Results 91 to 100 of about 5,810 (212)

Calcium-mediated one-pot preparation of isoxazoles with deuterium incorporation

, 2018
In this work, a novel synthetic methodology for the one-pot preparation of isoxazoles directly from the reaction of calcium carbide with aldoximes is reported.
Konstantin S. Rodygin, Valentine P. Ananikov, Maria S. Ledovskaya   +2 more
core   +1 more source

An Intramolecular Wittig Approach toward Heteroarenes: Synthesis of Pyrazoles, Isoxazoles, and Chromenone-oximes

, 2019
α-Halohydrazones/ketoximes are transformed into trisubstituted pyrazoles/disubstituted isoxazoles by treatment with phosphine, acyl chloride, and a base.
Wenwei Lin, Praneeth Karanam, Tsai-Hui Lung (6714734), Athukuri Edukondalu, Athukuri Edukondalu (1393036), Chi-Yi Wu (6714737), Yi-Jung Lin (19416), Praneeth Karanam (6714743), Wenwei Lin (278782), Srinivasa Rao Koppolu, Tsai-Hui Lung, Chi-Yi Wu, Pankaj V. Khairnar (6714731), Yi-Jung Lin, Pankaj V. Khairnar, Srinivasa Rao Koppolu (6714740)   +15 more
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Direct ring fluorination of 3-substituted 5-(1,3-dioxane) acetal isoxazoles: application to the formal synthesis of a bioactive fluorinated isoxazole

Comptes Rendus. Chimie
The access to a novel variety of 4-fluorinated isoxazoles bearing an aryl or alkyl group at the C-3 position and an acetal fragment at the C-5 position has been achieved through a direct fluorination using N-fluorobenzenesulfonimide (NFSI) with yields up
Bacheley, Lucas, Guillamot, Gérard, Phansavath, Phannarath, Ratovelomanana-Vidal, Virginie   +3 more
doaj   +1 more source

Oxazolo[4,5-d]isoxazole derivatives and 3,4-disubstituted isoxazoles from isoxazol-5(4H)-ones

, 1993
Synthesis for oxazolo[4,5-d]isoxazole derivatives and 3,4-disubstituted isoxazoles from isoxazol-5(4H)-ones is ...
A. Marchesini, T. Pilati, E.M. Beccalli
core   +1 more source

Zinc-catalyzed reaction of isoxazoles with thioynol ethers involving an unprecedented 1,2-sulfur migration

, 2018
A novel zinc-catalyzed reaction of isoxazoles with thioynol ethers involving an unprecedented 1,2-sulfur migration has been developed.
Qing Sun, Xin-Qi Zhu, Bo Zhou, Pei-Xi Xie, Jin-Mei Zhou, Zhi-Xin Zhang, Xin Lu, Wen-Bo Shen, Long-Wu Ye   +8 more
core   +1 more source

Oxyboration with and without a Catalyst: Borylated Isoxazoles via B–O σ‑Bond Addition

, 2016
Herein we report an oxyboration reaction with activated substrates that employs B–O σ bond additions to C–C π bonds to form borylated isoxazoles, which are potential building blocks for drug discovery.
Joshua J. Hirner (1393651), Suzanne A. Blum (1312947), Kim N. Tu (1393648)   +2 more
core   +1 more source

Synthesis of the omega-brominated alpha-trifluoroacetylcycloalkanones and their isoxazole derivatives

Journal of the Brazilian Chemical Society, 2006
The reactions of a serie of the 2-trifluoroacetyl-1-methoxy-1-cycloalkenes (1a-1e) and 2-trifluoroacetylcycloalkanones (2a-2e) with molecular bromine to obtain omega-bromo-alpha-trifluoroacetylcycloalkanones (3a-3e, 4a) is reported. Was determined that 2-
Flores Alex F. C., Peres Rodrigo L., Piovesan Luciana A., Flores Darlene C., Bonacorso Helio G., Martins Marcos A. P.   +5 more
doaj  

Regioselective Synthesis of Polysubstituted Pyrazoles and Isoxazoles

, 2016
A regioselective synthesis has been developed for the preparation of unsymmetrical 1,3,5-triaryl-4-alkylpyrazolines and -pyrazoles by treatment of α-benzotriazolyl-α,β-unsaturated ketones with monosubstituted hydrazines followed by alkylation at the 4 ...
Peter J. Steel (1724674), Michael V. Voronkov (2338267), Alan R. Katritzky (455231), Mingyi Wang (91634), Suoming Zhang (1527271)   +4 more
core   +1 more source

Synthesis of new 3,5-substiuted isoxazole derivatives possessing potential anti-aggregative activity

Тонкие химические технологии, 2010
Two new compounds belonging to 3,5-substituted isoxazoles class were synthesized for the action mechanism investigation and the pharmacophore fragment determination of potential anti-aggregative compounds of this class.
O. V. Demina, A. V. Laptev, A. U. Lukin, N. E. Belikov, K. V. Zvezdin, M. A. Fomin, A. A. Khodonov, S. D. Varfolomeev, V. I. Shvets   +8 more
doaj  

Synthesis of some new isoxazolyldihydro[1,2,4]triazolo[1,5-b] isoxazoles and dihydroimidazo[4,5-b]indolylisoxazoles as possible biodynamic agents

, 2013
677-685Synthesis of new isoxazolyl[1,2,4]triazolo[1,5-b]isoxazoles and imidazo[4,5-b]indolyl isoxazoles have been achieved by interaction of isoxazole Schiff base with isoxazole amines and isatin ...
Rajanarendar, E, Ramakrishna, S, Venkateshwarlu, P   +2 more
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