Results 81 to 90 of about 30,043 (228)
Highlights: 1. This study was the first to analyze the therapeutic response in children with ITP at Dr. Soetomo General Academic Hospital, Surabaya. 2. This study analyzed the response of platelet count and indices, including MPV, PDW, P-LCR, and PCT to ...
Regina Rania Cahya Kusumaningrum - +3 more
doaj +1 more source
Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand +2 more
wiley +1 more source
Well‐characterized, chemically synthesized molecules related to LGD‐4033 metabolism were used as analytical standards for the analysis of LGD‐4033 post‐administration urine samples. This approach offered further insights into LGD‐4033 metabolism, providing solid experimental proof for the structure of important previously reported metabolites and ...
Yiannis S. Angelis +5 more
wiley +1 more source
ABSTRACT Background Myeloma bone disease (MBD) is a devastating complication of multiple myeloma (MM) and a primary cause of disability in affected patients. Its pathogenesis is driven by an imbalance in bone remodeling, largely attributed to the overexpression of C‐C motif chemokine ligand 3 (CCL3). While both bortezomib and statins have been reported
Fujun Qu +6 more
wiley +1 more source
Design, development, and characterization of an aerosol conditioning device. Removes aqueous vapor fraction of atomized aerosols.
openaire +1 more source
Repeat Ultrasonographic Examinations Reveal Accessory Spleen in a Case with Relapse ITP [PDF]
Ahmet Sarıcı +3 more
openalex +1 more source
Real‐Time Deep‐Learning Image Reconstruction and Instrument Tracking in MR‐Guided Biopsies
ABSTRACT Background Transrectal in‐bore MR‐guided biopsy (MRGB) is accurate but time‐consuming, limiting clinical throughput. Faster imaging could improve workflow and enable real‐time instrument tracking. Existing acceleration methods often use simulated data and lack validation in clinical settings.
Constant R. Noordman +5 more
wiley +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
ABSTRACT The advancement of T cell engineering has significantly transformed the field of cancer immunotherapy. In particular, T cells equipped with modified T cell receptors present a promising therapeutic strategy, especially for addressing solid tumors.
Mario Frezzini, Daniele Narzi
wiley +1 more source
Megakaryocyte apoptosis in immune thrombocytopenia
The mechanisms of platelet underproduction in immune thrombocytopenia (ITP) remain unknown. While the number of megakaryocytes is normal or increased in ITP bone marrow, further studies of megakaryocyte integrity are needed.
John R. Vrbensky +7 more
doaj +1 more source

