Results 31 to 40 of about 23,169 (258)

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

Advanced Functional Materials, EarlyView.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik, Prannoy Seth, Maximilian Fusenig, Jens Friedrichs, Nicole Fertala, Passant Atallah, Uwe Freudenberg, Ayala Lampel, Carsten Werner   +8 more
wiley   +1 more source

¿Sobreestimamos las necesidades de líquidos? Complicaciones del uso de sueros isotónicos de mantenimiento en plantas de hospitalización pediátrica

Nefrología, 2022
Resumen: Introducción: La fluidoterapia intravenosa es un tratamiento ampliamente utilizado en pacientes pediátricos hospitalizados. El objetivo del estudio fue analizar las complicaciones asociadas al uso de sueros isotónicos de mantenimiento en ...
Jimena Pérez-Moreno, Ana Gutiérrez-Vélez, Laura Torres Soblechero, Felipe González Martínez, Blanca Toledo del Castillo, Eva Vierge Hernán, Rosa Rodríguez-Fernández   +6 more
doaj   +1 more source

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

Advanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood, Venkata S. Akshintala, Surya T. Evani, Rebecca A. Krimins, Yihan Wang, Keith Freel, Ahmed Ibrahim, Saowanee Ngamruengphong, Mouen Khashab, Stephen W. Hoag   +9 more
wiley   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source

Intraoperative isotonic balanced versus hypotonic crystalloids on postoperative sodium homeostasis in small children undergoing major neurosurgery: a randomized controlled trial

BMC Pediatrics
Background Whether intraoperative isotonic balanced maintenance fluid is associated with less variation in sodium homeostasis in small children undergoing major neurosurgery remains unknown.
Mao-Wei Xing, Yue Zhang, Hui-Ting Zhu, Chang Liu, Zhi-Yu Geng, Lin-Lin Song, Dong-Xin Wang   +6 more
doaj   +1 more source

Hypotonic and isotonic intravenous maintenance fluids in hospitalised paediatric patients: a randomised controlled trial

BMJ Paediatrics Open, 2019
Objective To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions.Design A randomised, controlled and double-blind clinical trial.Setting Department of Paediatrics in a tertiary general hospital (
Silvio Fabio Torres, Thomas Iolster, Eduardo Julio Schnitzler, Alejandro Javier Siaba Serrate, Nicolás A Sticco, Manuel Rocca Rivarola   +5 more
doaj   +1 more source

A method to prepare isotonic dextran–salt solutions [PDF]

Cytometry Part A, 2010
AbstractTo increase, in rheological studies of red cells, the viscosity of suspending media, high‐molecular‐weight polymers, e.g., dextrans, are added to electrolyte solutions. However, dextrans at typical concentrations (e.g., 15% w/w) contribute an appreciable portion to the osmotic pressure of the suspending medium.
openaire   +2 more sources

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

EARLY ENTERAL INFUSSIONS IN COMPLEX TREATMENT OF SEVERE COMBINED CHEST TRAUMA

Вестник хирургии имени И.И. Грекова, 2018
On the basis of study and treatment of 98 victims it was stated that the absorption of isotonic glucose electrolytes solutions in the small intestine was saved even increased in case of large hemorrhage in severe polytrauma with chest, abdominal injury ...
A. N. Tulupov, V. M. Luft, G. I. Sinenchenko, A. V. Lapitskiy, S. Sh. Taniya   +4 more
doaj   +1 more source