Results 51 to 60 of about 33,366 (300)

Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. [PDF]

, 2018
13-cis-retinoic acid (isotretinoin, INN) is an oral pharmaceutical drug used for the treatment of skin acne, and is also a known teratogen. In this study, the molecular mechanisms underlying INN-induced developmental toxicity during early cardiac ...
Geller, Benjamin S, Gruber, Joshua J, Jiang, Chao, Liu, Qing, Snyder, Michael P, Van Bortle, Kevin, Wu, Joseph C, Zhang, Joe Z, Zhang, Yue, Zhao, Ming-Tao   +9 more
core   +3 more sources

Systemic isotretinoin in the management of acne – a patient questionnaire survey

South African Family Practice, 2009
Background: The primary aim was to investigate the appropriateness (as outlined in the South African Acne Treatment Guideline 1) for the prescription of systemic isotretinoin in the management and counselling of acne in the Nelson Mandela Bay Metropole.
Solé Burger, Ilse Truter, Suzette M. Blignault, Danie J.L. Venter   +3 more
doaj   +1 more source

Efficacy and safety of isotretinoin in comparison to methotrexate in the patients suffering from moderate-to-severe plaque psoriasis: A prospective cohort study

Asian Journal of Medical Sciences, 2022
Background: Psoriasis is a common dermatological disorder with both inflammatory and genetic etiology. In India, the incidence of psoriasis is on the verge of rise.
Suhrita Paul , Abhijit Das , Chitrita Ghosh   +2 more
doaj   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

Side Effects of Treating Acne Vulgaris With Isotretinoin: A Systematic Review

Cureus
The treatment of acne vulgaris poses a significant challenge due to its chronic nature and potential influence on patients’ quality of life. Isotretinoin, a systemic retinoid, has emerged as one of the most efficient treatment options for chronic, severe
Ishika Rajput, V. Anjankar
semanticscholar   +1 more source

Analyzing the Efficacy of Isotretinoin in Treating Dissecting Cellulitis: A Literature Review and Meta-Analysis

Drugs in R&D, 2021
Background and Objective Dissecting cellulitis of the scalp is a primary scarring alopecia. Isotretinoin is commonly referenced in the literature as a treatment for dissecting cellulitis.
William Guo, Chencan Zhu, Gregg A. Stevens, D. Silverstein   +3 more
semanticscholar   +1 more source

Isotretinoin-Induced Hematuria in Acne Patients: Frequency, Risk Factors, and Management Recommendations from a Single-Center Study

Dermatology Practical & Conceptual
Introduction: Isotretinoin-induced hematuria is very rare; it has been reported in one study and individual case reports but never proven statistically.
Igor Kapetanovic, Jelena Nojer, Ivan Soldatovic, Dubravka Zivanovic, Natasa Maksimovic, Milos Nikolic, Snezana Minic   +6 more
doaj   +1 more source

Isotretinoin and Psychiatric Effects [PDF]

European Medical Journal Dermatology, 2014
Isotretinoin is a vitamin A derivative that has been commonly used by dermatologists for the treatment of acne. Isotretinoin has many dose-related side-effects, which have caused many debates lately, especially related to psychiatric and ...
Zennure Takci, AyseSerap Karadag, Hatice Burakgazi Yilmaz   +2 more
doaj  

Prevention of Isotretinoin-Induced Oxidative Stress and Hepatotoxicity [PDF]

MATEC Web of Conferences
Isotretinoin, also known as 13-cis-retinoic acid, is one of the most recognized treatments for the skin disease acne vulgaris, which is largely attributed to its high rates of success and overall effectiveness.
Xinyue Xu Catherine
doaj   +1 more source

Compliance with Pregnancy Prevention Recommendations for Isotretinoin Following the Amendment of the European Union Pregnancy Prevention Program: A Repeat Study in Estonia

Drugs - Real World Outcomes, 2023
Background Isotretinoin, indicated for severe acne, is a potent teratogen and therefore contraindicated in pregnancy. Thus, the pregnancy prevention program (PPP) for isotretinoin has been introduced.
Maaja Ivask, Katrin Kurvits, Maia Uusküla, Anne Juppo, Ott Laius, Mia Siven   +5 more
doaj   +1 more source