Results 121 to 130 of about 37,692 (229)
Our case describes a rare lung co‐infection caused by Aspergillus and Mucorales in a 61‐year‐old man with uncontrolled diabetes and chronic kidney disease. The diagnosis was made by BAL PCR and biopsy. Despite antifungal treatment, the patient worsened and died.
Vinay Venugopal +7 more
wiley +1 more source
Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation
We here evaluated the antiesophageal cancer cell activity by the antifungal drug itraconazole. Our results show that μg/mL concentrations of itraconazole potently inhibited survival and proliferation of established (TE-1 and Eca-109) and primary human ...
Zhao-Yu Xing +6 more
core +1 more source
Localized Tracheobronchial Transthyretin Amyloidosis Diagnosed After Hemoptysis: A Case Report
Pulmonary involvement in transthyretin amyloidosis (ATTR) is rare, and tracheobronchial involvement is particularly uncommon. We report localized wild‐type ATTR presenting with hemoptysis and diagnosed by bronchoscopic biopsy showing Congo red‐positive transthyretin deposition. ABSTRACT Pulmonary involvement in transthyretin amyloidosis (ATTR) is rare,
Koichi Inoue +5 more
wiley +1 more source
ABSTRACT Fungal infections pose a significant health burden in Denmark. Increasing global antifungal use and emerging antifungal resistance underscore the need for ongoing characterization of national prescribing trends to inform antifungal stewardship.
Aditya K. Gupta +4 more
wiley +1 more source
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu +7 more
wiley +1 more source
Sporotrichosis Treated With Itraconazole
One case of lymphocutaneous sporotrichosis treated with itraconazole is reported here. Sporothix schenkii was isolated from the lesion and identity was confirmed by culture.
Kundu Pratip Kumar +3 more
core
The number of cases of invasive fungal infections (IFIs) has risen significantly in recent years; therefore, this study developed a sensitive and effective sweeping-micellar electrokinetic chromatography (MEKC) method for the simultaneous determination ...
Lin, Shu-Chiao;Liu, Hsiang-Yin;Lin, Shu-Wen;Yao, Ming;Wu, Un-In;Kuo, Hsiu-Po;Kuo, Ching-Hua +1 more
core +1 more source
Fruquintinib: Mechanism of Action, Clinical, and Translational Science
ABSTRACT Fruquintinib is a highly selective, oral inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3) that was approved, including in China, the United States, and the European Union, for the treatment of previously treated metastatic colorectal cancer (mCRC).
Xiaofei Zhou +7 more
wiley +1 more source
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju +6 more
wiley +1 more source
Zusammenfassung Die unter Federführung der Deutschen Dermatologischen Gesellschaft e. V. (DDG) erstellte S1‐Leitlinie soll Ärzten eine strukturierte Entscheidungsgrundlage für die Versorgung von Patienten mit Tinea capitis bieten und zur Verbesserung der Diagnosesicherheit, Therapieadhärenz und Prävention beitragen.
Peter Mayser +19 more
wiley +1 more source

