Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas
Structure of the "hit‐compound" found and the proposed interaction with the active site of the TMPRSS2 protease, involving a reversible mechanism of action, are shown. The COVID‐19 pandemic highlighted the urgent need for effective antiviral treatments targeting SARS‐CoV‐2.
Marco Minneci +6 more
wiley +1 more source
Antiviral Activity of Allyl Isothiocyanate Against Infectious Viruses. [PDF]
Falcó I, Sánchez G.
europepmc +1 more source
An electrochemical immunosensor based on ZnO nanorods functionalized with gold nanoparticle‐conjugated anti‐receptor‐binding domain antibodies enables rapid, noninvasive, and selective detection of SARS‐CoV‐2 in saliva, providing a promising platform for point‐of‐care diagnostic applications.
Fabíola Lelis de Castro +15 more
wiley +1 more source
Synergistic Antibacterial Mechanism of Benzyl Isothiocyanate and Resveratrol Against <i>Staphylococcus aureus</i> Revealed by Transcriptomic Analysis and Their Application in Beef. [PDF]
Liu J +6 more
europepmc +1 more source
Abstract The International Harmonisation Protocol (IHP) for Reticulocyte Percentage (%Retic) in CLSI‐H44‐A2 is a microscopic procedure performed on a new‐methylene‐blue‐stained blood film (NMB‐IHP). However, IHP‐compliant Measurement Procedures (MPs) based on flow cytometry (FCM) are recommended for practical and accurately assigned reference values ...
Yutaka Nagai +9 more
wiley +1 more source
The Gut Microbiota Metabolite Urolithin B Mitigates Cholestatic Liver Injury in Mice via Modulating the Crosstalk Between PPARα, Nrf2, and NF-κB Signaling Pathways. [PDF]
Alrawili HM +3 more
europepmc +1 more source
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Correction: New diagnostic assays for differential diagnosis between the two distinct lineages of bovine influenza D viruses and human influenza C viruses. [PDF]
Okda FA +4 more
europepmc +1 more source

