Results 21 to 30 of about 1,719 (170)

Hepatitis C virus care cascade among people who inject drugs in Puerto Rico: Minimal HCV treatment and substantial barriers to HCV care

open access: yesDrug and Alcohol Dependence Reports, 2023
Background: People who inject drugs (PWID) in Puerto Rico are disproportionately affected by the hepatitis C virus (HCV) epidemic. However, there is a scarcity of data on the HCV care cascade among PWID in Puerto Rico. This study aims to describe the HCV
Yesenia Aponte-Meléndez   +7 more
doaj   +1 more source

IspH–RPS1 and IspH–UbiA: “Rosetta stone” proteins

open access: yesChemical Science, 2015
IspH forms fusion hybrids with RPS1 as well as UbiA, examples of Rosetta stone proteins.
Guodong Rao   +4 more
openaire   +3 more sources

Seepage failure prediction of breakwater using an unresolved ISPH-DEM coupling method enriched with Terzaghi’s critical hydraulic gradient

open access: yesAdvanced Modeling and Simulation in Engineering Sciences, 2023
This study develops a new numerical simulation model for rubble mound failure prediction caused by piping destruction under seepage flows. The piping has been pointed out as a significant cause of breakwater failure during tsunamis.
Kumpei Tsuji   +2 more
doaj   +1 more source

The impact of COVID-19 on people who inject drugs in New York City: increased risk and decreased access to services

open access: yesHarm Reduction Journal, 2021
Background While people who inject drugs (PWID) are vulnerable to the adverse outcomes of events like COVID-19, little is known regarding the impact of the current pandemic on PWID.
Yesenia Aponte-Melendez   +5 more
doaj   +1 more source

Comparison of different iterative schemes for ISPH based on Rankine source solution

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2017
Smoothed Particle Hydrodynamics (SPH) method has a good adaptability for the simulation of free surface flow problems. There are two forms of SPH. One is weak compressible SPH and the other one is incompressible SPH (ISPH).
Xing Zheng, Qing-wei Ma, Wen-yang Duan
doaj   +1 more source

Iron-Sulfur Cluster Enzymes of the Methylerythritol Phosphate Pathway: IspG and IspH. [PDF]

open access: yesBiochemistry
Iron-sulfur cluster (Fe-S) enzymes catalyze important biological processes in cellular metabolism. They evolved in the preoxic world and are oxygen sensitive; biology has therefore evolved a range of mechanisms to protect them from oxidative damage. The 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis has two Fe-S enzymes ...
Douw A   +3 more
europepmc   +5 more sources

Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme

open access: yesComptes Rendus. Chimie, 2023
Our previous research revealed that (E)-4-amino-3-methylbut-2-en-1-yl diphosphate (AMBPP) is one of the best inhibitors of IspH, a [4Fe–4S]-dependent enzyme involved in the methylerythritol phosphate pathway that is a valuable target for the discovery of
Petit, Benoît Eric   +6 more
doaj   +1 more source

Safety, Efficacy, and Ill Intent: Examining COVID-19 Vaccine Perceptions among the New Undervaccinated Moveable Middle in a U.S. Cohort, October 2022

open access: yesVaccines, 2023
Individuals who received their primary vaccine series only (with no subsequent booster) may be a new type of “moveable middle” given their receipt of the original COVID-19 vaccination.
Rachael Piltch-Loeb   +6 more
doaj   +1 more source

ISPH wave simulation by using an internal wave maker [PDF]

open access: yesCoastal Engineering, 2015
In this paper, a non-reflection internal wave maker algorithm is included in the incompressible Smoothed Particle Hydrodynamics (ISPH) model for the wave simulations. A momentum source term derived from the Boussinesq equations is employed and added into the Lagrangian form of Navier–Stokes equations for the wave generations that are not affected by ...
Liu, X., Lin, P., Shao, S.
openaire   +2 more sources

ISPH–PBD: coupled simulation of incompressible fluids and deformable bodies [PDF]

open access: yesThe Visual Computer, 2019
We present an efficient and stable method for simulating the two-way coupling of incompressible fluids and deformable bodies. In our method, the fluid is represented by particles, and simulated using divergence-free incompressible smoothed-particle hydrodynamics (ISPH).
Nadine Abu Rumman   +4 more
openaire   +4 more sources

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