Results 11 to 20 of about 4,726 (262)
Addressing Knowledge Gaps in ITSM Practice with “Learning Digital Commons”: A Case Study [PDF]
Information Systems FrontiersInformation Technology Service Management (ITSM) constitutes a suite of specialized organizational capabilities aimed at optimizing the value derived from IT services. The practice of ITSM encompasses a range of complementary frameworks.
M. Ramakrishnan +3 more
semanticscholar +3 more sources
The Application of PD-1 Inhibitors in Immunotherapy for Glioblastoma. [PDF]
FASEB JThe molecular mechanism of PD‐1. When PD‐1 binds to PD‐L1, the ITIM and ITSM domains within PD‐1 are phosphorylated and subsequently recruit SHP‐2. This then dephosphorylates downstream molecules of the TCR, such as PI3K/AKT and ZAP70, reduces the secretion of IFN‐γ, and inhibits the presentation of antigens to T cells via MHC molecules through the ...
Dong MZ, Cui M, Qu LZ, Che HY, Guan HJ.
europepmc +2 more sources
Development of a Peptide Inhibitor Targeting the C-SH2 Domain of the SHP2 Phosphatase. [PDF]
ChembiochemA peptide inhibitor targeting the Src homology 2 (SH2) domain‐containing phosphatase 2 (SHP2) has been developed that binds to and blocks the C‐SH2 domain. The C‐SH2 inhibitor peptide is stable, selective, cell permeable, and noncytotoxic making it an enabling chemical tool to study SHP2 in cells.
Kiani A +11 more
europepmc +2 more sources
, 2022 EMBL-EBI IT department (Technical Services Cluster) governance structure including ITSM governance elements depicted in orange.
Montserrat Gonzalez-Ferreiro (12317246)
core +1 more source
Gamification in IT Service Management: A Systematic Mapping Study
Applied Sciences, 2021 Despite the benefits of adopting IT Service Management (ITSM) reference models, such initiatives do not always produce the expected results. The research literature in this area concludes that motivation, engagement, skills, experience, performance and ...
Manuel Trinidad +2 more
doaj +1 more source
Broadband inverted T-shaped seismic metamaterial
Materials & Design, 2021 Seismic metamaterials (SMs) are expected to assist or replace traditional isolation systems owing to their strong attenuation of seismic waves. In this work, a one-dimensional inverted T-shaped SM (1D ITSM) composed of arrays of inverted T-shaped ...
Yi Zeng +8 more
doaj +1 more source
New Supersonic Nozzle Test Rig Used to Generate Condensing Flow Test Data According to Barschdorff
International Journal of Turbomachinery, Propulsion and Power, 2023 Considerable progress has been achieved in recent decades in understanding the phenomena related to the onset of condensation in steam flows, both experimentally and especially numerically.
Manuel Ernesto Maqueo Martínez +3 more
doaj +1 more source
Digital Transformation of Public Sector Governance With IT Service Management–A Pilot Study
IEEE Access, 2023 Information Technology or IT is a combination of technology itself and a collection of IT services that ensure the effective implementation of overall Information Technology in an organization.
Muhammad Imran Sarwar +5 more
doaj +1 more source
Information, 2021 Information technology (IT) service management is considered a collection of frameworks that support organizations managing services. The implementation of these kinds of frameworks is constantly increasing in the IT service provider domain.
João Serrano +4 more
doaj +1 more source
Towards Accurate Predictions in ITSM: A Study on Transformer-Based Predictive Process Monitoring
Lecture Notes in Business Information ProcessingMarc C Hennig
exaly +2 more sources