Results 41 to 50 of about 257,349 (337)

Isothiocyanate From Moringa oleifera Seeds Inhibits the Growth and Migration of Renal Cancer Cells by Regulating the PTP1B-dependent Src/Ras/Raf/ERK Signaling Pathway

Frontiers in Cell and Developmental Biology, 2022
Moringa oleifera Lam. is a tropical and subtropical plant that has been used for centuries as both food and traditional medicine. 4-[(α-L-Rhamnosyloxy) benzyl] isothiocyanate (MIC-1) is an active substance in M.
Jing Xie, Jing Xie, Jing Xie, Ying-Yan Qian, Yang Yang, Lin-Jie Peng, Jia-Ying Mao, Ming-Rong Yang, Yang Tian, Yang Tian, Yang Tian, Jun Sheng   +11 more
doaj   +1 more source

Method of neutralizing the corrosive surface of amine-cured epoxy resins [PDF]

, 1982
The corrosive alkaline surface layer of an epoxy resin product formed by the curing of the epoxy with an aliphatic amine is eliminated by first applying a non-solvent to remove most or all of the free unreacted amine and then applying a layer of a ...
Lee, S. Y.
core   +1 more source

Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]

, 2018
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco, Artés Hernández, Francisco de Asís, Collado Marín, Elena, Martínez Hernández, Ginés Benito, Venzke Klug, Tâmmila   +4 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Phenethyl Isothiocyanate and Cisplatin Co-Encapsulated in a Liposomal Nanoparticle for Treatment of Non-Small Cell Lung Cancer

Molecules, 2019
Lung cancer is the leading cause of cancer-related death in the Unites States, and approximately 85% of all lung cancers are classified as non-small cell lung cancer (NSCLC), which is extremely difficult to treat and its survival rate is low.
Mengwei Sun, Yi Shi, Utkarsh J. Dang, Anthony J. Di Pasqua   +3 more
doaj   +1 more source

Sulforaphane reduces obesity by reversing leptin resistance

eLife, 2022
The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life.
Işın Çakır, Pauline Lining Pan, Colleen K Hadley, Abdulrahman El-Gamal, Amina Fadel, Dina Elsayegh, Omnia Mohamed, Nasser M Rizk, Masoud Ghamari-Langroudi   +8 more
doaj   +1 more source

Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature [PDF]

, 2019
CD33 is a myeloid-associated marker and belongs to the sialic acid-binding immunoglobulin (Ig)-like lectin (Siglec) family. Such types of receptors are highly expressed in acute myeloid leukemia, which could be used in its treatment.
Baisaeng, Nuttakorn, Boonla, Chanchai, Bäumler, Hans, Georgieva, Radostina, Kaewprayoon, Waraporn, Kloypan, Chiraphat, Smuda, Kathrin, Suwannasom, Nittiya   +7 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

One Pathway Is Not Enough: The Cabbage Stem Flea Beetle Psylliodes chrysocephala Uses Multiple Strategies to Overcome the Glucosinolate-Myrosinase Defense in Its Host Plants

Frontiers in Plant Science, 2018
The cabbage stem flea beetle (Psylliodes chrysocephala) is a key pest of oilseed rape in Europe, and is specialized to feed on Brassicaceae plants armed with the glucosinolate-myrosinase defense system.
Franziska Beran, Theresa Sporer, Christian Paetz, Seung-Joon Ahn, Franziska Betzin, Grit Kunert, Anton Shekhov, Daniel G. Vassão, Stefan Bartram, Sybille Lorenz, Michael Reichelt   +10 more
doaj   +1 more source

Five-Coordinated Geometries from Molecular Structures to Solutions in Copper(II) Complexes Generated from Polydentate-N-Donor Ligands and Pseudohalides

Molecules, 2020
A novel series of mononuclear five-coordinated pseudohalido-Cu(II) complexes displaying distorted square bipyramidal: [Cu(L1)(NCS)2] (1), [Cu(L2)(NCS)2] (2) and [Cu(L3)(NCS)]ClO4 (5) as well as distorted trigonal bipyramidal: [Cu(isp3tren)(N3)]ClO4 (3), [
Franz A. Mautner, Roland C. Fischer, Ana Torvisco, Maher M. Henary, Febee R. Louka, Salah S. Massoud, Nahed M. H. Salem   +6 more
doaj   +1 more source