Results 81 to 90 of about 67,280 (303)
The molecular level understanding of proteins at oil‐water interfaces is deepened. Cruciferin assumes trimeric conformations at the interface, as in solution. Interfacial mobility is only marginally lower than in solution, indicating the chemical structure preserves a network.
Olaf Holderer+12 more
wiley +1 more source
Weak G-band stars on the H-R Diagram: Clues to the origin of Li anomaly [PDF]
Weak G-band (WGB) stars are a rare class of cool luminous stars that present a strong depletion in carbon, but also lithium abundance anomalies that have been little explored in the literature since the first discovery of these peculiar objects in the ...
A. Palacios+53 more
core +3 more sources
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu+10 more
wiley +1 more source
Ratio of natural isotopes of nitrogen. I. Primary results: soils of Dombes [Translation from: Revue d'Ecologie et de Biologie du Sol 14, 279-287, 1977] [PDF]
Utilization of the heavy isotope of nitrogen as a tracer has found numerous applications in soil biology. It allows better definition of different stages of the nitrogen cycle, in particular the immobilization-mineralization cycle.
Chalamet, A.+2 more
core
Partial (13)C isotopic enrichment of nucleoside monophosphates: useful reporters for NMR structural studies [PDF]
Analysis of the (13)C isotopic labeling patterns of nucleoside monophosphates (NMPs) extracted from Escherichia coli grown in a mixture of C-1 and C-2 glucose is presented. By comparing our results to previous observations on amino acids grown in similar
Kishore, Anita I.+2 more
core +2 more sources
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source
The capillary fringe is a subsurface terrestrial-aquatic interface that can be a significant hotspot for biogeochemical cycling of terrestrially derived organic matter and nutrients.
Nicholas J. Bouskill+8 more
doaj +1 more source
Relationship of body mass index to percent body fat determined by deuterium isotopic dilution and impedancemetry among Tunisian schoolchildren. [PDF]
Houda BJ+7 more
europepmc +1 more source