Results 1 to 10 of about 10,645 (216)

An Integrated Score and Nomogram Combining Clinical and Immunohistochemistry Factors to Predict High ISUP Grade Clear Cell Renal Cell Carcinoma [PDF]

Frontiers in Oncology, 2018
Objective: The International Society of Urological Pathology (ISUP) has proposed a grading system to classify renal cell carcinoma (RCC). However, classification using biopsy specimens remains problematic and, consequently, the accuracy of a biopsy-based
Yu Wei, Ding-Wei Ye, Hai-Liang Zhang
exaly   +4 more sources

Tumour Volume Independently Predicts Metastasis in ISUP 2 Prostate Cancer. [PDF]

Cancers (Basel)
Background and Objectives: The outcomes for patients with localised prostate cancer are variable, even within defined tumour grades or clinical risk groups. Identifying features associated with disease aggression is imperative in contemporary PCa research.
Homewood D, Yanada B, Mullholland C, Lyttwin B, Mangat P, Botha T, Sathianathen N, Thalmann GN, Corcoran NM, Furrer MA.   +9 more
europepmc   +4 more sources

The Association of Quantitative PSMA PET Parameters With Pathologic ISUP Grade: An International Multicenter Analysis [PDF]

European Journal of Nuclear Medicine and Molecular Imaging
Abstract Purpose To assess if PSMA PET quantitative parameters are associated with pathologic ISUP grade group (GG) and upgrading/downgrading. Methods PCa patients undergoing radical prostatectomy with or without pelvic lymph node dissection staged with preoperative PSMA PET
Jules Lavalaye, Timo F W Soeterik, Jean-Paul A van Basten   +2 more
exaly   +11 more sources

Florastamin Uptake on PSMA PET/CT as an Imaging Biomarker of Tumor Aggressiveness in Prostate Cancer [PDF]

Diagnostics
Background: This study aimed to evaluate the association between the uptake on F-18 florastamin PET/CT, which targets the prostate-specific membrane antigen (PSMA), and the histopathological grade of the primary tumor in newly diagnosed prostate cancer ...
Yeongjoo Lee, Joo Hyun O, Seunggyun Ha, Chansoo Park, Dongho Shin, Hyong Woo Moon, Ji Youl Lee   +6 more
doaj   +2 more sources

4Kscore as a Pre-MRI Reflex Test for Men with PSA 1.80–2.99 ng/ml in the Göteborg-2 Prostate Cancer Screening Trial [PDF]

European Urology Open Science
Background: Lowering the prostate-specific antigen (PSA) cut-off from 3.0 to 1.8 ng/ml in prostate cancer (PCa) screening would improve diagnostic yield but substantially increase the number of men undergoing diagnostic work-up.
Fredrik Möller, Andreas Josefsson, Marianne Månsson, Sigrid Carlsson, Hans Lilja, Vasiliki Spyratou, Jonas Wallström, Jonas Hugosson, Rebecka Arnsrud Godtman   +8 more
doaj   +2 more sources

Systematic versus perilesional sampling in transperineal MRI-fusion biopsy: is perilesional sampling ready for prime time? A high-volume center analysis [PDF]

World Journal of Surgical Oncology
Background Multiparametric MRI has improved prostate cancer (PCa) diagnostics. The current standard combines MRI-targeted fusion biopsy (TB) with 12-core systematic biopsy (SB); current guidelines allow replacing SB with perilesional sampling (PB ...
Agneta Seebold, Thomas Büttner, Jörg Ellinger, Glen Kristiansen, Marit Bernhardt, Alexander Isaak, Christian Hoffmann, Julian A. Luetkens, Manuel Ritter, Philipp Krausewitz   +9 more
doaj   +2 more sources

Focal Therapy for Prostate Cancer: A Treatment Option Reserved for the Ideal Candidate? [PDF]

International Brazilian Journal of Urology
Objectives: To evaluate outcomes of FT (HIFU or cryotherapy) in prostate cancer (PCa) patients who do not meet the ideal focal therapy candidate profile, assessing whether expanding selection criteria beyond traditional parameters is safe. Materials and
Daniele Cignoli, João Paulo Barbosa de Oliveira, Andrea Rodriguez-Serrano, David Lopez, Armando Stabile, Andrea Salonia, Alberto Briganti, Francesco Montorsi, Giovanni La Croce, Michele Catellani, Paolo Barzaghi, Marco Roscigno, Luigi Filippo Da Pozzo, Yenny Arroyo Rojas, Julio César González Brambila, Camille Lanz, Eric Barret, Petr Macek, Xavier Cathelineau, Lara Rodriguez-Sanchez   +19 more
doaj   +3 more sources

Minimum ADC outperforms PSA and PSA density for predicting ISUP grade group in prostate cancer: a retrospective study of 192 patients undergoing radical prostatectomy [PDF]

Frontiers in Oncology
BackgroundApparent diffusion coefficient (ADC) derived from diffusion-weighted imaging (DWI) has been proposed as a quantitative biomarker of prostate cancer aggressiveness, and an inverse relationship between ADC and Gleason score has been reported ...
Katarzyna Skrobisz, Weronika Bernard, Rafał Bromirski, Karolina Nowak, Anna Glińska, Wojciech Połom, Joanna Pieńkowska   +6 more
doaj   +2 more sources

ISUP Grade Upgrade Prediction After Radical Prostatectomy: Role of Luteinizing Hormone to Testosterone Ratio

BJUI Compass
Purpose This study aimed to evaluate the predictive value of the luteinizing hormone to testosterone (LH/T) ratio in postoperative International Society of Urological Pathology (ISUP) grade upgrading following radical prostatectomy. Materials and Methods
Bianjiang Liu, Ruizhe Zhao
exaly   +2 more sources

New Age and Environment: New Forms of Spirituality and Lifestyle in the Context of Secularization?

Religions, 2023
From the middle of the 20th century, the rise of anthropocentric beliefs partly inherited from the Abrahamic religions led to a change in mentality about ecosystems.
Tiago Pinto, Helena Vilaça
doaj   +1 more source