Results 41 to 50 of about 266,552 (386)
Gut Glucosinolate Metabolism and Isothiocyanate Production
Molecular Nutrition & Food Research, 2018 The glucosinolate‐myrosinase system in plants has been well studied over the years while relatively little research has been undertaken on the bacterial metabolism of glucosinolates.
A. Narbad, J. Rossiter
semanticscholar +1 more source
Micellar electrokinetic capillary chromatography—Synchronous monitoring of substrate and products in the myrosinase catalysed hydrolysis of glucosinolates [PDF]
, 2006 A micellar electrokinetic capillary chromatography (MECC) method has been developed for monitoring the myrosinase catalysed hydrolysis of 2-hydroxy substituted glucosinolates and the simultaneous formation of the corresponding degradation products ...
Bellostas, Natalia +2 more
core +1 more source
Nutrients, 2018 Glucoraphenin, a glucosinolate present in large quantities in radish is hydrolysed by myrosinase to form the isothiocyanate sulforaphene, which is believed to be responsible for its chemopreventive activity; however, the underlying mechanisms of action ...
Saie Brindha Kntayya +5 more
semanticscholar +1 more source
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation [PDF]
, 2012 Abnormal cellular accumulation of the dicarbonyl metabolite MG (methylglyoxal) occurs on exposure to high glucose concentrations, inflammation, cell aging and senescence.
Anwar, M. Maqsud +10 more
core +1 more source
PLoS ONE, 2017 Moringa oleifera Lam. is a tropical plant, used for centuries as food and traditional medicine. The aim of this study was to develop, validate and biochemically characterize an isothiocyanate-enriched moringa seed extract (MSE), and to compare the anti ...
A. Jaja-Chimedza +6 more
semanticscholar +1 more source
Anti-cancer activities of allyl isothiocyanate and its conjugated silicon quantum dots
Scientific Reports, 2018 Allyl isothiocyanate (AITC), a dietary phytochemical in some cruciferous vegetables, exhibits promising anticancer activities in many cancer models. However, previous data showed AITC to have a biphasic effect on cell viability, DNA damage and migration ...
P. Liu +6 more
semanticscholar +1 more source
The neuroprotective mechanisms and effects of sulforaphane
Brain Circulation, 2019 Sulforaphane (SFN) is a phytochemical found in cruciferous vegetables. It has been shown to have many protective effects against many diseases, including multiple types of cancer. SFN is a potent activator of the nuclear factor erythroid 2-related factor
Eric A Klomparens, Yuchuan Ding
doaj +1 more source
Genomic instability in human cancer: molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition [PDF]
, 2015 Genomic instability can initiate cancer, augment progression, and influence the overall prognosis of the affected patient. Genomic instability arises from many different pathways, such as telomere damage, centrosome amplification, epigenetic ...
Amedei, Amedeo +34 more
core +1 more source
Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1
Molecular Nutrition & Food Research, 2018 Cruciferous vegetables are rich sources of glucosinolates which are the biogenic precursor molecules of isothiocyanates (ITCs). The relationship between the consumption of cruciferous vegetables and chemoprotection has been widely documented in ...
Sharadha Dayalan Naidu +4 more
semanticscholar +1 more source
The antibacterial properties of isothiocyanates
Microbiology, 2015 Isothiocyanates (ITCs) are natural plant products generated by the enzymic hydrolysis of glucosinolates found in Brassicaceae vegetables. These natural sulfur compounds and their dithiocarbamate conjugates have been previously evaluated for their anti-cancerous properties.
Dufour, Virginie +2 more
openaire +4 more sources