Results 61 to 70 of about 49,108 (308)

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Levels of antibody isotypes against MtM and Acr in study subjects.

, 2020
Levels of antibody isotypes against MtM and Acr in study subjects.
Amita Aggarwal (5401406), Ramnath Misra (1555531), Shashi Kant Kumar (4632523), Alok Nath (5782718), Sudhir Sinha (635376), Suvrat Arya (5782715), Prerna Kapoor (5782721)   +6 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

RawData＿The redundancy and diversity between two novel PKC isotypes that regulate learning in C. elegans.

, 2022
Raw data used in 'The redundancy and diversity between two novel PKC isotypes that regulate learning in C. elegans.
Yuichi Iino (8597784), Shingo Hiroki (11915438)   +1 more
core   +1 more source

Tubulin: Structure, Functions and Roles in Disease

Cells, 2019
Highly conserved α- and β-tubulin heterodimers assemble into dynamic microtubules and perform multiple important cellular functions such as structural support, pathway for transport and force generation in cell division.
Pavla Binarová, Jack Tuszynski
doaj   +1 more source

Salivary anti-nuclear antibody (ANA) mirrors serum ANA in systemic lupus erythematosus

Arthritis Research & Therapy, 2022
Objectives To assay salivary anti-nuclear antibody (ANA) and its isotypes in patients with systemic lupus erythematosus (SLE) and to investigate relevant clinical associations.
Ting Zhang, Yong Du, Qingqing Wu, Hao Li, Thao Nguyen, Gabriel Gidley, Valeria Duran, Daniel Goldman, Michelle Petri, Chandra Mohan   +9 more
doaj   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Analysis of antibody isotypes.

, 2016
Anti-Pvs48/45 sera showing positive reactivity to Pfs48/45 in ELISA and Western blotting (4 out of 5 from CFA group and 2 out of 5 from Montanide ISA-51 group) were individually tested to compare immunoglobulin isotypes. ELISA plates coated with Pvs48/45
Yi Cao (229829), Geetha P. Bansal (3149496), Kristen Merino (3149499), Nirbhay Kumar (113311)   +3 more
core   +1 more source

Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria

Malaria Journal, 2009
Background Plasmodium falciparum malaria is a complex disease in which genetic and environmental factors influence susceptibility. IgG isotypes are in part genetically controlled, and GM/KM allotypes are believed to be involved in this control.
Theander Thor G, Troye-Blomberg Marita, Arnot David, Iriemenam Nnaemeka C, Nasr Amre, Giha Hayder A, Berzins Klavs, ElGhazali Gehad, Pandey Janardan P   +8 more
doaj   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source