Results 131 to 140 of about 34,586 (301)

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Ultrasound–triggered tumor‐selective nitric oxide release enhances tumor penetration of antibody–conjugated nanomedicine

Interdisciplinary Medicine, EarlyView.
Ultrasound‐triggered nitric oxide release from S‐nitrosated hyaluronic acid (HA‐SNO) induces tumor vasodilation and disrupts the vascular barrier, potently enhancing the intratumoral penetration of antibody‐conjugated nanomedicines. Abstract The tumor vascular barrier restricts the penetration of antibody‐conjugated nanomedicine, severely limiting its ...
Xiaodong Wang, Ruifeng Duan, Xin Chen, Tongjun Liu, Zhilin Liu   +4 more
wiley   +1 more source

Upper Bounds on the Minimum Size of Feedback Arc Set of Directed Multigraphs With Bounded Degree

Journal of Graph Theory, EarlyView.
ABSTRACT An oriented multigraph is a directed multigraph without directed 2‐cycles. Let fas ( D ) $\text{fas}(D)$ denote the minimum size of a feedback arc set in an oriented multigraph D $D$. In several papers, upper bounds for fas ( D ) $\text{fas}(D)$ were obtained for oriented multigraphs D $D$ with maximum degree upper‐bounded by a constant ...
Gregory Gutin, Hui Lei, Anders Yeo, Yacong Zhou   +3 more
wiley   +1 more source

Estimating Quality-of-Service in Urban Vehicular Networks Through Machine Learning

IEEE Access
Machine Learning (ML) has emerged as a promising tool for addressing complex challenges in multiple domains. In the context of Vehicular Ad-Hoc Networks (VANETs), ML has gained much more attention due to its ability to solve major known problems in areas
Duarte Dias, Miguel Luis, Pedro Rito, Susana Sargento   +3 more
doaj   +1 more source

Targeted metabolomics reveals the optimal harvest time of Cabernet Sauvignon grapes in an emerging high‐altitude tropical region

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Climate change has driven the expansion of viticulture in high‐altitude tropical regions. The dynamics of grape ripening and its metabolic profile are influenced by climatic conditions. This study aimed to identify the optimal harvest period for Cabernet Sauvignon grapes cultivated in an emerging Brazilian high‐altitude region using
Laura O. Lago, Rafaela D. Silveira, Vanessa T. da Rosa, Luana P. Mallmann, Mairon M. da Silva, Aline C.T. Biasoto, Juliane E. Welke   +6 more
wiley   +1 more source

Postoperative Weight Gain, Due to Fluid Retention After Ovarian Cancer Surgery—How Much Is too Much?

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Postoperative complications after cytoreductive surgery in ovarian cancer patients are associated with impaired survival. Here, we investigated the association between postoperative weight gain due to fluid retention and the development of complications and anastomotic leakage (AL).
Eva K. Egger, Melisa Delen, Hanno Matthaei, Laura Tascon Padron, Carolin Schröder, Milka Marinova, Dominique Koensgen, Alexander Mustea   +7 more
wiley   +1 more source

Genomic structure and ex situ conservation of the North American grapevine Vitis labrusca

PLANTS, PEOPLE, PLANET, EarlyView.
The North American wild grapevine species Vitis labrusca is an important source of disease resistance and climate resilience traits for breeding new grapevine cultivars. To ensure its continued use in breeding, V. labrusca must be accurately identified and genetically diverse material must be conserved.
Zoë Migicovsky, Clay Elzinga, Mia C. Lauzon, Thomas Connor, Kylie DeViller, Claire Dinn, Grace M. Earle, Emma Hockley, Olivia Lennon, Lillian A. Ricker, Peter M. Roberts, Katrina M. Robinson, Aditi Sharma, Paris N. Spencer, Sammy Stockdale, Liam L. Tingley, Annelies Yates, Jason P. Londo, Peter Cousins   +18 more
wiley   +1 more source

Aptamer sgc8-Modified PAMAM Nanoparticles for Targeted siRNA Delivery to Inhibit BCL11B in T-Cell Acute Lymphoblastic Leukemia

International Journal of Nanomedicine
Xiangbo Zeng,1,2,* Dingrui Nie,1,3,* Zhen Liu,2 Xueting Peng,1 Xianfeng Wang,1 Kangjie Qiu,1 Shuxin Zhong,1 Ziwei Liao,4 Xianfeng Zha,1,5 Yangqiu Li,1,2 Chengwu Zeng1 1Key Laboratory for Regenerative Medicine of Ministry of Education, Institute ...
Zeng X, Nie D, Liu Z, Peng X, Wang X, Qiu K, Zhong S, Liao Z, Zha X, Li Y, Zeng C   +10 more
doaj  

Digital Twin‐Based Optimization of Service Availability in LEO Mega Constellations Considering Handover Delays in Open RAN

International Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT As non‐terrestrial networks (NTNs) become integral to future 6G systems, ensuring seamless connectivity and service continuity over low Earth orbit (LEO) satellite constellations is essential. This work investigates the impact of open radio access network (RAN) functional splits on handover performance in NTNs, focusing on minimizing service ...
Siva Satya Sri Ganesh Seeram, Luca Feltrin, Mustafa Ozger, Cicek Cavdar   +3 more
wiley   +1 more source

Influence of Higher Tramp Element Level on the Weldability of Automotive Steels

steel research international, EarlyView.
The use of green recycled steels is constantly expanding in the automotive industry. The increase in tramp elements resulting from the recycling of steel is problematic. Tramp elements can lead to a negative influence on the weldability. To understand the influence, the welding properties of three green steels are characterized. The potential limits of
Elias Gebhard Vogt, Patrick Veyel, Lars Gebel, Christian Meyer, Robert Thomas, Michael Thomas, Christoph Herrmann   +6 more
wiley   +1 more source