Results 51 to 60 of about 225,155 (290)

The application of measurement theory to tests in mathematics: a study of the goodness-of-fit of rasch model to the alis mathematics test [PDF]

open access: yes, 2003
The scores provided by the International Test of Developed Ability (ITDA) have been used as an alternative baseline for comparing the progress of students in the A-level Information System (ALIS) project of U.K.
Kwan, Siu Kam
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Difficulty of Summarization Items for Japanese Learners: Effects of Passages, Distractors, and Response Formats

open access: yesFrontiers in Education, 2020
This study aims to examine factors affecting the difficulty of summarization items for Japanese learners. In the process of item development, creating a connection between cognitive features related to target construct and the difficulty of test items is
Takahiro Terao
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Rasch Analysis of the Disability Acceptance Scale for Individuals With Cerebral Palsy

open access: yesFrontiers in Neurology, 2019
Background: Acceptance of disability has been considered an important factor in rehabilitation procedures. The Disability Acceptance Scale (DAS) was used in a panel survey, and it is likely that this scale will be increasingly used.
Eun-Young Park
doaj   +1 more source

Item infit statistics and item difficulty rating (logits).

open access: yes, 2014
Item infit statistics and item difficulty rating (logits).
Minbin Yu (380723)   +8 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Automatic Generation of Number Series Reasoning Items of High Difficulty

open access: yesFrontiers in Psychology, 2019
Number series reasoning items have been frequently used in educational assessment. This study reviewed the previous literature investigating features relating to item difficulty and developed a new automatic generator for number series reasoning items ...
Luning Sun, Yanan Liu, Fang Luo
doaj   +1 more source

Item passing rates (item difficulty) of the HAST subtests (N = 40).

open access: yes, 2023
Item passing rates (item difficulty) of the HAST subtests (N = 40).
Ágnes Lukács (3612704)   +1 more
core   +1 more source

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