Results 21 to 30 of about 84,859 (270)

Genetics of isozymes in grasspea [PDF]

open access: yesJournal of Heredity, 2000
We studied the inheritance and linkage of ACO-1, ACO-2, AAT-1, AAT-2, EST-3, EST-6, FDH, LAP-1, PGD-2, SKDH, and TPI-1 in four F2 populations of grasspea (Lathyrus sativus L.) using horizontal starch-gel electrophoresis. Mendelian inheritance was observed for all of the isozymes studied.
MA Chowdhury, A. E. Slinkard
openaire   +3 more sources

Potent Fluorescent Probe for Target‐Engagement Studies of Allosteric Pyruvate Kinase Modulators

open access: yesAngewandte Chemie, EarlyView.
LumiPK, a novel environment‐sensitive fluorescent tracer, enables direct monitoring of allosteric ligand engagement with pyruvate kinase fused with nanoluciferase (Nluc), focusing on the liver isoform (PKL). In NanoBRET, and fluorescence indicator displacement assays, LumiPK shows high affinity and validates known allosteric modulators of PKL.
Oscar Nilsson   +9 more
wiley   +2 more sources

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

open access: yes, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

Genetic variation within and among naturally regenerating populations of alder (Alnus glutinosa)

open access: yesActa Societatis Botanicorum Poloniae, 2011
To assess the inter- and intrapopulation genetic variation in the filial generation (F1) of alder (Alnus glutinosa (L.) Gaertn.), 11 naturally regenerated populations were analysed. Their parental populations (P), represent the whole Polish territory and
Leon Mejnartowicz
doaj   +1 more source

Low Degree Metabolites Explain Essential Reactions and Enhance Modularity in Biological Networks [PDF]

open access: yes, 2005
Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes and reactions that are essential for the organism.
Giri, Varun   +5 more
core   +4 more sources

INHERITANCE OF ISOZYMES: DESCRIPTION OF NEW LOCI IN ONIONS ISOZYMES [PDF]

open access: yesHortScience, 1993
Horizontal starch gel electrophoresis was used to study the mode of inheritance of isozyme phenotypes of four enzyme systems (ADH, 6-PGDH, PGM, and SKDH) in Allium cepa L. and A. fistulosum L. by monitoring segregations in backcross and F2 progeny. Segregation for most of the polymorphisms fit the expected Mendelian ratios as tested by the chi-square ...
Paul D. Mangum, Ellen B. Peffley
openaire   +2 more sources

Assessment of CYP‐Mediated Drug Interactions for Evocalcet, a New Calcimimetic Agent, Based on In Vitro Investigations and a Cocktail Study in Humans

open access: yesClinical and Translational Science, 2019
Evocalcet is a novel calcimimetic agent for the treatment of secondary hyperparathyroidism (SHPT). This study evaluated the effects of evocalcet on inhibition and induction of cytochrome P450 (CYP) isozymes.
Kazuya Narushima   +11 more
doaj   +1 more source

Insulin Action on Polyunsaturated Phosphatidic Acid Formation in Rat Brain: An “In Vitro” Model with Synaptic Endings from Cerebral Cortex and Hippocampus [PDF]

open access: yes, 2009
The highly efficient formation of phosphatidic acid from exogenous 1-stearoyl-2-arachidonoyl-sn-glycerol (SAG) in rat brain synaptic nerve endings (synaptosomes) from cerebral cortex and hippocampus is reported.
Giusto, Norma Maria   +2 more
core   +1 more source

Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. [PDF]

open access: yes, 2008
Following our previous research on anti-inflammatory drugs (NSAIDs), we report here the synthesis of chiral 1,5-diarylpyrroles derivatives that were characterized for their in vitro inhibitory effects toward cyclooxygenase (COX) isozymes.
ANZELLOTTI P.   +20 more
core   +1 more source

Population genetics of the pink snail Strombus gigas in the Yucatan Peninsula:Implications for its management and fishery

open access: yesCiencias Marinas, 2005
The genetic population structure of the pink snail Strombus gigas in the Yucatan Peninsula, Mexico, was determined by isozyme expression in polyacrylamide gels.
Jorge A Tello-Cetina   +2 more
doaj   +1 more source

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