Results 31 to 40 of about 1,719 (170)

INCOMPRESSIBLE SMOOTHED PARTICLE HYDRODYNAMICS (ISPH) MODELLING OF BREAKWATER OVERTOPPING [PDF]

Coastal Engineering Proceedings, 2014
This paper describes an investigation into using incompressible smoothed particle hydrodynamics (ISPH) to simulate the overtopping of a coastal structure such as a breakwater. The paper presents the ISPH formulation that employs the multiple boundary tangent method and the latest developments such as particle shifting that produce noise-free pressure ...
Rogers, Benedict D., Morellec, Maël, Stansby, Peter K., Skillen, Alex   +3 more
openaire   +2 more sources

ISPH modelling of transient natural convection

International Journal of Computational Fluid Dynamics, 2013
Transient and laminar natural convection in a square cavity has been investigated using smoothed particle hydrodynamics SPH technique as a discretisation tool on uniform Eulerian grids. Although SPH is a mesh-free Lagrangian method and always applied to discretise Lagrangian form of governing equations, in this study, Eulerian form of governing ...
Danis, M.E., Orhan, Mehmet, Ecder, A.
openaire   +5 more sources

Double diffusion in a nanofluid cavity with a wavy hot source subjected to a magnetic field using ISPH method

Alexandria Engineering Journal, 2021
A numerical study for the impacts of a magnetic field on double-diffusion within a nanofluid cavity with a wavy hot source is conducted using incompressible scheme of smoothed particle hydrodynamics (ISPH) method.
Abdelraheem Mahmoud Aly, Abdallah Aldosary, Ehab Mahmoud Mohamed   +2 more
doaj   +1 more source

Numerical investigation of free surface flood wave and solitary wave using incompressible SPH method [PDF]

Journal of Hydraulic Structures, 2016
Simulation of free surface flow and sudden wave profile are recognized as the most challenging problem in computational hydraulics. Several Eulerian/Lagrangian approaches and models can be implemented for simulating such phenomena in which the smoothed ...
Mohammad Zounemat-Kermani, Habibeh Sheybanifard   +1 more
doaj   +1 more source

Are Free Radicals Involved in IspH Catalysis? An EPR and Crystallographic Investigation [PDF]

Journal of the American Chemical Society, 2012
The [4Fe-4S] protein IspH in the methylerythritol phosphate isoprenoid biosynthesis pathway is an important anti-infective drug target, but its mechanism of action is still the subject of debate. Here, by using electron paramagnetic resonance (EPR) spectroscopy and (2)H, (17)O, and (57)Fe isotopic labeling, we have characterized and assigned two key ...
Weixue, Wang, Ke, Wang, Ingrid, Span, Johann, Jauch, Adelbert, Bacher, Michael, Groll, Eric, Oldfield   +6 more
openaire   +2 more sources

Insights into the Binding of Pyridines to the Iron–Sulfur Enzyme IspH

Journal of the American Chemical Society, 2014
(E)-1-Hydroxy-2-methylbut-2-enyl 4-diphosphate reductase (IspH) is a [Fe4S4] cluster-containing enzyme involved in isoprenoid biosynthesis in many bacteria as well as in malaria parasites and is an important drug target. Several inhibitors including amino and thiol substrate analogues, as well as acetylene and pyridine diphosphates, have been reported.
Span, Ingrid, Wang, Ke, Eisenreich, Wolfgang, Bacher, Adelbert, Zhang, Yong, Oldfield, Eric, Groll, Michael   +6 more
openaire   +2 more sources

3D ISPH erosion model for flow passing a vertical cylinder [PDF]

Journal of Fluids and Structures, 2018
In this paper a 3D incompressible Smoothed Particle Hydrodynamics (ISPH) erosion model\ud is proposed to simulate the scouring process behind a large vertical cylinder. The erosion\ud model is based on the turbidity water particle concept and the sediment motion is initiated\ud when the fluid bottom shear stress exceeds the critical value. The previous
Wang, D., Shao, S., Li, S., Shi, Y., Arikawa, T., Zhang, H.   +5 more
openaire   +2 more sources

Incompressible SPH (ISPH) with fast Poisson solver on a GPU

Computer Physics Communications, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Alex D. Chow, Benedict D. Rogers, Steven J. Lind, Peter Stansby   +3 more
openaire   +2 more sources

Discovery of acetylene hydratase activity of the iron–sulphur protein IspH [PDF]

Nature Communications, 2012
The final step of the methylerythritol phosphate isoprenoid biosynthesis pathway is catalysed by the iron-sulphur enzyme IspH, producing the universal precursors of terpenes: isopentenyl diphosphate and dimethylallyl diphosphate. Here we report an unforeseen reaction discovered during the investigation of the interaction of IspH with acetylene ...
Ingrid, Span, Ke, Wang, Weixue, Wang, Yonghui, Zhang, Adelbert, Bacher, Wolfgang, Eisenreich, Kai, Li, Charles, Schulz, Eric, Oldfield, Michael, Groll   +9 more
openaire   +2 more sources

Reconstruction and evaluation of the synthetic bacterial MEP pathway in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2012
Isoprenoids, which are a large group of natural and chemical compounds with a variety of applications as e.g. fragrances, pharmaceuticals and potential biofuels, are produced via two different metabolic pathways, the mevalonate (MVA) pathway and the 2-C ...
Siavash Partow, Verena Siewers, Laurent Daviet, Michel Schalk, Jens Nielsen   +4 more
doaj   +1 more source