Results 11 to 20 of about 1,762 (180)
The Application of PD-1 Inhibitors in Immunotherapy for Glioblastoma. [PDF]
The molecular mechanism of PD‐1. When PD‐1 binds to PD‐L1, the ITIM and ITSM domains within PD‐1 are phosphorylated and subsequently recruit SHP‐2. This then dephosphorylates downstream molecules of the TCR, such as PI3K/AKT and ZAP70, reduces the secretion of IFN‐γ, and inhibits the presentation of antigens to T cells via MHC molecules through the ...
Dong MZ, Cui M, Qu LZ, Che HY, Guan HJ.
europepmc +2 more sources
Digital Transformation of Public Sector Governance With IT Service Management–A Pilot Study
Information Technology or IT is a combination of technology itself and a collection of IT services that ensure the effective implementation of overall Information Technology in an organization.
Muhammad Imran Sarwar +5 more
doaj +1 more source
New Supersonic Nozzle Test Rig Used to Generate Condensing Flow Test Data According to Barschdorff
Considerable progress has been achieved in recent decades in understanding the phenomena related to the onset of condensation in steam flows, both experimentally and especially numerically.
Manuel Ernesto Maqueo Martínez +3 more
doaj +1 more source
Analysis of Information Technology Services Using the ITIL V.3 Framework
Information technology services have been widely used in various agencies. This is done because information technology services help many business processes in an agency. Government agencies, companies, and education are examples of agencies that utilize
Wildan Kristian Mahardika +1 more
doaj +1 more source
One alternative way to reduce the use of natural aggregate and asphalt is the use of recycled materials of old road pavement or Reclaimed Asphalt Pavement (RAP). The asphalt within the RAP generally had become stiffer due to ageing, therefore it needs to
I Nyoman Arya Thanaya, ME., PhD +2 more
doaj +1 more source
Solution space of interval linear programming model by new approach [PDF]
In this paper, solution space of interval linear programming (ILP) models that is a NP-hard problem, has been considered. In all of the solving methods of the ILP, feasibility condition has been only considered.
Mehdi Allahdadi, Hasan Mishmast Nehi
doaj +1 more source
Information technology (IT) service management is considered a collection of frameworks that support organizations managing services. The implementation of these kinds of frameworks is constantly increasing in the IT service provider domain.
João Serrano +4 more
doaj +1 more source
Information Technology (IT) is increasingly progressing. Nowadays, the success of a business of the organization/company is highly dependent on the IT infrastructure used.
Kornelius Irfandhi +5 more
doaj +1 more source
The Src homology-2 (SH2) domain-containing protein tyrosine phosphatase 2 (SHP2, encoded by PTPN11) is a critical allosteric phosphatase for many signaling pathways.
Quan Wang +3 more
doaj +1 more source
COLLABORATION MANAGEMENT FOR SUBJECTS OF EDUCATIONAL ACTIVITY IN INFORMATION-EDUCATIONAL SPACE
This article presents a conception of collaboration of main actors in information-educational space, based on service level management process from the library of best practices ITIL, composition and procedure of information interchange between actors ...
Yury F. Telnov +2 more
doaj +1 more source

