Results 91 to 100 of about 49,108 (308)

Localization of the selected peptides within the constant region of different antibody isotypes.

, 2013
Localization of the selected peptides within the constant region of different antibody isotypes.
Pier Paolo Zanello (328939), Alberto Spisni (328945), Serena Galati (328941), Elena Gabrielli (290619), Thelma A. Pertinhez (328944), Tiziana D'Adda (328940), Denise C. Arruda (320174), Stefania Conti (92354), Walter Magliani (92353), Eva Pericolini (290617), Marcia R. Pinto (328943), Luiz R. Travassos (92355), Anna Vecchiarelli (290625), Silvia Arancia (328942), Flavia De Bernardis (264590), Luciano Polonelli (92344), Tecla Ciociola (309997)   +16 more
core   +1 more source

isotype

Citation: 'isotype' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13347 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Kinetic constants and isotypes of mAbs binding to BoNT/B-Hc.

, 2012
Kinetic constants and isotypes of mAbs binding to BoNT/B-Hc.
Xin Shi (139139), Dapeng Zhang (89211), Huajing Wang (139132), Xiaoyan Mao (139134), Guanghui Ji (139137), Yajun Guo (72080), Changchun Chen (139128), Tiancheng Zhang (139135), Tian Xia (139140), Weijia Lu (139142), Jianxin Dai (139144), Shuhui Wang (139130)   +11 more
core   +1 more source

The potential to improve Lyme disease diagnostics through quantification of immunoglobulin class switching patterns

Journal of Clinical Microbiology
N. Nair, A. Marques , E. J. Horn, G. Brown et al., J Clin Microbiol 63:e0034725, 2025, https://doi.org/10.1128/jcm.00347-25 present data to demonstrate that infection by Borrelia burgdorferi, the primary causative agent of Lyme disease in the USA, leads ...
Anna M. Schotthoefer
doaj   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Distinct functional roles of β-tubulin isotypes in microtubule arrays of Tetrahymena thermophila, a model single-celled organism.

PLoS ONE, 2012
BackgroundThe multi-tubulin hypothesis proposes that each tubulin isotype performs a unique role, or subset of roles, in the universe of microtubule function(s).
Sandra Pucciarelli, Patrizia Ballarini, Daniela Sparvoli, Sabrina Barchetta, Ting Yu, H William Detrich, Cristina Miceli   +6 more
doaj   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Different genomic organization and expression of immunoglobulin light-chain isotypes in the rainbow trout

, 2000
cDNA studies have distinguished two isotypes of the rainbow trout (Oncorhynchus mykiss) immunoglobulin (Ig) light chain (designated L1 and L2). This study characterized genomic clones of these isotypes.
Partula, S, Timmusk, S,, Pilstrom, L
core  

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source