Results 21 to 30 of about 211 (134)

Expression of HSP70 in cerebral ischemia and neuroprotetive action of hypothermia and ketoprofen Expressão de HSP70 na isquemia cerebral e a ação neuroprotetora da hipotermia e do cetoprofeno

Arquivos de Neuro-Psiquiatria, 2010
Heat shock proteins (HSPs) are molecular chaperones that bind to other proteins to shepherd them across membranes and direct them to specific locations within a cell. Several injurious stimuli can induce Hsp70 expression, including ischemia.
Daniela Pretti da Cunha Tirapelli, Carlos Gilberto Carlotti Junior, João Pereira Leite, Luis Fernando Tirapelli, Benedicto Oscar Colli   +4 more
doaj   +1 more source

Guía de recomendaciones en la aplicación de modelos animales para el estudio del ictus

Neurología, 2011
Resumen: Introducción: La búsqueda de una terapia neuroprotectora efectiva para el ictus sigue siendo un reto para investigadores y clínicos.
L. García-Bonilla, A. Rosell, G. Torregrosa, J.B. Salom, E. Alborch, M. Gutiérrez, E. Díez-Tejedor, R. Martínez-Murillo, J. Agulla, P. Ramos-Cabrer, J. Castillo, T. Gasull, J. Montaner   +12 more
doaj   +1 more source

Recommendations guide for experimental animal models in stroke research

Neurología (English Edition), 2011
Introduction: The progress of effective therapies for stroke has become a challenging task for both researchers and clinicians. Some pitfalls in clinical trials might have their origins in the pre-clinical experimental ischaemic models for the evaluation
L. García-Bonilla, A. Rosell, G. Torregrosa, J.B. Salom, E. Alborch, M. Gutiérrez, E. Díez-Tejedor, R. Martínez-Murillo, J. Agulla, P. Ramos-Cabrer, J. Castillo, T. Gasull, J. Montaner   +12 more
doaj   +1 more source

Comparação histopatológica dos efeitos protetores cerebrais de dexmedetomidina e tiopental sobre isquemia cerebral focal em ratos

Brazilian Journal of Anesthesiology, 2016
ResumoEste estudo foi desenhado para investigar se dexmedetomidina e tiopental têm efeitos protetores cerebrais após isquemia cerebral focal em ratos. Trinta ratos da linhagem Sprague Dawley foram randomicamente alocados em três grupos: controle (Grupo C, n=10), dexmedetomidina (Grupo D, n=10) e tiopental (Grupo T, n=10).
Çanakçı, Ebru, Özmen, Sevilay Akalp, Çolak, Mustafa Ferhat, Kürşad, Hüsnü   +3 more
openaire   +1 more source

Accidente cerebrovascular isquémico asociado con ablación por radiofrecuencia de reentrada nodal

Revista Colombiana de Cardiología, 2010
La taquicardia por reentrada nodal es la causa más común de taquicardia supraventricular paroxística; en aquellos pacientes en quienes el manejo farmacológico no es efectivo o deseado la ablación por radiofrecuencia es un excelente método terapéutico ...
Juan C. Díaz Martínez, MD, Carlos E. Durán Rebolledo, MD, Pablo Perafán Bautista, MD, Luis F. Pava Molano, MD   +3 more
doaj   +1 more source

Ataque cerebral agudo isquémico

Revista Ciencias Biomédicas, 2020
La disminución del flujo sanguíneo cerebral por debajo del umbral de autoregulación conlleva a cambios de isquemia y necrosis cerebral, que se traducen en síntomas de disfunción neurológica focal llamado ataque cerebrovascular agudo (ACA) o ictus.
Samir Franco Garcia, Belis Barreiro Pinto   +1 more
doaj   +1 more source

Regional mild hypothermia in the protection of the ischemic brain A hipotermia regional moderada na proteção do encéfalo isquêmico

Acta Cirúrgica Brasileira, 2002
Objective: To demonstrate that mild hypothermia can be a protective element when an ischemic onset occurs in rabbit brains. Methods: A rabbit model of focal ischemia was used to test the protection provided by mild hypothermia regionally produced by ...
Mirto Nelso Prandini, Santino Nunes Lacanna, Paulo Roberto Valente, João Norberto Stavale   +3 more
doaj   +1 more source

Transplantation of mouse embryonic stem cell after middle cerebral artery occlusion Transplante de células-tronco embrionárias de camundongo após a oclusão da artéria cerebral média

Acta Cirúrgica Brasileira, 2012
PURPOSE: Stem cell transplantation has been extensively studied as individual therapies for ischemic stroke. The present investigation is an initial effort to combine these methods to achieve increased therapeutic effects after brain ischemia.
Lee Tae-Hoon, Lee Yoon-Seok
doaj   +1 more source

Scintigraphic imaging of focal hypoxic tissue: development and clinical applications of 123I-IAZA

Brazilian Archives of Biology and Technology, 2002
Affected tissues in a number of diseases, including cancer, stroke, cardiac infarction and diabetes, develop focal tissue hypoxia during their progression. The presence of hypoxic tissue may make the disease refractory to therapy, as in the case of solid
Leonard I. Wiebe, Alexander J. B. McEwan
doaj   +1 more source

Cambios de los receptores de benzodiazepinas en la sustancia negra como consecuencia de lesión del territorio de la arteria cerebral media en un modelo experimental de isquemia con reperfusión en ratas

Iatreia, 2005
Se han demostrado cambios remotos o exofocales en la sustancia negra, en modelos experimentales de isquemia focal, con compromiso de la corteza cerebral y el estriado dorsolateral.
Hernán J. Pimienta J., L. Rocha, C. Arango Dávila   +2 more
doaj