Results 21 to 30 of about 92,950 (293)

Spatially resolved isotope labeling [PDF]

open access: yesNature Methods, 2019
Electron-energy-loss spectroscopy with a scanning transmission electron microscope enables spatially resolved imaging of isotope-labeled molecules.
openaire   +2 more sources

An origin identification model for labeling of shiitake (Lentinula edodes)

open access: yesnpj Science of Food, 2021
With the increasing globalization of the food trade across countries and continents, reliable identification of the geographical origin of products is critical. In this study, we describe the limitations of the current origin labeling system for non-soil-
Ill-Min Chung   +6 more
doaj   +1 more source

Synthesis of Stable Isotope Deuterium Labeled Levofloxacin-D3

open access: yesJournal of Isotopes, 2023
In order to improve the stable isotope utilization rate, a simple and inexpensive synthesis method was developed. The synthesis of levofloxacin is based on piperazine as the starting material, and the reaction with carbobenzoxy chloride (CBZ-Cl) to get ...
XU Zhong jie;ZHANG Li;SUN Wen;ZHANG Pengshuai;LEI Wen
doaj   +1 more source

Incomplete Wood-Ljungdahl pathway facilitates one-carbon metabolism in organohalide-respiring Dehalococcoides mccartyi. [PDF]

open access: yes, 2014
The acetyl-CoA "Wood-Ljungdahl" pathway couples the folate-mediated one-carbon (C1) metabolism to either CO2 reduction or acetate oxidation via acetyl-CoA.
Alvarez-Cohen, Lisa   +8 more
core   +1 more source

Limitations of In-Vitro Labeling of Endothelial Cells with Indium-111 Oxine

open access: yesCell Transplantation, 1995
Indium-111 oxine labeling is widely used as a marker of endothelial cell attachment to vascular prostheses. The long term effect of labeling human adult endothelial cells (HAECs) with this isotope has not been determined.
H.M.H. Carr   +5 more
doaj   +1 more source

Synthesis of Sulfachloropyridazine-Benzene Ring-13C6

open access: yesJournal of Isotopes, 2023
A synthesis route for stable isotope-labeled sulfamethoxazole-benzene ring-13C6 has been developed. In this strategy, 13C6-benzene was used as the source and starting material for stable isotope labeling and starting material to synthesize ...
MEI Shu;GUO Hui;CHEN Wulian
doaj   +1 more source

In Vivo Estimates of Liver Metabolic Flux Assessed by 13C-Propionate and 13C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions

open access: yesCell Reports, 2020
Summary: Isotope-based assessment of metabolic flux is achieved through a judicious balance of measurements and assumptions. Recent publications debate the validity of key assumptions used to model stable isotope labeling of liver metabolism in vivo ...
Clinton M. Hasenour   +2 more
doaj   +1 more source

Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex [PDF]

open access: yes, 2012
BACKGROUND: Mutations in the chromodomain helicase DNA binding protein 7 gene (CHD7) lead to CHARGE syndrome, an autosomal dominant multiple malformation disorder. Proteins involved in chromatin remodeling typically act in multiprotein complexes.
Batsukh, Tserendulam   +7 more
core   +3 more sources

Ultra-sensitive isotope probing to quantify activity and substrate assimilation in microbiomes

open access: yesMicrobiome, 2023
Background Stable isotope probing (SIP) approaches are a critical tool in microbiome research to determine associations between species and substrates, as well as the activity of species. The application of these approaches ranges from studying microbial
Manuel Kleiner   +10 more
doaj   +1 more source

Synthesis of isotopically labeled epothilones [PDF]

open access: yesJournal of Labelled Compounds and Radiopharmaceuticals, 2013
The epothilones, including epothilones B and D, are macrocyclic lactones, which have potent cytotoxicities and promote the polymerization of tubulin to mictotubules by binding to and stabilizing the tubulin polymer. They have a very similar mechanism of action to paclitaxel (Taxol®).
Thota, Ganesh   +4 more
openaire   +2 more sources

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