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The isoxazole alkaloids

2001
Publisher Summary Natural products based on the isoxazole (1,2-oxazole) skeleton constitute a small, heterogeneous group of natural products encompassing at present more than 90 structures. This group has not traditionally been classified as a special alkaloid group and has never been reviewed as a group previously.
L, Rahbaek, C, Christophersen
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Isoxazoles I: Protonation of Isoxazole Derivatives in Aqueous Sulfuric Acid

Journal of Pharmaceutical Sciences, 1973
The protonation of 3-amino-5-methylisoxazole, 5-amino-3,4-dimethylisoxazole, sulfamethoxazole (N-sulfanilamido-5-methyl-3-isoxazole), and sulfisoxazole (N-sulfanilamido-3,4-dimethyl-5-isoxazole) in aqueous sulfuric acid was studied. The pKSH+ and log SH+/S or log SH2+2/SH+ values were determined by UV spectrophotometry.
R H, Manzo, M M, De Bertorello
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Isoxazoles

2008
Isoxazoles, benzisoxazoles, isoxazolines, and isoxazolidines are classes of heterocyclic compounds having a remarkable number of applications and are very versatile building blocks in organic synthesis. The major developments on the chemistry of these heterocycles reported in the literature from 1996 to 2006 are reviewed.
GIOMI, DONATELLA   +2 more
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An Intercalating Isoxazole

Acta Crystallographica Section C Crystal Structure Communications, 1996
The title compound, ethyl 3-(9-anthryl)-5-methyl-4-isoxazolecarboxylate, C 21 H 17 NO 3 , possesses two planar ring systems that lie at 80° from coplanarity. The bond linking the two ring systems is 1.489 (3) A, indicating only partial conjugation between the two ring systems.
M. D. Mosher, N. R. Natale, A. Vij
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Isoxazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Isoxazole

Isoxazole is a versatile five-membered heterocyclic compound that has attracted significant attention due to its diverse medicinal chemistry and material science applications. This chapter provides a comprehensive overview of synthetic methodologies for preparing isoxazole derivatives, including traditional approaches such as cyclization reactions and ...
Popat Mohite, Savita Tauro, Aarati Pawar
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Studies in isoxazole chemistry. IV. Isoxazoles via isoxazolines

Canadian Journal of Chemistry, 1970
4- or 5-Chloro- or cyanoisoxazoles, 5-chloromethylisoxazoles, and 5-methylisoxazoles were made by the 1,3-dipolar cycloaddition of nitrile oxides to α-halogeno- or α-alkoxyolefins. In the case of cis- and trans-1,2-dichloroethylene, (5a and b) the intermediate cis- and trans-4,5-dichloroisoxalines (6a and b) were isolated.
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Isoxazole as a ligand

Inorganica Chimica Acta, 1975
Abstract A number of divalent 3d metal chloride and perchlorate complexes with isoxazole were obtained by interaction of salt and ligand in triethyl orthoformate-ethanol. Characterization of these complexes was based on spectral (ir--electronic), magnetic and conductance evidence.
N.M. Karayannis   +4 more
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Oxazolo[4,5-d]isoxazole Derivatives and 3,4-Disubstituted Isoxazoles from Isoxazol-5(4H)-ones

Synthetic Communications, 1993
Abstract Synthesis for oxazolo[4,5-d]isoxazole derivatives and 3,4-disubstituted isoxazoles from isoxazol-5(4H)-ones is reported.
E.M. Beccalli, A. Marchesini, T. Pilati
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4.03 - Isoxazoles

2022
Isoxazoles, isoxazolines and isoxazolidines are a class of heterocyclic compounds having a remarkable number of applications and are very versatile building blocks in organic synthesis. The developments concerning the synthesis of the above monocyclic systems reported in the literature from 2007 to 2019 are reviewed.
Cordero, Franca M.   +2 more
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