied to the α-Cyclodextrin/Moringin Complex for a Novel Bioactive Formulation †

Molecules, 2018
Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin, is an uncommon member of the isothiocyanate class, and has been proven to possess a broad range of biological activities such as antitumor activity, protection ...
David Mathiron, Renato Iori, Serge Pilard, Thangavelu Soundara Rajan, David Landy, Emanuela Mazzon, Patrick Rollin, Florence Djedaïni-Pilard   +7 more
doaj   +1 more source

Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate

Molbank, 2017
This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source