Results 11 to 20 of about 211 (134)

La atorvastatina protege las neuronas gabérgicas y dopaminérgicas del sistema nigroestriatal en un modelo experimental de isquemia cerebral focal transitoria en ratas

Biomédica: revista del Instituto Nacional de Salud, 2014
Introducción. La isquemia cerebral es la tercera causa de muerte y la primera de discapacidad permanente en el mundo. La atorvastatina es un fármaco neuroprotector prometedor para el tratamiento de la apoplejía; sin embargo, su acción sobre las ...
Angélica María Sabogal, Cesar Augusto Arango, Gloria Patricia Cardona, Ángel Enrique Céspedes   +3 more
doaj   +3 more sources

Evaluación de la diásquisis transcallosa en un modelo murino de isquemia cerebral focal

Colombia Medica, 2016
Objetivo:Evaluar los cambios exofocales transcallosos después de lesión isquémica focal en ratas, mediante marcación inmunohistoquímica con el anticuerpo monoclonal anti-NeuN (Mouse Anti-Neuronal Nuclei).Métodos:Se intervinieron 28 ratas machos Wistar adultas.
Laura Potes, John Umbarila, Cesar Augusto Arango-Dávila, Beatriz E Munoz, Daniel Manrique Castaño   +4 more
openaire   +2 more sources

Hypoxia–ischemia is not an antecedent of most preterm brain damage: the illusion of validity

Developmental Medicine &Child Neurology, Volume 60, Issue 2, Page 120-125, February 2018., 2018
Brain injury in preterm newborn infants is often attributed to hypoxia–ischemia even when neither hypoxia nor ischemia is documented, and many causative speculations are based on the same assumption. We review human and animal study contributions with their strengths and limitations, and conclude that – despite all the work done in human fetal ...
Floyd Gilles, Pierre Gressens, Olaf Dammann, Alan Leviton   +3 more
wiley   +1 more source

Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes

Oxidative Medicine and Cellular Longevity, Volume 2015, Issue 1, 2015., 2015
Mitochondria are essential organelles for eukaryotic homeostasis. Although these organelles possess their own DNA, the vast majority (>99%) of mitochondrial proteins are encoded in the nucleus. This situation makes systems that allow the communication between mitochondria and the nucleus a requirement not only to coordinate mitochondrial protein ...
Fernanda Marques da Cunha, Nicole Quesada Torelli, Alicia J. Kowaltowski, Adriana Maria Cassina   +3 more
wiley   +1 more source

Otology versus Otosociology

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Otology concerns the biological study of ear alterations and diseases, solely. So, the diagnosis of audiovestibular diseases tends to be idiopathic or is based on theoretical concepts such as idiopathic sudden deafness, Ménière disease, benign paroxysmal positional vertigo, tinnitus, hyperacusis, or idiopathic facial paralysis.
Miguel A. Lopez-Gonzalez, Georgina Cherta, Jose A. Nieto, Francisco Esteban, C. Y. Chien, M. Sone, C.-H. Wang   +6 more
wiley   +1 more source

Inflammatory Animal Model for Parkinson′s Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons

International Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in Parkinson′s disease (PD). The implication of neuroinflammation on this disease was originally established in 1988, when the presence of activated microglia in the substantia nigra (SN) of parkinsonians was reported by McGeer et ...
A. Machado, A. J. Herrera, J. L. Venero, M. Santiago, R. M. de Pablos, R. F. Villarán, A. M. Espinosa-Oliva, S. Argüelles, M. Sarmiento, M. J. Delgado-Cortés, R. Mauriño, J. Cano, A. Conti, A. Lewén   +13 more
wiley   +1 more source

ACIDENTE VASCULAR CEREBRAL COMO COMPLICAÇÃO EM DOENÇA FALCIFORME SC

Hematology, Transfusion and Cell Therapy, 2021
Introdução: A Doença Falciforme (SS) é considerada de maior risco para vasculopatias crônicas em SNC culminando, geralmente, com eventos de acidente vascular cerebral isquêmico (AVCI).
AC Coletti, SM Luporini, M Pizza, ML Borsato, P Bruniera, ICO Hegg   +5 more
doaj   +1 more source

Avaliação da isquemia cerebral pela respiração mitocondrial: modelo experimental Study of brain ischemia by mitochondrial respiration: experimental model

Arquivos de Neuro-Psiquiatria, 2001
A isquemia cerebral acontece em várias doenças. Um dos fatores críticos para a recuperação de um paciente é a duração do processo isquêmico. A atividade cerebral depende do suprimento de energia, isto sugere que o estudo da função mitocondrial pode ser ...
Carlos Gilberto Carlotti Junior, Benedicto Oscar Colli, João Yano Kazuo   +2 more
doaj   +1 more source

Efecto neurogénico de la copaxona en un modelo de isquemia cerebral focal con reperfusión

, 2021
Las enfermedades cerebro-vasculares son un conjunto de patologías causadas por alteraciones en la irrigación sanguínea ya sea de manera transitoria o permanente, desencadenando una serie de eventos como la excitotoxicidad, apoptosis, inflamación etc.; que conducen a la muerte neuronal. La inmunización con péptidos neurales modificados, como la copaxona,
openaire   +2 more sources

Comparación de la lesión producida en tres modelos animales de isquemia cerebral focal permanente mediante resonancia magnética

Revista de Neurología, 2011
Introduccion. Los modelos animales de isquemia cerebral son indispensables en la investigacion de la patologia cerebrovascular. Actualmente, no existe un modelo experimental que refleje perfectamente la fisiopatologia del ictus, por lo que la seleccion de este es fundamental para una interpretacion correcta de los resultados obtenidos.
Castillo Sánchez, José, Brea López, David, Pérez Mato, María, Ramos Cabrer, Pedro, Agulla Freire, Jesús, Argibay González, Bárbara   +5 more
openaire   +2 more sources