Results 131 to 140 of about 47,734 (283)

Accumulation of 3-Ketosteroids Induced by Itraconazole in Azole-Resistant ClinicalCandida albicansIsolates [PDF]

, 1999
Patrick Marichal, J. Gorrens, Leen Laurijssens, Karen Vermuyten, Carl Van Hove, Ludo Le Jeune, Peter Verhasselt, Dominique Sanglard, Μ. Borgers, Frans C.�S. Ramaekers, Frank C. Odds, H. Vanden Bossche   +11 more
openalex   +1 more source

Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1695-1704, October 2025.
ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed and verified for dordaviprone, a small molecule with antitumor effects in glioma patients. The model was applied to assess the drug–drug interaction (DDI) potential of dordaviprone as a victim of CYP3A4 inhibitors and inducers, and as a perpetrator of CYP3A4, CYP2C8, CYP2D6 ...
Swati Jaiswal, Nikunjkumar K. Patel, Hannah M. Jones, Savannah McFeely, Shamia L. Faison, Tim Tippin, Odin Naderer   +6 more
wiley   +1 more source

Patterns of in vitro activity of itraconazole and imidazole antifungal agents against Candida albicans with decreased susceptibility to fluconazole from Spain [PDF]

, 1995
Joaquín V. Martínez‐Suárez, J. L. Rodríguez-Tudela   +1 more
openalex   +1 more source

Chromoblastomycosis murine model and in vitro test to evaluate the sensitivity of Fonsecaea pedrosoi to ketoconazole, itraconazole and saperconazole [PDF]

, 1996
Nora Cardona‐Castro, Piedad Agudelo‐Flórez, Rodrigo Restrepo‐Molina   +2 more
openalex   +1 more source

Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies

Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
Dominique Mesquita e Silva, Laís de Souza Lacerda, Andrea de Souza Andrioli, Wilson Rodrigues Braz, Lara Melo Campos, Mayara Rodrigues Brandão de Paiva, Frederico Pittella, Rodrigo Luiz Fabri, Guilherme Diniz Tavares   +8 more
wiley   +1 more source

Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions

Journal of Evaluation in Clinical Practice, Volume 31, Issue 7, October 2025.
ABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
N. N. Ngcobo
wiley   +1 more source

Efficacy of intravenous itraconazole against experimental pulmonary aspergillosis

, 1993
Haruko Miyazaki, S Kohno, Yoshitsugu Miyazaki, Koutaro Mitsutake, Kazunori Tomono, Mitsuo Kaku, Hironobu Koga, Kenji Hara   +7 more
openalex   +1 more source

Treatment outcomes in sinonasal aspergillosis in dogs in the United Kingdom: 436 cases (2011‐2021)

Journal of Small Animal Practice, Volume 66, Issue 10, Page 683-692, October 2025.
Objectives A variety of treatment options for sinonasal aspergillosis have been described, encompassing non‐invasive and invasive approaches. To describe the clinical outcomes in dogs treated for sinonasal aspergillosis in the United Kingdom. Materials and Methods A multi‐centre retrospective survey was performed involving 23 referral centres in the ...
C. D. Prior, H. Swales, A. Kortum, N. Reed, M. Sharman, D. Kelly, A. Kent, B. Glanemann, K. Clarke, C. Lea, E. Roberts, N. Bommer, L. Rutherford, A. Tamborini, K. Murphy, D. J. Batchelor, S. Calleja, R. Burrow, P. M. Jamieson, C. Piazza, M. Best, I. Calvo Saiz, I. Elgueta, S. J. Fowlie, C. Shales, C. Gil Morales, E. Lopez, S. Borgonovi, M. Keane, J. Kennils, E. Izaguirre, M. Hernandez‐Perello, N. Lau, A. Paul, A. Ridyard, E. Shelton, A. Farges, G. Specchia, L. Espada, S. Spence, A. Hrovat, N. Van den Steen, S. Tappin, T. H. Sparks, F. Allerton   +44 more
wiley   +1 more source

Effect of Adding Gold Nanoparticles on the Anti-Candidal Activity and Release Profile of Itraconazole from Hydrogels

Applied Sciences
Gold nanoparticles have been identified as a promising avenue for the development of drug carriers, particularly in the context of antimicrobial drug delivery, where limited solubility represents a significant challenge. The ability of gold nanoparticles
Radosław Balwierz, Paweł Biernat, Dawid Bursy, Mariia Shanaida, Katarzyna Kasperkiewicz, Agata Jasińska-Balwierz, Wioletta Ochędzan-Siodłak   +6 more
doaj   +1 more source

Placebo-controlled trial of itraconazole for treatment of acute vaginal candidiasis

, 1993
Gary E. Stein, N. Mummaw
openalex   +1 more source