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Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Tujuan penelitian ini adalah untuk mengetahui apakah terdapat perbedaan atau bias pada data unidimensional second order namun sering diperlakukan sebagai unidimensional hanya pada tingkat pertama atau first order, serta mengetahui sejauh mana pengaruh ...
Puti Febrayosi
doaj +1 more source
The Unfairness of Popularity Bias in Book Recommendation [PDF]
Recent studies have shown that recommendation systems commonly suffer from popularity bias. Popularity bias refers to the problem that popular items (i.e., frequently rated items) are recommended frequently while less popular items are recommended rarely or not at all. Researchers adopted two approaches to examining popularity bias: (i) from the users'
arxiv
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
O funcionamento diferencial dos itens Differential item functioning
A dificuldade de um item deveria ser uma propriedade independentemente de uma população em particular, da mesma forma que a habilidade de uma pessoa deveria ser uma característica sem referência a qualquer conjunto particular de itens.
Fermino Fernandes Sisto
doaj +1 more source
The Influence of Active Removal from Working Memory on Serial Dependence
Flexible control of the contents of working memory (WM) includes removing no-longer-relevant information. Although simply withdrawing attention offers a “passive” mechanism, empirical findings suggest that it is also possible to actively remove ...
Jiangang Shan, Bradley R. Postle
doaj +1 more source
Popularity Bias in Collaborative Filtering-Based Multimedia Recommender Systems [PDF]
Multimedia recommender systems suggest media items, e.g., songs, (digital) books and movies, to users by utilizing concepts of traditional recommender systems such as collaborative filtering. In this paper, we investigate a potential issue of such collaborative-filtering based multimedia recommender systems, namely popularity bias that leads to the ...
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Mitigating Frequency Bias in Next-Basket Recommendation via Deconfounders [PDF]
Recent studies on Next-basket Recommendation (NBR) have achieved much progress by leveraging Personalized Item Frequency (PIF) as one of the main features, which measures the frequency of the user's interactions with the item. However, taking the PIF as an explicit feature incurs bias towards frequent items.
arxiv