Results 31 to 40 of about 2,779,234 (237)

Hypertonic Activity of Injection Solutions Can Cause Post-injection Complications (Review)

Разработка и регистрация лекарственных средств, 2023
Introduction. A review of the scientific literature showed that the current standards for assessing the quality of drugs does not include an assessment of the osmotic activity of drug solutions and their local irritant effect on tissues at the sites of ...
A. L. Urakov, N. A. Urakova, Z. V. Shubina, L. V. Lovtsova, A. V. Samorodov, K. G. Gurevich, A. P. Stolyarenko, V. I. Korunas, D. O. Lipatov, D. D. Muminov   +9 more
doaj   +1 more source

Balanced multi-electrolyte solution versus normal saline for fluid therapy in aneurysmal subarachnoid hemorrhage: an influence on fluid and electrolytes balance and outcome

Frontiers in Medicine
IntroductionIsotonic crystalloids are commonly used for maintaining fluid balance and cerebral perfusion pressure in critical care patients with aneurysmal subarachnoid hemorrhage (aSAH).
Yu-Qing Duan, Ying Tian, Shuya Wang, Shan-Shan Xu, Ming-Yue Miao, Ran Gao, Rui Su, Mengxue Hou, Yuqing Chen, Zimeng Xu, Linlin Zhang, Jian-Xin Zhou   +11 more
doaj   +1 more source

Sodium chloride 0.9% versus Lactated Ringer in the management of severely dehydrated patients with choleriform diarrhoea

Journal of Infection in Developing Countries, 2013
Introduction: Although experience within Peru suggests clinical and physiological benefits of treating dehydration caused by diarrhoea with Lactated Ringer’s solution (LR) over sodium chloride 0.9%, (NaCl) there is little documented scientific evidence ...
Javier Antonio Cieza, Juana Hinostroza, Julio Arturo Huapaya, Cristian Paul León   +3 more
doaj   +1 more source

Biomechanically Tunable Nano-Silica/P-HEMA Structural Hydrogels for Bone Scaffolding

Bioengineering, 2021
Innovative tissue engineering biomimetic hydrogels based on hydrophilic polymers have been investigated for their physical and mechanical properties. 5% to 25% by volume loading PHEMA-nanosilica glassy hybrid samples were equilibrated at 37 °C in aqueous
Raffaella Aversa, Relly Victoria Petrescu, Florian Ion T. Petrescu, Valeria Perrotta, Davide Apicella, Antonio Apicella   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Comparison of Mean Arterial Blood Pressure and Heart Rate Changes in Response to Three Different Randomized Isotonic Crystalloid Boluses in Hypotensive Anesthetized Dogs [PDF]

, 2022
SIMPLE SUMMARY: Anecdotal reports of a paradoxical exacerbation of hypotension in response to a bolus of a balanced isotonic crystalloid solution containing acetate buffers in dogs under general anesthesia was studied in a prospective clinical trial. The
Silverstein, Deborah C., Giacomo Gianotti, Kantyka, Marta, Gianotti, Giacomo, Deborah C. Silverstein, Marta Kantyka, Vézina-Audette, Raphaël, Silverstein, Deborah C, Raphaël Vézina-Audette   +8 more
core   +2 more sources

Detecting Anomalous Cell Behavior in Electrochemical Battery Testing Using Machine Learning

Advanced Engineering Materials, EarlyView.
Machine‐learning‐based screening enables automated identification of anomalous battery cells from complementary electrochemical tests. A curated battery database supports configuration‐aware comparison of rate‐capability and impedance data. Supervised classification of rate‐test data achieves 90% accuracy, while CNN‐VAE‐based impedance analysis reaches
Minu Rose, Sanxchep Sharma, Veit Königer, Vincent Nebel, Jonas Oehm, Christian Weisenberger, Laura Bies, Volker Knoblauch   +7 more
wiley   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source