Results 171 to 180 of about 16,147 (226)

The Role of Five-Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview. [PDF]

ChemMedChem
Finamore C, Festa C, Barbato R, Fiorucci S, Zampella A, De Marino S.   +5 more
europepmc   +1 more source

Advances in isoxazole chemistry and their role in drug discovery. [PDF]

RSC Adv
Martis GJ, Gaonkar SL.
europepmc   +1 more source

5-(Thiophen-2-yl)isoxazoles as novel anti-breast cancer agents targeting ERα: synthesis, <i>in vitro</i> biological evaluation, <i>in silico</i> studies, and molecular dynamics simulation. [PDF]

RSC Med Chem
Pattanayak P, Nikhitha S, Halder D, Ghosh B, Chatterjee T.   +4 more
europepmc   +1 more source

Vanillin-tethered quinazolin-2,4-dione analogues through five- and/or six-membered nitrogen-containing heterocycles as antibacterial agents: synthesis, biological evaluation and molecular docking study. [PDF]

RSC Adv
Abdelmonsef AH, Elnaby SM, Mosallam AM, Rashdan HRM, Alsoghier HM, Raslan MA.   +5 more
europepmc   +1 more source

Synthesis of Isoxazole- and Oxazole-4-carboxylic Acids Derivatives by Controlled Isoxazole-Azirine-Isoxazole/Oxazole Isomerization

The Journal of Organic Chemistry, 2019
The first synthesis of isoxazole-4-carboxylic acid derivatives by domino isoxazole-isoxazole isomerization is reported. Fe(II)-catalyzed isomerization of 4-acyl-5-methoxy-/5-aminoisoxazoles (dioxane, 105 °C) leads to the formation of isoxazole-4-carboxylic esters and amides in good yields. 4-Formyl-5-methoxyisoxazoles give methyl oxazole-4-carboxylates
Anna V. Serebryannikova, Ekaterina E. Galenko, Mikhail S. Novikov, Alexander F. Khlebnikov   +3 more
core   +4 more sources

Isoxazole Hydrate

Canadian Journal of Chemistry, 1974
X-Ray, n.m.r., and dielectric studies show that the hydrate of isoxazole is a typical type II clathrate hydrate in structure, in reorientation rates of host and guest molecules, and in composition.
Gough, S.R., Garg, S.K., Ripmeester, J.A., Davidson, D.W.   +3 more
openaire   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Isoxazole anthelmintics

Journal of Medicinal Chemistry, 1977
A series of 3-halo-5-phenyl- and 3-phenyl-5-haloisoxazoles has demonstrated anthelmintic activity at doses ranging from 16 to 500 mg/kg orally against the rat roundworm, Nippostrongylus braziliensis. In the 5-phenyl series a halogen at the 3 position of the isoxazole ring was required for activity.
J B, Carr, H G, Durham, D K, Hass
openaire   +2 more sources

NH2OH–Mediated Lignin Conversion to Isoxazole and Nitrile

ACS Sustainable Chemistry and Engineering, 2018
Conversion of lignin to aromatic compounds via C-C/C-O bond cleavage has been an attractive but challenging subject in recent years. We herein report the first protocol that converts lignin models and preoxidized lignin to isoxazole and aromatic nitrile.
Hongji Li, Huifang Liu, Nengchao Luo
exaly   +2 more sources

Isoxazoles with antipicornavirus activity

Journal of Medicinal Chemistry, 1985
The synthesis and evaluation of a series of 3,5-disubstituted isoxazoles as antipicornavirus agents have led to the discovery of several compounds effective in vitro against rhinovirus type 2 and poliovirus type 2. Compound 32 was found more effective than 4',6-dichloroflavan against both viruses and was evaluated orally in mice infected ...
G D, Diana, M A, McKinlay, C J, Brisson, E S, Zalay, J V, Miralles, U J, Salvador   +5 more
openaire   +2 more sources