Results 111 to 120 of about 1,081,470 (322)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Item response theory and the measurement of deprivation: Evidence from PSELL-3 [PDF]
Item Response Theory (IRT) has recently been proposed as a framework to measure deprivation. It allows deriving a latent measure of deprivation from a set of dichotomous observed items of deprivation and analyzing determinants of deprivation.
Fusco, Alessio, Raileanu Szeles, Monica
core
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Item Response Theory Models Applied to Data Allowing Examinee Choice [PDF]
Eric T. Bradlow, Neal Thomas
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Bounds on Quantiles in the Presence of Full and Partial Item Nonresponse [PDF]
Microeconomic surveys are usually subject to the problem of item nonresponse, typically associated with variables like income and wealth, where confidentiality and/or lack of accurate information can affect the response behavior of the individual. Follow
Melenberg, B.+2 more
core +1 more source
Funcionamento diferencial dos itens do Teste Cloze por Opção
This study analyzed the differential item functioning of Teste Cloze por Opção EM/U that assess collectively reading comprehension. The subjects were 489 students.
Maria Cristina Rodrigues Azevedo Joly+1 more
doaj
Item Response Theory and Health Outcomes Measurement in the 21st Century [PDF]
Ron D. Hays+2 more
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Item-Response-Theorie: Prozeßmodelle
Digitalisierte Ausgabe 2019. Gedruckt erschienen im Handbuch Quantitative Methoden (1996), hrsg. von Edgar Erdfelder, Rainer Mausfeld, Thorsten Meiser und Georg Rudinger, beim Beltz-Verlag (Weinheim), ISBN 3-621-27280-1.
openaire +2 more sources