Results 51 to 60 of about 467,824 (303)

Quality Assurance of Multiple-Choice Questions Test Through Item Analysis

open access: yesLife and Science, 2023
Objective: To analyze the value of in use multiple choice questions of ophthalmology by finding discrimination index, distractor efficiency and difficulty index. Study Design: Cross-sectional study.
Mashood -uz-Zafar Farooq, Shama Mashood
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Optimal Auctions vs. Anonymous Pricing

open access: yes, 2015
For selling a single item to agents with independent but non-identically distributed values, the revenue optimal auction is complex. With respect to it, Hartline and Roughgarden (2009) showed that the approximation factor of the second-price auction with
Alaei, Saeed   +4 more
core   +1 more source

Integrated Testlets and the Immediate Feedback Assessment Technique [PDF]

open access: yes, 2013
The increased use of multiple-choice (MC) questions in introductory-level physics final exams is largely hindered by reservations about its ability to test the broad cognitive domain that is routinely accessed with typical constructed-response (CR ...
Slepkov, Aaron D.
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Analisis Butir Soal Ujian Semester Ganjil Pelajaran Kimia Kelas XI IPA SMA Negeri 10 Pekanbaru Tahun Pelajaran 2013/2014 [PDF]

open access: yes, 2015
This study aimed to determine the quality of odd semester exam chemistry lesson for class XI IPA SMAN 10 Pekanbaru in academic year 2013/2014 viewed from relevance of indicator item and distribution of the cognitive taxonomy Bloom, level of difficulty ...
Copriady, J. C. (Jimmi)   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

More Social Needs Endorsed by Caregivers of Young Children Experiencing Everyday Discrimination [PDF]

open access: yes, 2018
Background: Both discrimination and social needs are underlying risk factors for poor health outcomes; however, there are no studies looking at how feelings of discrimination impact reporting of social needs in the pediatric health care setting ...
Abatemarco, PhD, MSW, Diane   +5 more
core   +1 more source

Teaching and learning evidence-based medicine: cross-sectional survey investigating knowledge and attitudes of teachers and learners in primary and secondary care [PDF]

open access: yes, 2007
Evidence-based medicine (EBM) is an important component of quality healthcare and a key part of the curriculum for doctors in training. There have been no previous studies comparing attitudes and knowledge of doctors in primary and secondary care ...
Gemmell, Islay   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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