Results 211 to 220 of about 266,552 (386)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

Editorial: Glucosinolate Metabolites: Bioavailability, Bioactivity and Clinical Variability

open access: yesFrontiers in Nutrition, 2021
Donato Angelino, Elizabeth H. Jeffery
doaj   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu   +9 more
wiley   +1 more source

2′-Chloro-1-hydroxy-2-naphthanilide-4'- isothiocyanate — a New Cestodicidal Agent [1 ] [PDF]

open access: hybrid, 1978
Harindra Singh   +4 more
openalex   +1 more source

Characterization of a Drosophila glutathione transferase involved in isothiocyanate detoxification.

open access: yesInsect Biochemistry and Molecular Biology, 2018
D. Gonzalez   +12 more
semanticscholar   +1 more source

Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome

open access: yesAdvanced Science, EarlyView.
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado   +10 more
wiley   +1 more source

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