Results 111 to 120 of about 3,701 (179)

Efficient Synthesis, Structural Characterization, Antibacterial Assessment, ADME-Tox Analysis, Molecular Docking and Molecular Dynamics Simulations of New Functionalized Isoxazoles. [PDF]

Molecules
Arzine A, Hadni H, Boujdi K, Chebbac K, Barghady N, Rhazi Y, Chalkha M, Nakkabi A, Chkirate K, Mague JT, Kawsar SMA, Al Houari G, M Alanazi M, El Yazidi M.   +13 more
europepmc   +1 more source

Heterocycle-Tethered Aurones: Synthesis and Evaluation of α-Glucosidase Inhibition. [PDF]

Biomed Res Int
Kobzar OL, Popova AV, Bondarenko SP, Mrug GP, Vovk AI, Frasinyuk MS.   +5 more
europepmc   +1 more source

Iron-Catalyzed Nucleophilic Substitution Reactions: An Overview. [PDF]

ACS Omega
Ramamoorthy S, Ramasubramanian M, Sivaraj N, Dohi T, Singh FV.   +4 more
europepmc   +1 more source

Simple and versatile electrochemical synthesis of highly substituted 2,1-benzisoxazoles.

Org Biomol Chem
Lenhard MS, Winter J, Sandvoß A, Gálvez-Vázquez MJ, Schollmeyer D, Waldvogel SR.   +5 more
europepmc   +1 more source

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Isoxazole anthelmintics

Journal of Medicinal Chemistry, 1977
A series of 3-halo-5-phenyl- and 3-phenyl-5-haloisoxazoles has demonstrated anthelmintic activity at doses ranging from 16 to 500 mg/kg orally against the rat roundworm, Nippostrongylus braziliensis. In the 5-phenyl series a halogen at the 3 position of the isoxazole ring was required for activity.
J B, Carr, H G, Durham, D K, Hass
openaire   +2 more sources

Isoxazole Hydrate

Canadian Journal of Chemistry, 1974
X-Ray, n.m.r., and dielectric studies show that the hydrate of isoxazole is a typical type II clathrate hydrate in structure, in reorientation rates of host and guest molecules, and in composition.
Gough, S.R., Garg, S.K., Ripmeester, J.A., Davidson, D.W.   +3 more
openaire   +2 more sources

The isoxazole alkaloids

2001
Publisher Summary Natural products based on the isoxazole (1,2-oxazole) skeleton constitute a small, heterogeneous group of natural products encompassing at present more than 90 structures. This group has not traditionally been classified as a special alkaloid group and has never been reviewed as a group previously.
L, Rahbaek, C, Christophersen
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Isoxazoles with antipicornavirus activity

Journal of Medicinal Chemistry, 1985
The synthesis and evaluation of a series of 3,5-disubstituted isoxazoles as antipicornavirus agents have led to the discovery of several compounds effective in vitro against rhinovirus type 2 and poliovirus type 2. Compound 32 was found more effective than 4',6-dichloroflavan against both viruses and was evaluated orally in mice infected ...
G D, Diana, M A, McKinlay, C J, Brisson, E S, Zalay, J V, Miralles, U J, Salvador   +5 more
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Isoxazoles

2008
Isoxazoles, benzisoxazoles, isoxazolines, and isoxazolidines are classes of heterocyclic compounds having a remarkable number of applications and are very versatile building blocks in organic synthesis. The major developments on the chemistry of these heterocycles reported in the literature from 1996 to 2006 are reviewed.
GIOMI, DONATELLA, CORDERO, FRANCA MARIA, MACHETTI, FABRIZIO   +2 more
openaire   +3 more sources

Isoxazole

Isoxazole is a versatile five-membered heterocyclic compound that has attracted significant attention due to its diverse medicinal chemistry and material science applications. This chapter provides a comprehensive overview of synthetic methodologies for preparing isoxazole derivatives, including traditional approaches such as cyclization reactions and ...
Popat Mohite, Savita Tauro, Aarati Pawar
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