Results 31 to 40 of about 2,497 (152)

HIV Care Coordination promotes care re-engagement and viral suppression among people who have been out of HIV medical care: an observational effectiveness study using a surveillance-based contemporaneous comparison group

AIDS Research and Therapy, 2021
Background Medical care re-engagement is critical to suppressing viral load and preventing HIV transmission, morbidity and mortality, yet few rigorous intervention studies address this outcome.
Mary K. Irvine, McKaylee M. Robertson, Denis Nash, Sarah G. Kulkarni, Sarah L. Braunstein, Bruce Levin   +5 more
doaj   +1 more source

Nonparametric Estimation of the Patient‐Weighted While‐Alive Estimand

Biometrical Journal, Volume 68, Issue 3, June 2026.
ABSTRACT In clinical trials with recurrent events, such as repeated hospitalizations terminating with death, it is important to consider the patient events overall history for a thorough assessment of treatment effects. The occurrence of fewer events due to early deaths can lead to misinterpretation, emphasizing the importance of a while‐alive strategy
Alessandra Ragni, Torben Martinussen, Thomas Scheike   +2 more
wiley   +1 more source

ISPH fusion proteins, ISPH inhibition, and bisphosphonate mechanism of action [PDF]

, 2018
In the first part of this work, IspH, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate reductase was studied. In most bacteria, apicomplexan parasites, and plants, the biosynthesis of the five carbon building blocks for terpenes is carried out by IspH. It
O'Dowd, Bing
core  

Seroincidence of SARS-CoV-2 infection prior to and during the rollout of vaccines in a community-based prospective cohort of U.S. adults

Scientific Reports
This study used repeat serologic testing to estimate infection rates and risk factors in two overlapping cohorts of SARS-CoV-2 N protein seronegative U.S. adults.
Denis Nash, Avantika Srivastava, Yanhan Shen, Kate Penrose, Sarah G. Kulkarni, Rebecca Zimba, William You, Amanda Berry, Chloe Mirzayi, Andrew Maroko, Angela M. Parcesepe, Christian Grov, McKaylee M. Robertson   +12 more
doaj   +1 more source

Numerical Analysis of Liquid Sloshing Using the Incompressible Smoothed Particle Hydrodynamics Method

Advances in Mechanical Engineering, 2015
A stabilized incompressible smoothed particle hydrodynamics (ISPH) method with the addition of a density invariant relaxation condition in the pressure calculations is applied to simulations of highly nonlinear liquid sloshing problems.
Abdelraheem M. Aly, Minh Tuan Nguyen, Sang-Wook Lee   +2 more
doaj   +1 more source

Hepatitis C virus risk among young people who inject drugs

Frontiers in Public Health, 2022
BackgroundInjection drug use (IDU) is the leading risk factor for hepatitis C virus (HCV) transmission in the U.S. While the general risk factors for HCV transmission are known, there is limited work on how these factors interact and impact young people ...
Pedro Mateu-Gelabert, Nasim S. Sabounchi, Honoria Guarino, Courtney Ciervo, Kellie Joseph, Benjamin J. Eckhardt, Chunki Fong, Shashi N. Kapadia, Terry T. K. Huang   +8 more
doaj   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1650-1661, June 2026.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Perceived Risk for Severe COVID-19 and Oral Antiviral Use Among Antiviral-Eligible US Adults

Infectious Diseases and Therapy
Introduction Oral antiviral medications are important tools for preventing severe COVID-19 outcomes. However, their uptake remains low for reasons that are not entirely understood.
Kate Penrose, Avantika Srivastava, Yanhan Shen, McKaylee M. Robertson, Sarah G. Kulkarni, Kristen E. Allen, Thomas M. Porter, Laura Puzniak, John M. McLaughlin, Denis Nash   +9 more
doaj   +1 more source

Dual convection of NEPCM inside an annulus between two circular cylinders mounted on rectangles

Alexandria Engineering Journal, 2023
This paper adopts the incompressible smoothed particle hydrodynamics (ISPH) method for simulating the dual diffusion of nano-encapsulated phase change material (NEPCM) in an annulus.
Zehba Raizah, Abdelraheem M. Aly
doaj   +1 more source

Vector bundles on bielliptic surfaces: Ulrich bundles and degree of irrationality

Mathematische Nachrichten, Volume 299, Issue 3, Page 514-528, March 2026.
Abstract This paper deals with two problems about vector bundles on bielliptic surfaces. The first is to give a classification of Ulrich bundles on such surfaces S$S$, which depends on the topological type of S$S$. In doing so, we study the weak Brill–Noether property for moduli spaces of sheaves with isotropic Mukai vector. Adapting an idea of Moretti
Edoardo Mason
wiley   +1 more source