Results 61 to 70 of about 7,739 (166)

Inotropic Effects of Ivabradine in the Mammalian Heart

, 2010
Ivabradine represents a novel heart-rate-lowering agent that acts on the sino-atrial node supposedly by selectively inhibiting the ‘funny’ current (I_f current).
Klaus Pönicke, Joachim Neumann, Andreas Boldt, Rolf-Edgar Silber, Andreas Simm, Ulrich Gergs   +5 more
core   +1 more source

Effects of ivabradine therapy on heart failure biomarkers [PDF]

, 2015
WOS: 000364706900007PubMed: 25733317Background: Heart rate (HR) reduction is associated with improved outcomes in patients with heart failure (HF) and biomarkers can be a valuable diagnostic tool in HF management.
Ordu, Serkan, Ozsoy, A., Yildiz, B.S., Yıldız, Bekir Serhat, Kaftan, Havane Asuman, Alihanoğlu, Yusuf İzzettin, Tosun, Mehmet, Evrengül, Harun, Alihanoglu, Y.I., Özhan, Hakan, Ordu, S., Özsoy, Aybars   +11 more
core   +3 more sources

Ivabradine could not decrease mitral regurgitation triggered atrial fibrosis and fibrillation compared with carvedilol

ESC Heart Failure
Background Ivabradine, a medical treatment for heart failure (HF), reduces heart rate (HR) and prolongs diastolic perfusion time. It is frequently prescribed to patients with HF who have a suboptimal response or intolerance to beta‐blockers. Degenerative
Wei‐Chieh Lee, Yu‐Wen Lin, Jhih‐Yuan Shih, Zhih‐Cherng Chen, Nan‐Chun Wu, Wei‐Ting Chang   +5 more
doaj   +1 more source

Cost‐Effectiveness of Ivabradine for Heart Failure in the United States

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundIvabradine is a heart rate–lowering agent approved to reduce the risk of hospitalization for worsening heart failure. This study assessed the cost‐effectiveness of adding ivabradine to background therapy in the United States from the ...
Anuraag R. Kansal, Martin R. Cowie, Adrian Kielhorn, Stanimira Krotneva, Ali Tafazzoli, Ying Zheng, Nicole Yurgin   +6 more
doaj   +1 more source

Effectiveness of PAH Specific Treatment Is Comparable Between PAH Associated With Connective Tissue Disease and Idiopathic PAH: Data From the Multicentre National Registry

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a rare disease with poor prognosis. The same treatment is recommended in patients with PAH associated with connective tissue disease (CTD) and idiopathic PAH (IPAH). However, the effectiveness of PAH‐specific treatment in these both groups is inconsistent.
Anna Smukowska‐Gorynia, Sylwia Iwańczyk, Michał Ciurzyński, Marcin Waligóra, Marcin Kurzyna, Piotr Pruszczyk, Grzegorz Kopeć, Katarzyna Mizia‐Stec, Ilona Skoczylas, Łukasz Chrzanowski, Piotr Błaszczak, Katarzyna Ptaszyńska, Grzegorz Grześk, Ewa Malinowska, Małgorzata Peregud‐Pogorzelska, Michał Tomaszewski, Ewa Mroczek, Miłosz Jaguszewski, Ewa Lewicka, Katarzyna Widejko, Agnieszka Pawlak, Wojciech Jacheć, Zbigniew Gąsior, Katarzyna Betkier‐Lipińska, Judyta Winowska‐Józwa, Marta Banaszkiewicz, Tatiana Mularek‐Kubzdela   +26 more
wiley   +1 more source

EFFICACY AND SAFETY OF IVABRADINE AND BISOPROLOL IN PATIENTS WITH ISCHEMIC HEART DISEASE: RESULTS OF COMPARATIVE RANDOMIZED OPEN STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study influence of ivabradine as compared with bisoprolol on clinical and hemodynamic indices, exercise tolerance, endothelial function, quality of life (QL) and erectile function in patients with ischemic heart disease. Material and methods.
R. D. Kurbanov, A. O. Kan, F. M. Bekmetova, A. B. Shek   +3 more
doaj   +1 more source

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

The Journal of Physiology, Volume 604, Issue 13, Page 5159-5169, 1 July 2026.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

Ivabradine Use in Premature Infants With Accelerated Idioventricular Rhythm [PDF]

Introduction: Ivabradine has been recently introduced to treat focal atrial tachycardia and junctional ectopic tachycardia in children. Its use for treating ventricular tachyarrhythmias, specifically accelerated idioventricular rhythm (AIVR), remains ...
de Groot, Natasja M.S., Doctor, Pezad N., Ezekian, Jordan E., Tindel, Kaitlin, Nguyen, Hoang H., Ramdat Misier, Nawin L.   +5 more
core   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source