Results 61 to 70 of about 190,436 (297)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

Friedel–Crafts-type reaction of pyrene with diethyl 1-(isothiocyanato)alkylphosphonates. Efficient synthesis of highly fluorescent diethyl 1-(pyrene-1-carboxamido)alkylphosphonates and 1-(pyrene-1-carboxamido)methylphosphonic acid

open access: yesBeilstein Journal of Organic Chemistry, 2015
Friedel–Crafts-type reaction of pyrene with diethyl 1-(isothiocyanato)alkylphosphonates promoted by trifluoromethanosulfonic acid afforded diethyl 1-(pyrene-1-carbothioamido)alkylphosphonates in 83–94% yield.
Anna Wrona-Piotrowicz   +6 more
doaj   +1 more source

Ethyl 5-(4-Bromophenyl)-4-methyl-1H-pyrrole-2-carboxylate

open access: yesMolbank, 2017
This note describes a sequence converting an oxime-substituted pyrrolidine into a trisubstituted pyrrole structure. The synthetic route is based on a double chlorination of the pyrrolidine substrate followed by the base induced formation of both an imine
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source

New Insights on the Role of Allyl Isothiocyanate in Controlling the Root Knot Nematode Meloidogyne hapla

open access: yesPlants, 2020
Biofumigation, although a well-known method, is still controversially debated as a management strategy for plant-parasitic nematodes (PPN). Its controlling effect is attributed to the production of isothiocyanates (ITCs) following the action of ...
Paul Dahlin, Johannes Hallmann
doaj   +1 more source

Fluorescent excitation and emission spectra of fluorescein isothiocyanate.

open access: yes, 2014
Fluorescent excitation and emission spectra of fluorescein isothiocyanate.
Anna J. Williams (549603)   +5 more
core   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

open access: yesAdvanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang   +8 more
wiley   +1 more source

Phenethyl isothiocyanate induces Ca2+ movement and cytotoxicity in PC3 human

open access: yes, 2011
The effect of phenethyl isothiocyanate (PEITC), a cruciferous vegetable-derived compound, on cytoplasmic free Ca2+ concentrations ([Ca2+]i) in prostate cells has not been explored.
Jan, Chung-Ren;Chen, Chung-Yi;Wang, Shu-Chi ;Kuo, Soong-Yu
core  

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Oxidimetric method of determination of allyl isothiocyanate in black mustard (Brassica nigra L.) with chloramine-T.

open access: yes, 1972
Allyl isothiocyanate is the factor responsible for the pungency and aroma of black mustard. A rapid analytical method has been developed for the determination of the isothiocyanate with chloramine-T. The isothiocyanate is quantitatively converted in acid
Raghavan, B.   +3 more
core   +1 more source

A Combined Approach of NMR and Mass Spectrometry Techniques Applied to the α-Cyclodextrin/Moringin Complex for a Novel Bioactive Formulation †

open access: yesMolecules, 2018
Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin, is an uncommon member of the isothiocyanate class, and has been proven to possess a broad range of biological activities such as antitumor activity, protection ...
David Mathiron   +7 more
doaj   +1 more source

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