Results 11 to 20 of about 41,330 (277)

Pediatric ITP: is it different from adult ITP? [PDF]

Hematology, 2018
AbstractImmune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms: childhood ITP and adult ITP. This division is based largely on the presumption that childhood ITP is often benign and self-limited, whereas ITP in adults tends to be more chronic and difficult to treat.
Amanda B. Grimes, Jenny M. Despotovic
openaire   +4 more sources

Management of Adult Patients with Immune Thrombocytopenia (ITP): A Review on Current Guidance and Experience from Clinical Practice

Journal of Blood Medicine, 2021
Fei Song,1,2 Hanny Al-Samkari2,3 1Department of Medicine, Massachusetts General Hospital, Boston, MA, USA; 2Harvard Medical School, Boston, MA, USA; 3Division of Hematology, Massachusetts General Hospital, Boston, MA, USACorrespondence: Hanny Al ...
Song F, Al-Samkari H
doaj   +2 more sources

Assessment and Management of Immune Thrombocytopenia (ITP) in the Emergency Department: Current Perspectives

Open Access Emergency Medicine, 2022
Tony Zitek,1,2 Luke Weber,1 Dominique Pinzon,1 Nicole Warren1– 3 1Department of Emergency Medicine, Mount Sinai Medical Center, Miami Beach, FL, USA; 2Department of Emergency Medicine, Herbert Wertheim College of Medicine at Florida International ...
Zitek T, Weber L, Pinzon D, Warren N
doaj   +2 more sources

Is ITP a thrombophilic disorder? [PDF]

American Journal of Hematology, 2015
Immune thrombocytopenia (ITP) represents the epitome of acquired bleeding diseases for the hematologist. Stemming from the interest for the safety of thrombopoietin‐receptor agonists (TPO‐ra) romiplostim and eltrombopag, recent data have investigated if thrombotic risk is also increased in this disorder.
F. Rodeghiero
openaire   +4 more sources

SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP

Blood, 2022
Key Points SARS-CoV-2 vaccines are generally safe in patients with preexisting ITP but thrombocytopenia exacerbation may occur and requires monitoring. Splenectomy and past use of 5 or more therapies predict higher risk of worsening thrombocytopenia in ...
Eun-Ju Lee, Marina Beltrami-Moreira, H. Al‐Samkari, A. Cuker, J. DiRaimo, T. Gernsheimer, A. Kruse, C. Kessler, C. Kruse, A. Leavitt, A. Lee, H. Liebman, A. Newland, A. Ray, M. Tarantino, J. Thachil, D. Kuter, D. Cines, J. Bussel   +18 more
semanticscholar   +2 more sources

Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives

Annals of Hematology, 2022
Chronic primary immune thrombocytopenia (ITP) can today benefit from multiple therapeutic approaches with proven clinical efficacy, including rituximab, thrombopoietin receptor agonists (TPO-RA), and splenectomy.
N. Vianelli, G. Auteri, F. Buccisano, V. Carrai, E. Baldacci, C. Clissa, D. Bartoletti, G. Giuffrida, D. Magro, E. Rivolti, D. Esposito, G. Podda, F. Palandri   +12 more
semanticscholar   +1 more source

Novel Therapies to Address Unmet Needs in ITP

Pharmaceuticals, 2022
Primary immune thrombocytopenia (ITP) is an autoimmune disorder that causes low platelet counts and subsequent bleeding risk. Although current corticosteroid-based ITP therapies are able to improve platelet counts, up to 70% of subjects with an ITP ...
M. Mingot-Castellano, J. Bastida, Gonzalo Caballero-Navarro, Laura Entrena Ureña, T. González‐López, J. González-Porras, N. Butta, M. Canaro, Reyes Jiménez-Bárcenas, María Del Carmen Gómez Del Castillo Solano, B. Sánchez‐González, C. Pascual-Izquierdo, On Behalf Of The Gepti   +12 more
semanticscholar   +1 more source

Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Open Forum Infectious Diseases, 2021
Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and ...
Muzamil Jawed, A. Khalid, Mayer Rubin, Ramsha Shafiq, Nail Cemalovic   +4 more
semanticscholar   +1 more source

Platelets in ITP: Victims in Charge of Their Own Fate?

Cells, 2021
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved, but at least involve autoantibody-dependent and/or cytotoxic T cell mediated platelet ...
V. Nelson, Anne-Tess C Jolink, S. Amini, J. Zwaginga, T. Netelenbos, J. Semple, L. Porcelijn, M. de Haas, M. Schipperus, R. Kapur   +9 more
semanticscholar   +1 more source

Bleeding Diseases in Orthopedic Clinical Approach [PDF]

Гений oртопедии, 2020
Aim Bleeding diseases are rarely studied as complications of an orthopedic surgical procedure with postsurgical bleeding. This study aims to present a retrospective cohort-study about the approach to bleeding disorders in an ordinary orthopedic clinic ...
Kadri Yildiz, Vahit Yildiz
doaj   +1 more source