Results 51 to 60 of about 1,691 (179)

Analysis of Seismic Deformation from Global Three-Decade GNSS Displacements: Implications for a Three-Dimensional Earth GNSS Velocity Field

Remote Sensing, 2021
With the rapid development of Global Navigation Satellite System (GNSS) technology, the long-term accumulated GNSS observations of global reference stations have provided valuable data for geodesy and geodynamics studies since the 1990s.
Yingying Ren, Lizhen Lian, Jiexian Wang
doaj   +1 more source

Immune Surveillance and Immune Escape in Cancer: Mechanisms and Immunotherapy

MedComm, Volume 6, Issue 10, October 2025.
Our review focused on how specific cellular subsets crucial for igniting tumor immunity cycle, notably effector and helper T cells alongside antigen presentation cells, interact closely in both antigen‐dependent and ‐independent manners (within centered ring) adjacent to cancer cells.
Ying Peng, Linsheng Zhan, Jianxiang Shi, Jie Wang, Yueying Li, Xiangdong Sun, Jie Lv, Huiyu Yang, Zan Qiu, Xingzhao Liu, Chenyan Li, Shanshan Gong, Wen Jia, Huiying Wang, Yuqi Zhao, Bin Zhang, Wei Guo, Jiancheng Guo, Jian Shang, Qianqian Zhou, Yanan Yang, Feng Gao   +21 more
wiley   +1 more source

The Black Hole of Immune Checkpoint Blocking Therapy for Gastric Cancer: Hyperprogressive Disease

Cancer Science, Volume 116, Issue 10, Page 2630-2639, October 2025.
This review summarizes the mechanisms, predictive biomarkers, prevention, and treatment methods of HPD after immune checkpoint blockade therapy, providing a theoretical basis for making a judgment on the efficacy of ICI treatment for gastric cancer.
Zhuan‐Fang Wang, Chen‐Hui Ma, Ewetse Paul Maswikiti, Qin‐Ying Han, Li‐Juan He, Ben Liu, Zhi‐Jian Han, Hao Chen   +7 more
wiley   +1 more source

Cancer Immunotherapy in Combination with Radiotherapy and/or Chemotherapy: Mechanisms and Clinical Therapy

MedComm, Volume 6, Issue 9, September 2025.
Immunotherapy has revolutionized the clinical management of many malignancies. However, the presence of immune “cold” tumors limits objective response rates, highlighting the need for strategies to enhance the efficacy of immunotherapy. Radiotherapy has gained attention for its immunostimulatory abilities, particularly the “abscopal effect ...
Xinmin Wang, Jing Jing
wiley   +1 more source

The Melbourne Institute Data Lab, a Secure Access Environment for Informing Future Social and Economic Policy

Australian Economic Review, Volume 58, Issue 3, Page 259-271, September 2025.
ABSTRACT Policy analysts and academics play a critical role in informing policy design, implementation and evaluation. They apply their understanding of current social and economic issues, test theoretical frameworks and present new ideas that are a part of the ecosystem for promoting and sustaining efficient and equitable delivery of government ...
Chaminda Rajeev Samarage, A. Abigail Payne   +1 more
wiley   +1 more source

АНАЛИЗ ПРОБЛЕМНЫХ МОМЕНТОВ ПРИ ВНЕДРЕНИИ ПОДХОДА ITSM В ОРГАНИЗАЦИЯХ

Cifra: Информационные технологии и телекоммуникации
В статье обозначена проблема внедрения ITSM-подхода для совершенствования управления ИТ-сервисами организаций. Рассмотрена взаимосвязь этапов реализации данной методологии с точки зрения системного анализа.
Сазанова Л.А.
doaj   +1 more source

System of criteria for assessment of the practices for application of IT service management in Bulgaria [PDF]

Икономика и компютърни науки, 2020
The article studies specific question, concentrated in the border area between business management and IT, namely surveying aspects of relationships between the business organization (customer) and its IT department or external servicing IT company ...
Zahari Barbov
doaj  

T Cell Exhaustion and Function State Correlated With Outcomes in Patients With Intra‐Abdominal Candidiasis

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Introduction Intra‐abdominal candidiasis (IAC) still has a high mortality rate despite prompt antifungal therapy due to immunosuppression. T cell exhaustion is an important manifestation of immunosuppression. This study aimed to explore the expression pattern of exhaustion‐related molecules in patients with IAC and determine the possible ...
Yawen Xie, Jiahui Zhang, Guoyu Zhao, Xianli Lei, Hao Wang, Huaiwu He, Na Cui   +6 more
wiley   +1 more source

NKp30: A Key Membrane Molecule in the Fight Against Cancer and Infection

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
NKp30 is a crucial activating receptor on the surface of NK cells, mediating NK cell activation or the release of regulatory factors to exert cytotoxic effects by recognizing and binding to corresponding ligands. This article discusses the glycosylation of NKp30 and its pivotal role in antitumor and anti‐infection responses.
Yushu Shao, Yang Zhang, Jiaying Cao, Junyu He, Qian He, Yan Lei, Ning Tang, Yanhong Zhou   +7 more
wiley   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source