Results 61 to 70 of about 12,425,968 (292)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Using the area between two item response functions to index differential item functioning : a generalized approach [PDF]

open access: yes, 1994
The area between two item response functions was used to construct two indicators of differential item functioning. The first indicator was designed from the integral of the difference of the two response functions across six standard deviations of ...
Penny, James A.   +1 more
core  

Generalizability theory and item response theory [PDF]

open access: yes, 2012
Item response theory is usually applied to items with a selected-response format, such as multiple choice items, whereas generalizability theory is usually applied to constructed-response tasks assessed by raters.
Glas, Cees A.W.
core   +3 more sources

Relationship between connectedness with nature and environmental beliefs

open access: yesInnoeduca, 2019
Connectedness to nature is defined as a feeling of belonging to natural environment. Studies over relationship between connectedness and environmental beliefs from the New Paradigm Environmental Scale, show low-mean correlation values.
Antonio Matas Terrón
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Item Response Theory Approach to the Maintenance of Standards in Public Examinations in England [PDF]

open access: yes, 2011
Every year outcomes from public examinations in the UK rise: politicians congratulate pupils on their hard earned achievement; the media questions whether this achievement is real; those responsible for administrating the examinations defend their ...
WHEADON, CHRISTOPHER,BRIAN   +1 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Item Response Theory Model for Understanding Item Non- Response in Ghanaian Surveys [PDF]

open access: yes, 2014
This paper explores four Item Response Theory (IRT) models to determine the most appropriate forunderstanding item non-response. The selected IRT model was used to identify among five categories of surveyquestions, the most difficult to answer by ...
Amoamah, Martin Owusu   +2 more
core   +1 more source

ANALISIS RESPONS BUTIR PADA TES BAKAT SKOLASTIK

open access: yesJurnal Psikologi Undip, 2018
This study aims to analyze the characteristics of the Scholastic Aptitude Test (SAT), consisting of both verbal and numerical subtests. We used a descriptive quantitative approach by describing the characteristics of SAT based on the degree of item ...
Farida Agus Setiawati   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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