Results 81 to 90 of about 7,331 (198)

Concomitant Administration of Different Doses of Simvastatin with Ivabradine Influence on PAI-1 and Heart Rate in Normo- and Hypercholesterolaemic Rats

The Scientific World Journal, 2012
Ivabradine is a novel heart rate lowering agent that inhibits If ionic current in the sinus node and demonstrates antiischaemic and antianginal activity.
Jacek Owczarek, Magdalena Jasińska-Stroschein, Daria Orszulak-Michalak   +2 more
doaj   +1 more source

Cardioprotection by Ivabradine Through Heart Rate Reduction and Beyond

, 2011
The present review summarizes the experimental and clinical evidence for the anti-ischemic action of the selective bradycardic agent ivabradine. Improvements in myocardial blood flow and contractile function during experimental myocardial ischemia and ...
Gerd Heusch, Rainer Schulz, Andreas Skyschally   +2 more
core   +1 more source

Effects of ivabradine therapy on heart failure biomarkers

, 2015
WOS: 000364706900007PubMed: 25733317Background: Heart rate (HR) reduction is associated with improved outcomes in patients with heart failure (HF) and biomarkers can be a valuable diagnostic tool in HF management.
Ordu, Serkan, Ozsoy, A., Yildiz, B.S., Yıldız, Bekir Serhat, Kaftan, Havane Asuman, Alihanoğlu, Yusuf İzzettin, Tosun, Mehmet, Evrengül, Harun, Alihanoglu, Y.I., Özhan, Hakan, Ordu, S., Özsoy, Aybars   +11 more
core   +3 more sources

Ivabradine

Reactions Weekly, 2012
Scheinman, Melvin M., Vedantham, Vasanth
  +6 more sources

Acute Effects of Ivabradine on Dynamic Obstruction of the Left Ventricular Outflow Tract in Cats with Preclinical Hypertrophic Cardiomyopathy

Journal of Veterinary Internal Medicine, 2014
Background Ivabradine is a negative chronotropic drug with minimal effects on central hemodynamics. Its effect on dynamic obstruction of the left ventricular outflow tract (LVOT) in cats with hypertrophic cardiomyopathy (HCM) remains unknown.
K.A. Blass, K.E. Schober, X. Li, B.A. Scansen, J.D. Bonagura   +4 more
doaj   +1 more source

Selective HCN1 channels inhibition by ivabradine in mouse rod photoreceptors

, 2008
Purpose: To evaluate in mammalian rod photoreceptors the selectivity for hyperpolarization-activated cyclic nucleotide-gated (Hcn1, coded by Hcn1) over potassium-selective (Kir 2.4, coded by Kcnj14) channels of ivabradine, a selective inhibitor of the ...
CERVETTO, LUIGI, DEMONTIS, GIAN CARLO ALFREDO GIUSEPPE, PAOLI TG, GARGINI, MARIA CLAUDIA   +3 more
core   +1 more source

IVABRADINE VERSUS BISOPROLOL

, 2010
IVABRADINE VERSUS ...
NOVO, Giuseppina, VISCONTI, Claudia Luisa, DI GESARO, Gabriele, NOVO, Salvatore, D'ANGELO, Luciana, Passantino, S, Sarullo, F, FAZIO, Giovanni, Zarcone, P, Spanò, C, LICATA, Pamela   +10 more
core  

The ivabradine journey

, 2015
Large body of epidemiological evidence showed strong correlation between heart rate and total or cardiovascular (CV) mortality. These data do not, however, clarify the role of increased heart rate in CV disease, basically because they do not distinguish ...
FERRARI, Roberto
core   +1 more source

Ivabradine poisoning: a retrospective observational case series

Introduction Ivabradine is an anti-arrhythmic drug that targets the cardiac pacemaker funny current (If). It is used in the management of patients with uncontrolled angina, heart failure and postural orthostatic tachycardia syndrome.
Muhammad Nursuhairi Bin Sumarni, Katherine Zina Isoardi, Angela L. Chiew, Carol J. Wylie, Geoffrey K. Isbister   +4 more
core   +1 more source

The clinical and economic efficiency of treatment in patients with chronic heart failure

КардиоСоматика, 2013
Objective: to study the clinical and economic benefits of adding ivabradine to standard therapy for chronic heart failure (CHF). Subjects and methods.
E. I Tarlovskaya, S. V Malchikova
doaj