Results 61 to 70 of about 12,812,359 (296)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Item response theory calibration results.

, 2019
Item response theory calibration results.
Janhavi Ajit Vaingankar (2164432), Mei Fen Chan (7109498), Julian Thumboo (427858), Elenore Judy Uy (6682673), Dianne Carrol Bautista (4839666), Geok Ling Lee (6469283), Terrance Siang Jin Chua (3170211), Nisha Kumar (6682676), Yin Bun Cheung (17908), Xiaohui Xin (4839663), Yunshan Xiao (5753005), Yu Heng Kwan (5066684), Mythily Subramaniam (446121)   +12 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship between connectedness with nature and environmental beliefs

Innoeduca, 2019
Connectedness to nature is defined as a feeling of belonging to natural environment. Studies over relationship between connectedness and environmental beliefs from the New Paradigm Environmental Scale, show low-mean correlation values.
Antonio Matas Terrón
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

ANALISIS RESPONS BUTIR PADA TES BAKAT SKOLASTIK

Jurnal Psikologi Undip, 2018
This study aims to analyze the characteristics of the Scholastic Aptitude Test (SAT), consisting of both verbal and numerical subtests. We used a descriptive quantitative approach by describing the characteristics of SAT based on the degree of item ...
Farida Agus Setiawati, Rita Eka Izzaty, Veny Hidayat   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A practical guide to item bank calibration with multiple matrix sampling

International Journal of Assessment Tools in Education
When it is required to estimate item parameters of a large item bank, Multiple Matrix Sampling (MMS) design provides an efficient way while minimizing the test burden on students. The current study exemplifies how to calibrate a large item pool using MMS
Güneş Ertaş, Serkan Arıkan, Eren Can Aybek   +2 more
doaj   +1 more source