Results 51 to 60 of about 7,331 (198)

The effect of heart rate reduction by ivabradine on collateral function in patients with chronic stable coronary artery disease

open access: yes, 2014
Objective To evaluate the effect of heart rate reduction by ivabradine on coronary collateral function in patients with chronic stable coronary artery disease (CAD). Methods This was a prospective randomised placebo-controlled monocentre trial in a
Schild, Deborah   +7 more
core   +1 more source

Ivabradine Prevents Heart Rate Acceleration in Patients with Chronic Obstructive Pulmonary Disease and Coronary Heart Disease after Salbutamol Inhalation

open access: yesPharmaceuticals, 2012
Accelerated sinus rhythm is an important side effect of inhaled salbutamol which is especially harmful in patients with chronic obstructive pulmonary disease (COPD) and coronary heart disease (CHD). Cross-over, randomized, open label study design.
Uta C. Hoppe   +4 more
doaj   +1 more source

Doppler Echocardiography-Guided Heart Rate Modulation Therapy Using Ivabradine in a Patient with Systolic Heart Failure

open access: yesMedicina, 2022
Heart rate reduction using ivabradine, a selective If channel blocker that purely decreases heart rate without affecting hemodynamics, improves clinical outcomes in patients with systolic heart failure.
Teruhiko Imamura, Koichiro Kinugawa
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Volume 78, Issue 7, Page 860-874, July 2026.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

The isolated working guinea pig heart: A functional and electrophysiological characterisation

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3137-3151, 1 July 2026.
Abstract Small animal isolated perfused hearts have been used for over 150 years for the study of cardiac physiology and pharmacology. The guinea pig heart represents the smallest mammalian heart that replicates key features of the human heart – for example, with respect to cardiac action potential duration, ion channel expression, excitation ...
Grace C. Anderson‐Barker   +1 more
wiley   +1 more source

A possibility to interchange heart rate-slowing therapy with ivabradine and atenolol in patients with stable angina pectoris

open access: yesТерапевтический архив, 2013
AIM: To evaluate the efficiency and safety of an interchange of atenolol and ivabradine in patients who had stable angina pectoris without myocardial infarction in the history and left ventricular (LV) systolic dysfunction/MATERIAL AND METHODS: The trial
A A Shavarov   +2 more
doaj  

Management of Stable Angina with Ivabradine as Safe Alternative to Patients with Myasthenia Gravis

open access: yesCase Reports in Neurological Medicine, 2016
Management of cardiac symptoms in myasthenia gravis (MG) patients can be challenging. The aim of this report is to describe the safe use of ivabradine for stable angina in MG patients. A 48 y.o.
Giuliano Ohde Dalledone   +7 more
doaj   +1 more source

Anti-ischaemic effect of ivabradine

open access: yes, 2006
Ivabradine, the first representative of a new class of exclusive heart rate-reducing agents, selectively inhibits the I(f) current in the sinoatrial node.
CECONI, Claudio   +2 more
core   +1 more source

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

open access: yesThe Journal of Physiology, Volume 604, Issue 13, Page 5159-5169, 1 July 2026.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

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